COVID-19 in the Air: The Hidden Viral Footprint in Hospital Waiting Rooms

New research from the Kirby Institute reveals that COVID-19 genetic material is frequently present in hospital air during community outbreaks, even in facilities with high-quality ventilation. By sampling air and surfaces... read more

Balancing the Breath: Navigating the Brain-Lung Connection in Acute Brain Injury

This study explores the delicate tug-of-war between mechanical ventilation (MV) and outcomes for patients with Acute Brain Injury (ABI). The researchers highlight that the way we breathe for a patient can significantly influence... read more

Lost in Translation: Unmasking the Silent Struggle of Ineffective Ventilator Efforts

While identifying the subtle timing mismatches between a patient and a ventilator often requires specialized internal monitoring, clinicians can still spot major "asynchronies" by closely watching the flow and pressure curves... read more

Obesity Paradox or Myth? BMI Shows No Impact on Sepsis Survival in ICU Patients

This retrospective cohort study examined the association between body mass index (BMI) and clinical outcomes in 559 adult ICU patients with sepsis admitted between January 2021 and December 2023. Patients were categorized... read more

Reducing Mortality in Critically Ill Patients

This book describes the techniques, strategies, and drugs that have been demonstrated by multicenter randomized trials to influence survival in critically ill patients, defined as those who have acute failure of at least... read more

Reducing Mortality in Critically Ill Patients

Move Early, Recover Faster: Early Mobilization Slashes ICU Stays Without Adding Risk

An updated systematic review and meta-analysis of 16 high-quality randomized trials (2,385 ICU patients) delivers a clear verdict: starting mobilization within 72 hours of admission is not only safe but powerfully effective.... read more

Ventilator Management: A Pre-Hospital Perspective

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... read more

Ventilator Management: A Pre-Hospital Perspective

Optimizing Sedation & Analgesia in the ICU, An Issue of Critical Care Clinics, E-Book (The Clinics: Internal Medicine)

In this issue of Critical Care Clinics, guest editors Drs. Yahya Shehabi, Joanna L. Stollings, and Timothy D. Gerard bring their considerable expertise to the topic of Optimizing Sedation and Analgesia in the ICU. Top... read more

Optimizing Sedation & Analgesia in the ICU, An Issue of Critical Care Clinics, E-Book (The Clinics: Internal Medicine)

Critical Care & ICU Made Simple: The Illustrated Bedside Manual for Fast Decision-Making and Real-World Patient Management

Are you overwhelmed by complex ICU textbooks that make critical care harder, not easier? Do you wish you had a practical critical care handbook that helps you make the right call in seconds, not hours? You’ve just found... read more

Critical Care & ICU Made Simple: The Illustrated Bedside Manual for Fast Decision-Making and Real-World Patient Management

Restoring Voices: Safety and Success of In-Line Speaking Valves

A retrospective cohort study evaluated the safety and tolerability of placing a speaking valve directly in-line with the ventilator circuit for critically ill, tracheostomized patients who were difficult to wean from mechanical... read more

PEEP’s Hidden Impact: The Rise in Mechanical Power

This study investigated how a stepwise increase in Positive End-Expiratory Pressure (PEEP) affects respiratory mechanics and mechanical power in mechanically ventilated adults. Using an incremental titration strategy,... read more

Mastering Non-Invasive Respiratory Support: A Guide to Success

This clinical guide provides an overview of non-invasive respiratory support (NIRS) techniques—including High-Flow Nasal Therapy (HFNT), Continuous Positive Airway Pressure (CPAP), and Bilevel Positive Airway Pressure (BiPAP)-for... read more

Gut Feeling vs. Data: SDD Doesn’t Beat Standard Care for Ventilated Patients

This multi-center trial, spanning 26 Intensive Care Units (ICUs) in Australia and Canada and involving over 20,000 critically ill patients on mechanical ventilation, put a long-debated practice, Selective Decontamination... read more

The Crystal Ball of the ICU: Machine Learning Predicts Who’s Staying and Who’s Not

The PREMIER Study dove into the data of 996 patients experiencing Acute Hypoxemic Respiratory Failure (AHRF) who had been on mechanical ventilation (MV) for at least two days, aiming to develop a reliable way to predict their... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

In the present book, a broad description of the processes carried out in patients with mechanical ventilation in the ICU is made. It covers from an overview of mechanical ventilation and some of its history to the processes... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

Bedside Procedures in the ICU

This handbook is a guide to best practice in interventions commonly encountered in the ICU. It is clinically orientated providing step-by-step explanations and illustrations of most invasive procedures, check lists to make... read more

Bedside Procedures in the ICU

The Hidden Danger of Insufficient Sedation in ARDS

This prospective observational study highlights a critical issue in the Intensive Care Unit (ICU): a substantial number of patients with Acute Respiratory Distress Syndrome (ARDS) receiving continuous neuromuscular blockade... read more

Hemodynamics: The Key to Noninvasive Ventilation (NIV) Success

This large multicenter observational study found that hemodynamic instability—defined as needing vasopressor support within 24 hours of starting NIV—was linked to a significantly higher risk of NIV failure. The crucial... read more

VIS to Win: Predicting Mortality After Infective Endocarditis Surgery

This study explored the predictive power of the Vasoactive-Inotropic Score (VIS) in patients who underwent valve replacement surgery for infective endocarditis (IE). The key finding is that the VIS is a strong and superior... read more

Basics of Mechanical Ventilation

This book is a practical and easily understandable guide for mechanical ventilation. With a focus on the basics, this text begins with a detailed account of the mechanisms of spontaneous breathing as a reference point to... read more

Basics of Mechanical Ventilation

Predicting Mortality in Sepsis-Related ARDS Using Machine Learning

The application of machine learning methodologies to construct prognostic prediction models for sepsis patients complicated by ARDS, informed by the new global definition, proves to be reliable. This approach can assist clinicians... read more

Managing Opioid Requirements for Buprenorphine/Naloxone Patients on Ventilators

In a study of 176 mechanically ventilated patients, researchers found that patients who were taking buprenorphine/naloxone before they were admitted to the hospital had similar opioid requirements during ventilation as those... read more