Tag: ventilation
Non-invasive Respiratory Support and P-SILI in COVID-19
Coronavirus disease 2019 (COVID-19) pneumonia is associated with hypoxemic respiratory failure, ranging from mild to severe. Due to the worldwide shortage of intensive care unit beds, a relatively high number of patients... read more
Protocol and statistical analysis plan for the PREPARE II randomised clinical trial
Cardiovascular collapse is a common complication during tracheal intubation of critically ill adults. Whether administration of an intravenous fluid bolus prevents cardiovascular collapse during tracheal intubation remains... read more
Why and How to Open ICU to Family Visits During the Pandemic
Since the lockdown because of the pandemic, family members have been prohibited from visiting their loved ones in hospital. While it is clearly complicated to implement protocols for the admission of family members, we believe... read more
Steer Clear of Magnesium for COPD
Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more
NIV After Early Extubation Reduces Total Days Spent on i-MV
Patients recovering from an episode of hypoxemic acute respiratory failure (hARF) may benefit from a weaning strategy based on early extubation followed by immediate noninvasive ventilation (NIV) application. Compared... read more
Risk of Clinical Severity by Age and Race/Ethnicity Among Adults Hospitalized for COVID-19
Older adults and people from certain racial and ethnic groups are disproportionately represented in coronavirus disease 2019 (COVID-19) hospitalizations and deaths. Using data from the Premier Healthcare Database on 181,813... read more
Clinical strategies for implementing lung and diaphragm-protective ventilation
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm develops atrophy as a consequence of low... read more
Sedation, Analgesia, and Paralysis in COVID-19 Patients in the Setting of Drug Shortages
The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a global pandemic. The 2019 coronavirus disease (COVID-19) presents with a spectrum of symptoms ranging from mild to critical... read more
COVID-19: Dual Oxygen Concentrator System for Mechanical Ventilation
Sabah in Malaysian Borneo is among the Malaysian states which reported a high number of detected COVID-19 cases during the current pandemic. Due to geographical challenges and limited resources, clinicians developed novel... read more
Promoting Evidence-Based Practice in ARDS
There is a dearth of literature addressing interventions to improve implementation of evidence-based practices in acute respiratory distress syndrome (ARDS). Existing interventions to improve clinician knowledge and facilitate... read more
Remestemcel-L reduces ARDS mortality in those under 65 years old
New data shows patients with COVID-19-related Acute Respiratory Distress Syndrome (ARDS) were up to 75 percent less likely to die when treated with remestemcel-L and dexamethasone. The data shows remestemcel-L reduced... read more
Prone Positioning in Spontaneously Breathing Subjects With Moderate or Severe ARDS During Invasive Ventilation
In a retrospective analysis of consecutive intubated subjects with moderate or severe ARDS, related or not to COVID-19, spontaneous breathing during prone positioning (PP) was well tolerated and achieved significant improvement... read more
Critical Care Emergency Medicine
The groundbreaking text on critical care emergency medicine – updated with the latest evidence and recommendations. Critical Care Emergency Medicine has become the standard reference for all clinicians who wish to understand... read more
Prone Positioning of Nonintubated Patients with COVID-19
Despite the significant variability in frequency and duration of prone positioning and respiratory supports applied, prone positioning was associated with improvement in oxygenation variables without any reported serious... read more
Expiratory Flow Limitation During Mechanical Ventilation
Expiratory flow limitation (EFL) is present when the flow cannot rise despite an increase in the expiratory driving pressure. The mechanisms of EFL are debated but are believed to be related to the collapsibility of small... read more
Assess the Intensity of Inspiratory Efforts Using CVP Waveforms
Real case: You are passing by the room of an awake mechanically ventilated patient with advanced IPF. Peeking in from outside the room, the following CVP waveform catches your attention. In a recent post, we discussed... read more
Comparison of the Efficacy and Safety of Cuffed vs. Uncuffed Endotracheal Tubes for Infants in the Intensive Care
There was no difference in the primary outcome, though percentage time spent in optimal leak range was significantly higher in cuffed uncuffed endotracheal tube (ETT) group. Cuffed ETTs reduced reintubations to optimise ETT... read more
90 Day Outcomes of COVID-19 Patients in European ICUs
This communication delineates outcomes in COVID-19 patients in the context of ARDS severity, ventilatory management, and variables associated with mortality on a 90-day follow-up for subgroups of patients after ICU admission.... read more
Co-infection in Critically Ill Patients with COVID-19
During previous viral pandemics, reported co-infection rates and implicated pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness and death was complicated by bacterial co-infection,... read more
Individualized vs. Fixed Positive End-expiratory Pressure for Intraoperative Mechanical Ventilation in Obese Patients
This secondary analysis of obese patients undergoing laparoscopic surgery found better oxygenation, lower driving pressures, and redistribution of ventilation toward dependent lung areas measured by electrical impedance tomography... read more
COVID-19: Critical Care and Airway Management Issues
Among patients hospitalized with coronavirus disease 2019 (COVID-19), up to one-quarter require intensive care unit (ICU) admission. Profound hypoxemic respiratory failure from acute respiratory distress syndrome (ARDS)... read more
Operative Lung Deflation During OLV with a DL-ETT
Operative lung deflation during lung deflation during one-lung ventilation (OLV) with a double-lumen endotracheal tube (DL-ETT) is faster when the operative lumen remains closed before pleural opening thus preventing it from... read more
