Tag: treatment
What’s new in the extracorporeal treatment of sepsis?
Clinical research has shown that endotoxin is indeed circulating in the blood of up to 50% of sepsis shock patients and associated with impaired clinical outcome. In view of the pivotal role of endotoxin in sepsis patients,... read more
The ICM research agenda on ICU-acquired weakness
Intensive care unit (ICU)-acquired weakness (ICUAW) develops as a complication of critical illness and may represent the extreme end of a spectrum of weakness that begins with any serious illness regardless of care location.... read more
Decision Making Model Enables Resolution of Ethics Issues at the Bedside
A study from Switzerland that evaluated implementation of a stepped ethical decision-making model on three intensive care units (ICUs) and two geriatric wards found that it worked well, with staff able to find the time and... read more
Delirium in Critically Ill Children: An International Point Prevalence Study
In this multi-institutional, multinational point prevalence study of 994 subjects, delirium screening by the bedside nurse was feasible in children of all ages. PD was a common complication of critical illness, with a prevalence... read more
Never Stop Caring
I read with interest the piece by Wilson et al regarding their examination of end-of-life care patterns in hospitalized patients on their vascular surgery practice in Oregon. I applaud the authors for examining their practices... read more
Role of Combination Antimicrobial Therapy for Vancomycin‐Resistant Enterococcus faecium Infections
Enterococcus species are the second most common cause of nosocomial infections in the United States and are particularly concerning in critically ill patients with preexisting comorbid conditions. Rising resistance to antimicrobials... read more
Care that Matters: Quality Measurement and Health Care
Barry Saver and colleagues caution against the use of process and performance metrics as health care quality measures in the United States. There is limited evidence that many "quality" measures - including those... read more
Efficacy and safety of ticagrelor versus aspirin in acute stroke or transient ischaemic attack of atherosclerotic origin
Efficacy and safety of ticagrelor versus aspirin in acute stroke or transient ischaemic attack of atherosclerotic origin: a subgroup analysis of SOCRATES, a randomised, double-blind, controlled trial. In this prespecified... read more
Multifaceted educational intervention shortened time to antibiotic administration in children with sepsis
A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study. The Surviving Sepsis Campaign (SSC) recommends the administration... read more
Addressing Physician Burnout
The US health care delivery system and the field of medicine have experienced tremendous change over the last decade. At the system level, narrowing of insurance networks, employed physicians, and financial pressures have... read more
Cholesteryl Ester Crystals in Lysosomal Acid Lipase Deficiency
Deficiency of lysosomal acid lipase is a rare autosomal recessive lysosomal storage disease characterized by the accumulation of cholesteryl esters and triglycerides, predominantly in macrophages. Nonspecific clinical features... read more
Influenza and Considerations Regarding Infectious Mimics
The patient with headache, myalgia, and URI symptoms may just have the common flu. It's all too common to see and treat multiple patients with influenza-like illness during the flu season. But what could you be missing?... read more
Palliative care from diagnosis to death
Evidence is growing that people can benefit from palliative care earlier in their illness, say Scott Murray and colleagues, but care must be tailored to different conditions. Many people still associate palliative care with... read more
Electronic Dura Mater Meddling in the Central Nervous System
This review of preclinical applications assesses the potential of the electronic dura mater to deliver electrical and chemical stimulation to targeted areas of the central nervous system for extended periods. Soft neural... read more
GERD Treatment May Reduce Healthcare Visits for Acute Respiratory Infections
Treatment with proton pump inhibitors (PPIs) may help decrease healthcare visits for acute respiratory infections (ARIs) in patients with gastroesophageal reflux disease (GERD). These are the findings of a new study published... read more
Fecal microbiota transplantation a decolonization treatment option
The use of fecal microbiota transplantation is an option to eradicate highly drug-resistant enteric bacteria carriage, according to results from a small pilot study conducted by French investigators. A prospective study of... read more
POCT for emergency assessment of coagulation in patients treated with direct oral anticoagulants
Hemochron Signature Point-of-care testing (POCT) can be a fast and reliable alternative for guiding emergency treatment during rivaroxaban and dabigatran therapy. It allows the rapid identification of a relevant fraction... read more
Clinical practice guideline on diagnosis and treatment of hyponatraemia
Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms,... read more
CHS using virtual critical care for heart patients
It just might be the future of medicine. Using cameras, microphones and medical sensors, heart surgeons and cardiologists inside the Sanger Heart & Vascular Institute at Carolinas HealthCare System are treating patients... read more
How survival of cancer patients in critical care has improved in the last 3 decades
Comprehensive care for critically ill patients with cancer is a collaborative effort, and close cooperation between oncology as well as palliative and critical care is essential. Collaborative decision making is a cornerstone... read more
Thrombocytosis in the ED
Both reactive thrombocytosis and clonal thrombocytosis may be associated with vasomotor symptoms. The key difference is that thrombotic and bleeding events are much more common in myeloproliferative thrombocytosis, whereas... read more
