Humanizing the Treatment of Hyperactive Delirium in the Last Days of Life

Humanizing the Treatment of Hyperactive Delirium in the Last Days of Life

When patients with advanced cancer near the end of their life, it is important for physicians, nurses, and other health care personnel to respect and dignify the dying process of the patient. This requires a shift in focus... read more

Oestrogen Inhibition Reverses PAH and Associated Metabolic Defects

Oestrogen Inhibition Reverses PAH and Associated Metabolic Defects

Increased oestrogen is a strong epidemiological risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic defects. In addition, oestrogens drive penetrance in mice carrying... read more

Addressing Antimicrobial Resistance and Stewardship

Addressing Antimicrobial Resistance and Stewardship

Antimicrobial-resistant infections affect more than 2 million people annually in the United States alone, accounting for an estimated 23 000 deaths and estimated economic costs of $55 billion. Recent projections suggest... read more

Systematic review suggests synovial fluid analysis when necessary for diagnosis of gout

Systematic review suggests synovial fluid analysis when necessary for diagnosis of gout

Gout presents with acute attacks of synovitis that start out as intermittent but can advance to chronic symptoms.... read more

Efficacy of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation

Efficacy of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation

This study demonstrates that Shenfu injection in combination with conventional postresuscitation care bundle treatment is effective at improving clinical outcomes in patients with return of spontaneous circulation after in-hospital... read more

Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery

Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery

Sodium nitroprusside (SNP) has been used clinically for decades for the treatment of hypertension associated with cardiac surgery.... read more

Hypertension and Prehypertension Underdiagnosed, Undertreated in U.S. Children

Hypertension and Prehypertension Underdiagnosed, Undertreated in U.S. Children

Hypertension and prehypertension in children often go undiagnosed, according to a new study published in Pediatrics. The study focused on children with abnormal blood pressures across the United States.... read more

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Ingredient in aspirin combined with popular diabetes drug can turn off faulty protein that plays a key role in inflammatory diseases, such as rheumatoid arthritis. ... read more

Sepsis National Hospital Inpatient Quality Measure

Sepsis National Hospital Inpatient Quality Measure

The Center for Medicare and Medicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance measure to the Hospital Inpatient Quality Reporting Program in July 2015 to help address the... read more

Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI

Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI

Substantial variation was found regarding monitoring and treatment policies in patients with Traumatic Brain Injury (TBI) and intracranial hypertension. The results of this survey indicate a lack of consensus between European... read more

The Overlaps of Asthma or COPD with OSA

The Overlaps of Asthma or COPD with OSA

Asthma, chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are the most common respiratory disorders worldwide. Given demographic and environmental changes, prevalence for each is likely to increase. Some... read more

Examining When to Provide Pain Management for Patients

Examining When to Provide Pain Management for Patients

Sometimes a lack of pain medication is the patient's best form of treatment. Eradicating pain has been a focus of medicine throughout history, from the early use of cocaine to the current use of fentanyl. As a prehospital... read more

CDC Urges Early Recognition, Prompt Treatment of Sepsis

CDC Urges Early Recognition, Prompt Treatment of Sepsis

The Centers for Disease Control and Prevention today launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis. This initiative emphasizes the importance of early... read more

A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation

A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation

Oral anticoagulation is underused in patients with atrial fibrillation. We assessed the impact of a multifaceted educational intervention, versus usual care, on oral anticoagulant use in patients with atrial fibrillation.... read more

FDA Approves ‘living drug’ to Cure Cancer

FDA Approves ‘living drug’ to Cure Cancer

FDA has approved the first treatment to redesign immune system so it attacks the cancer cells. Kymriah therapy, which leaves 83% of people free of a type of blood cancer, costs about $475,000 and was developed by Novartis.... read more

Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation

Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation

Individualized autoregulation-guided cerebral perfusion pressure management may be a plausible alternative to fixed cerebral perfusion pressure threshold management in severe traumatic brain injury patients. Prospective randomized... read more

Antibiotic Guidelines Improve Prescription Practices for Vulnerable Infants

Antibiotic Guidelines Improve Prescription Practices for Vulnerable Infants

Yale University School of Medicine neonatal intensive care unit (NICU) significantly reduced the number of cases of late-onset sepsis, a leading cause of death among pre-term infants, by implementing guidelines designed to... read more