Physiological dead space and alveolar ventilation in ventilated infants

Physiological dead space and alveolar ventilation in ventilated infants

Prematurely born infants with pulmonary disease have a higher dead space than term controls, which may influence the optimum level during volume-targeted ventilation. A prospective study of mechanically ventilated infants... read more

Innovations in ICU Ventilation

Innovations in ICU Ventilation

Many centuries ago, Socrates stated that "the secret of change is to focus all of your energy, not on fighting the old, but on building the new." Nowadays, we may relate his quote with the concept of innovation, which is... read more

Haloperidol, Clonidine and Resolution of Delirium in Critically Ill Patients

Haloperidol, Clonidine and Resolution of Delirium in Critically Ill Patients

Haloperidol and clonidine use in delirious ICU patients may be associated with reduced probability of delirium resolution. This finding, however, merits further investigation given inherent limitations of this observational... read more

COVID-19 and VILI: Mechanical Power Measurement

COVID-19 and VILI: Mechanical Power Measurement

The COVID-19 pandemic has increased the need for a bedside tool for lung mechanics assessment and ventilator-induced lung injury (VILI) monitoring. Mechanical power is a unifying concept including all the components which... read more

Nebulised heparin for patients with or at risk of ARDS

Nebulised heparin for patients with or at risk of ARDS

In patients with or at risk of acute respiratory distress syndrome (ARDS), nebulised heparin did not improve self-reported performance of daily physical activities, but was well tolerated and exploratory outcomes suggest... read more

Association between the BMI and outcomes of patients resuscitated from OHCA

Association between the BMI and outcomes of patients resuscitated from OHCA

The body mass index (BMI) was not independently associated with favourable neurologic and survival outcomes of patients surviving from out-of-hospital cardiac arrest (OHCA). Nine hospitals were enrolled; finally, 605 patients... read more

Basics of Mechanical Ventilation

Basics of Mechanical Ventilation

This book is a practical and easily understandable guide for mechanical ventilation. With a focus on the basics, this text begins with a detailed account of the mechanisms of spontaneous breathing as a reference point to... read more

Bacterial Superinfection Pneumonia in COVID-19 Respiratory Failure

Bacterial Superinfection Pneumonia in COVID-19 Respiratory Failure

Severe community-acquired pneumonia secondary to SARS-CoV-2 is a leading cause of death. Current guidelines recommend patients with SARS-CoV-2 pneumonia receive empirical antibiotic therapy for suspected bacterial superinfection,... read more

Pre-hospital critical care management of severe hypoxemia in victims of COVID-19

Pre-hospital critical care management of severe hypoxemia in victims of COVID-19

Patients with Covid-19 and severe hypoxemia may pose a considerable challenge for the pre-hospital emergency medical services. Intubation may be associated with a high risk of complications in these patients and should be... read more

Adverse Events in the ICU During Bed-Bath Procedures

Adverse Events in the ICU During Bed-Bath Procedures

Serious adverse events were observed in one-half of patients and concerned one-fifth of nurses, confirming the need for caution. Further studies are needed to test systematic serious adverse event prevention strategies. The... read more

A Novel Negative Pressure-Flow Waveform to Ventilate Lungs for Normothermic Ex Vivo Lung Perfusion

A Novel Negative Pressure-Flow Waveform to Ventilate Lungs for Normothermic Ex Vivo Lung Perfusion

Ex vivo lung perfusion (EVLP) is increasingly used to treat and assess lungs before transplant. Minimizing ventilator induced lung injury (VILI) during EVLP is an important clinical need, and negative pressure ventilation... read more

Medical officials use new tool for COVID patients

Medical officials use new tool for COVID patients

The Barren-Metcalfe County Emergency Medical Service will soon implement a new medical device that will benefit COVID-19 patients as well as emergency medical personnel. The medical device, the Sea-Long helmet, is a clear,... read more

Extracorporeal Membrane Oxygenation for COVID-19

Extracorporeal Membrane Oxygenation for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed... read more

Time-Controlled Adaptive Ventilation Versus Volume-Controlled Ventilation in Experimental Pneumonia

Time-Controlled Adaptive Ventilation Versus Volume-Controlled Ventilation in Experimental Pneumonia

In the model of pneumonia used herein, at the same tidal volume and mean airway pressure, time-controlled adaptive ventilation, compared with volume-controlled ventilation, was associated with less lung damage and bacteremia... read more