Improving Patient Outcomes: Sepsis Protocols and Rapid Host Response Technologies

Patients come into the emergency department (ED) with symptoms, not diagnoses. That’s when time is of the essence. Clinicians must quickly triage patients and establish an appropriate care pathway to obtain the best possible... read more

Predictive Biomarkers of Mortality in ICU Patients with Severe COVID-19

This study shows changes in hematological, biochemical, and inflammatory parameters in COVID-19 non-surviving patients. Lymphopenia, neutrophilia, and thrombocytopenia, as well as increased levels of CRP, AST, creatinine,... read more

Troponin Role in the Diagnosis and Treatment of Acute Pulmonary Embolism

Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences, wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article reviews the various roles of Tn in managing... read more

Glucose Metabolism Disorders: Pre-hospital Oxygen Therapy and Saturation Variability in COVID-19 Patients

The COVID-19 pandemic has revealed that viruses can have multiple receptor properties, penetrating various tissues and causing mutations in various genes, thus promoting a range of metabolic disorders. The purpose of... read more

A Promising Biomarker for Early Detection of Acute Coronary Syndrome (ACS)

A Promising Biomarker for Early Detection of Acute Coronary Syndrome (ACS)

As found in our study, among the biomarkers used, the diagnostic accuracy of IMA was the highest and better than that of cardiac troponin I and CK-MB. Although ECG is the preferred diagnostic tool for diagnosing ACS (STEMI,... read more

High-Sensitivity Troponin T in a Secondary Care Setting

High-Sensitivity Troponin T in a Secondary Care Setting

High-sensitivity troponin (hs-cTn) assays play a crucial role in the early detection and management of patients with suspected acute coronary syndrome (ACS). This study supports evidence that serial troponin measurements... read more

Effective Treatment for Combined Amlodipine and Metformin Overdose

Effective Treatment for Combined Amlodipine and Metformin Overdose

The combined toxicity of amlodipine and metformin is a rarely reported phenomenon in the literature. The management varies depending on the clinical status of the patient. We present a case that was managed successfully... read more

High-risk Pulmonary Embolism in the ICU

High-risk Pulmonary Embolism in the ICU

According to the European guidelines, high-risk pulmonary embolism (PE) is defined as PE associated with hemodynamic instability, including sustained hypotension, cardiogenic shock and/or cardiac arrest. High-risk PE... read more

MACE in Acute Exacerbation of COPD – Troponin I – A Dramatic Predictor

MACE in Acute Exacerbation of COPD – Troponin I – A Dramatic Predictor

The burden of COPD is rising due to continued exposure to risk factors that trigger lung inflammation and repeated secondary infections thereby contributing to the third leading cause of death globally. More COPD deaths... read more

Troponins for SVT Set the Stage for Patient Harm

Troponins for SVT Set the Stage for Patient Harm

Many laboratory tests are routinely ordered for reassurance. We almost always order a hemoglobin and pregnancy test when a patient has syncope, despite knowing the vast majority will be normal. These tests are accurate... read more

Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic

Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic

The coronavirus disease (COVID-19) pandemic has challenged healthcare systems and has resulted in complex diagnostic processes for patients with non-COVID-19 pathology. Here, we demonstrate a case of massive alveolar... read more

Troponin Elevation in Non-cardiac Critical Illness

Troponin Elevation in Non-cardiac Critical Illness

This article is about how to approach ischemia evaluation for the "non-cardiac" critically ill patient (someone admitted for a problem such as sepsis, stroke, or DKA). This is tough. We want to be thorough enough not to miss... read more

Single Troponin Testing in ED Patients With Suspected Acute Myocardial Infarction

Single Troponin Testing in ED Patients With Suspected Acute Myocardial Infarction

One of the most common reasons for Emergency Department (ED) visits is chest pain. While most of these presentations are at a low risk for cardiac events, it is generally required to perform a full work-up to rule out an... read more

Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children

Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children

Acute myocarditis with intense systemic inflammation and atypical Kawasaki disease is an emerging severe pediatric disease following SARS-CoV-2 infection. Early recognition of this disease is needed and referral to an expert... read more

Research Shows Increased Thrombus Burden in COVID-19 Patients With STEMI

Research Shows Increased Thrombus Burden in COVID-19 Patients With STEMI

There may be a strong signal towards higher thrombus burden and poorer outcomes in COVID-19 patients presenting with STEMI, supporting the need for establishing COVID-19 status in all STEMI cases, according to a study published... read more

First Case of COVID-19 Complicated With Fulminant Myocarditis

First Case of COVID-19 Complicated With Fulminant Myocarditis

COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. This is the first report of COVID-19 complicated with fulminant myocarditis. The mechanism of cardiac pathology caused by COVID-19... read more

Circulating Secretoneurin Concentrations After Cardiac Surgery

Circulating Secretoneurin Concentrations After Cardiac Surgery

Circulating postoperative secretoneurin concentrations provide incremental prognostic information to established risk indices in patients undergoing cardiac surgery. Preoperative and postoperative secretoneurin concentration... read more