Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients

This Bayesian network meta-analysis demonstrated the comparative effectiveness of fifteen antimicrobial treatments for drug-resistant A. baumannii pneumonia in critically ill patients. For survival benefit, SUL appears to... read more

Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients

Trends and Patterns of Antibiotic Consumption in China

The consumption of antibiotics is a major driver in the development of antimicrobial resistance. This study aims to identify the trends and patterns of the total antibiotic consumption in China’s tertiary hospitals from... read more

Trends and Patterns of Antibiotic Consumption in China

Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium

Among patients with acute respiratory distress syndrome (ARDS), cisatracurium does not improve mortality versus vecuronium but is associated with improvements in other outcomes, according to a study published online in the... read more

Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium

Elevated BNP Levels in CFS Associated with Cardiac Dysfunction

This study confirms an association between reduced cardiac volumes and brain natriuretic peptide (BNP) in chronic fatigue syndrome (CFS). Lack of relationship between length of disease suggests that findings are not secondary... read more

Elevated BNP Levels in CFS Associated with Cardiac Dysfunction

Clinicians’ Expectations of the Benefits and Harms of Treatments, Screening, and Tests

Clinicians rarely had accurate expectations of benefits or harms, with inaccuracies in both directions. However, clinicians more often underestimated rather than overestimated harms and overestimated rather than underestimated... read more

Clinicians’ Expectations of the Benefits and Harms of Treatments, Screening, and Tests

Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants

In this randomized clinical trial that included 470 patients who were undergoing surgery for removal of orthopedic implants used for treatment of below-the-knee fractures, surgical site infection occurred in 12.9% of patients... read more

Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants

The Iatrogenic Potential of the Physician’s Words

Some of the information that physicians convey to their patients can inadvertently amplify patients' symptoms and become a source of heightened somatic distress, an effect that must be understood by physicians to ensure optimal... read more

The Iatrogenic Potential of the Physician’s Words

A Research Agenda for Communication Between Health Care Professionals and Patients Living With Serious Illness

Poor communication by health care professionals contributes to physical and psychological suffering in patients living with serious illness. Patients may not fully understand their illness, prognosis, and treatment options... read more

A Research Agenda for Communication Between Health Care Professionals and Patients Living With Serious Illness

Endoscopic Treatment versus Shunting for Hydrocephalus

In sub-Saharan Africa, a large number of infants are affected by hydrocephalus that develops after neonatal ventriculitis and is often associated with poor developmental outcomes. New research findings are summarized in a... read more

Endoscopic Treatment versus Shunting for Hydrocephalus

Dietitians in Critical Care

Patients in the critical care setting are at risk of malnutrition. The provision of nutrition support (enteral or parenteral) to critically ill patients is vital, but achieving the optimum quantity and balance is a contentious... read more

Dietitians in Critical Care

Inpatient antiviral treatment reduces ICU admissions among influenza patients

Administering inpatient antiviral influenza treatment may reduce admissions to the ICU among adults hospitalized with flu, according to a study presented at ID Week 2017, an infectious diseases meeting. While interventions... read more

Inpatient antiviral treatment reduces ICU admissions among influenza patients

Is Simvastatin the Miracle Drug We Think It Is?

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation. This well designed and conducted trial demonstrates that there is... read more

Is Simvastatin the Miracle Drug We Think It Is?

Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

The post-thrombotic syndrome frequently develops in patients with proximal deep-vein thrombosis despite treatment with anticoagulant therapy. Pharmacomechanical catheter-directed thrombolysis (hereafter "pharmacomechanical... read more

Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

Music and Medicine: Something Important

Every week or 2 when I don’t have a daytime shift, I set up my iPad and play piano for an hour or so. Nothing depressing or too complicated—feel-good music from the 1930s to the latest by John Legend or Coldplay. The... read more

Music and Medicine: Something Important

Effects of Physical Activity on Poststroke Cognitive Function

Despite the social, health, and economic burdens associated with cognitive impairment poststroke, there is considerable uncertainty about the types of interventions that might preserve or restore cognitive abilities. The... read more

Effects of Physical Activity on Poststroke Cognitive Function

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.... read more

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction... read more

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus