Equipotent Ratios for the Most Common Vasopressors

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Calculating equipotent doses between vasopressor agents is necessary in clinical practice and research pertaining to the management of shock. This scoping review summarizes conversion ratios between vasopressors and provides a formula to incorporate into study designs.

A summary of equipotent ratios for common vasopressors used in clinical practice has been provided.

Our formula may be considered to calculate NE for studies in the intensive care unit.

Of 16,315 articles, 21 were included for synthesis.

The range of conversion ratios equivalent to one unit of norepinephrine were: epinephrine (0.7–1.4), dopamine (75.2–144.4), metaraminol (8.3), phenylephrine (1.1–16.3), vasopressin (0.3–0.4) and angiotensin II (0.07–0.13).

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