Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury

Therapeutic hypothermia is likely a beneficial treatment following traumatic brain injuries in adults but cannot be recommended in children.... read more

Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury

Seizures Prior to Diagnosis of Tuberous Sclerosis Complex

Seizures were a condition commonly experienced by patients prior to diagnosis of TSC; understanding the initial diagnoses experienced by TSC patients may help lead to earlier diagnosis and treatment of TSC. Many patients... read more

Seizures Prior to Diagnosis of Tuberous Sclerosis Complex

Disease Causation Index Established By New Mathematical Model

Patients with complex diseases have a higher risk of developing another. Multi-morbidity represents a huge problem in everyday clinical practice, because it makes it more difficult to provide successful treatment. By analysing... read more

Disease Causation Index Established By New Mathematical Model

Epstein-Barr risk increased by Immune Molecule Deficiency

Researchers from the National Institutes of Health National Institute of Allergy and Infectious Diseases, or NIAID, have found a genetic immune disorder causing increased risk and poor control of Epstein-Barr virus and EBV-associated... read more

Epstein-Barr risk increased by Immune Molecule Deficiency

Clinical challenge in IBD expanded by Systemic inflammation

More targeted antibody therapies carry the potential to transform how physicians treat inflammatory bowel disease. However, management can become less clear when IBD patients present with extra-intestinal manifestations.... read more

Clinical challenge in IBD expanded by Systemic inflammation

Think Sepsis and Act Fast

New attention to sepsis including revised definitions, updated guidelines, and new CMS reporting requirements aims to save lives through prevention and prompt and effective management of infections. CDC released a new Vital... read more

Think Sepsis and Act Fast

How nurses support families of ICU patients towards the end of life

Researchers gathered evidence on how nurses care for patients and their families in intensive care when life-sustaining treatment is withdrawn. The included studies explored the care of the family before, during and after... read more

How nurses support families of ICU patients towards the end of life

Mild electric e-scaffold disrupts bacterial biofilms

Researchers at Washington State University (Spokane, WA, USA) used an e-scaffold made out of conductive carbon fabric and a mild electrical current to produce a low, constant concentration of hydrogen peroxide (H2O2, an effective... read more

Mild electric e-scaffold disrupts bacterial biofilms

Non-antibiotic treatments for bacterial diseases in an antibiotic resistance era

The progressive spread of antibiotic resistance genes is forcing us to reconsider our treatment options against some bacterial pathogens. Treating bacterial infections will likely become more challenging in the future. We... read more

Non-antibiotic treatments for bacterial diseases in an antibiotic resistance era

Upright CT for lung cancer therapy planning used at Chicago Proton Center

The Northwestern Medicine Chicago Proton Center will be the first proton center in the U.S. to use P-Cure new P-ARTIS CT on patients being treated for lung cancer. Traditionally, patients lie flat on their backs during CT... read more

Upright CT for lung cancer therapy planning used at Chicago Proton Center

Reducing Natalizumab Concentration May Reduce PML Risk

Serum concentrations of natalizumab do not appear to rise before patients with relapsing-remitting multiple sclerosis are diagnosed with progressive multifocal leukoencephalopathy, contradicting the hypothesis that exposure... read more

Reducing Natalizumab Concentration May Reduce PML Risk

Cooling patients with TBI improve survival chances

New research from Royal Holloway published today in Critical Care Medicine shows that lowering the body temperature of people who have suffered a traumatic brain injury (TBI) as soon as possible after the trauma may significantly... read more

Cooling patients with TBI improve survival chances

Plazomicin Succeeds in Phase 3 cUTI and CRE Trial

Plazomicin an antibiotic being developed to fight multidrug-resistant bacterial infections, has met the primary objective of noninferiority compared with meropenem in a phase 3 registration trial among patients with complicated... read more

Plazomicin Succeeds in Phase 3 cUTI and CRE Trial

Glutamine, fish oil and antioxidants in critical illness

We hypothesize that the harmful effect of IMHP compared to HP enteral nutrition in a heterogeneous group of critically ill patients is limited to the medical critically ill patients and mediated by an early increase in (epa... read more

Glutamine, fish oil and antioxidants in critical illness

Non-invasive Respiratory Support and Methylxanthines Reduce Re-Intubations

In a meta-analysis of randomized studies evaluating efforts to reduce re-intubations and respiratory failure in preterm infants, non-invasive respiratory support and use of methylxanthines (theophylline, caffeine) were found... read more

Non-invasive Respiratory Support and Methylxanthines Reduce Re-Intubations

The role of POC Diagnostics in Combatting Antibiotic Resistance

During the winter months, patients frequently present with respiratory symptoms like coughing, sneezing and fever that could be caused by one of several bacterial and viral infections including influenza, respiratory syncytial... read more

The role of POC Diagnostics in Combatting Antibiotic Resistance

Randomised trials role in surgery

In medical science, as in all walks of life, we are impressed by dramatic effects.  If a new treatment seems much better than an old one initially, there is often impatience to get on and use it, and people question why... read more

Randomised trials role in surgery

RSNA attendees warned by FBI about the threat of radiation theft from hospitals

FBI and Department of Energy reps briefed a room full of RSNA attendees in Chicago last week about a growing litany of concerns ranging from disgruntled medical employees stealing radioactive materials, to patients setting... read more

RSNA attendees warned by FBI about the threat of radiation theft from hospitals

Antibiotic therapy advances in the critically ill

Key issues related to antibiotic management in the critically ill, including problems associated with timing, duration, and dosing of antibiotics. The authors highlighted the importance of early diagnosis of infection and... read more

Antibiotic therapy advances in the critically ill

Testosterone VTE Risk; Novel Clot Buster Flops Again; Saturated Fat Culpability

The venous thromboembolism (VTE) risk warned about with testosterone treatment appears to be transient, peaking within 6 months after starting and then gradually declining.... read more

Testosterone VTE Risk; Novel Clot Buster Flops Again; Saturated Fat Culpability

Pulmaquin Looks Promising for Treating Lung Infections in Non-CF Bronchiectasis Patients

Aradigm has announced top-line results from two Phase 3 clinical trials of Pulmaquin (inhaled ciprofloxacin) for the treatment of patients with non-cystic fibrosis bronchiectasis (non-CF BE) who have chronic lung infections... read more

Pulmaquin Looks Promising for Treating Lung Infections in Non-CF Bronchiectasis Patients