Optimizing Therapy of Bloodstream Infection Due to Extended-spectrum β-lactamase-producing Enterobacteriaceae
Carbapenems should be used in patients with serious infections; alternatives could be used individually, particularly for definitive treatment of patients with milder presentations. Meropenem and imipenem are the drugs... read more
ED Management of Smoke Inhalation Injury in Adults
When treating patients who have suffered injury in a fire, managing their airway is as critical as treating their burns. Following on the February 2018 issue on Thermal Burns, this issue reviews strategies for diagnosing... read more
Early Prognostication of Neurological Outcome by HRV in Adults with Out-of-Hospital Sudden Cardiac Arrest
The present data indicate that heart rate variability (HRV) analysis could be useful for early prognostication for comatose patients during hypothermic TTM within 24 h after ROSC. The value of HRV as a prognosticator... read more
Neuropharmacotherapy in Critical Illness
The field of research related to neurocritical care has grown significantly in recent years, and the clinical demands for current and dependable expertise has followed suit. It can be a challenge for the neurocritical practitioner... read more
Development and Assessment of Objective Surveillance Definitions for Nonventilator Hospital-Acquired Pneumonia
These findings suggest that objective surveillance for NV-HAP using electronically computable definitions that incorporate common clinical criteria is feasible and generates incidence, mortality, and adjusted ORs for hospital... read more
Why We Sleep: Unlocking the Power of Sleep and Dreams
A New York Times bestseller and international sensation, this stimulating and important book is a fascinating dive into the purpose and power of slumber. Walker is a Professor of Neuroscience and Psychology and the director... read more
ICU Admission Source as a Predictor of Mortality for Patients With Sepsis
Sepsis is the leading noncardiac cause of intensive care unit (ICU) death. Pre-ICU admission site may be associated with mortality of ICU patients with sepsis. This study quantifies mortality differences among patients... read more
Acute Liver Failure: Evidence-Based Evaluation and Management
Although acute liver failure (ALF) is a rare clinical presentation in the ED, it carries a high mortality, morbidity, and resource cost. Across the developing world, the underlying etiology is primarily viral, with hepatitis... read more
Corticosteroids for Children with Septic Arthritis
Researchers conducted a review of the effects of corticosteroids given in addition to antibiotics to children with septic arthritis. Evidence was sought until April 2018. After searching for all relevant studies, reviewers... read more
Impact of a Multifaceted Prevention Program on VAP Including Selective Oropharyngeal Decontamination
Ventilator-associated pneumonia (VAP) remains a serious complication of mechanical ventilation (MV), and has an incidence between 2 and 16 episodes per 1000 ventilator-days, an attributable mortality of 5–13%, excess ICU... read more
Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus
Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. When cIVADs are applied in RSE, prescribing them early... read more
Short-term vs. Conventional Glucocorticoid Therapy in Acute Exacerbations of COPD
In patients presenting to the emergency department with acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD), 5-day treatment with systemic glucocorticoids was noninferior to 14-day treatment with regard to... read more
Presentations from WSD Supporter Meeting at the World Congress of Intensive Care in Melbourne
On Wednesday, October 16th, 2019, World Sepsis Day Supporters from all around the globe came together at the World Congress of Intensive Care in Melbourne, Australia, for a World Sepsis Day Supporter Meeting. Simon Finfer,... read more
First Portable MRI Scanner for Neuro ICU
Health technology incubator Hyperfine Research and the Yale School of Medicine are testing out a first-of-its-kind, portable MRI scanner in the neuro intensive care unit (ICU). The point-of-care system, designed by Hyperfine,... read more
