Critical Care Transport in the Time of COVID-19

Air ambulances and critical care transport providers are operationally-focused organizations that can play a critical role during pandemics. We have provided a short synopsis of our experience during the COVID-19 pandemic... read more

Risk Score for Development of Critical Illness in Patients with COVID-19

In this study, we developed a risk score and web-based calculator to estimate the risk of developing critical illness among patients with COVID-19 based on 10 variables commonly measured on admission to the hospital. Estimating... read more

An ICU Doctor on How We Can Emerge from the Storm Into a Place to Mend

As we emerge from the storm of preparation and uncertainty, where are we now but in a quiet place. A place to mend. A time to dream. For many the effects of lockdown have been devastating; there were never any easy choices... read more

Critical Care Clinician Reports on COVID-19

This national ICU clinician survey indicates that hospitals are expanding ICU bed capacity to prepare for coronavirus disease 2019 patient surge. Importantly, amid this preparation, ICU clinicians harbor concerns regarding... read more

CPR Algorithm Adjustments when Caring for Suspected or Confirmed COVID Cases

When caring for confirmed COVID-19 cases, it is essential for healthcare providers to protect themselves from exposure as best they can. Healthcare providers who contract COVID-19 can increase the burden on an already... read more

Copeptin as a Marker of Outcome After Cardiac Arrest

Copeptin is an independent marker of severity of the post cardiac arrest syndrome, partially related to circulatory failure. 690 patients were included in the analyses, of whom 203 (30.3%) developed cardiovascular deterioration... read more

Preparing ICUs for COVID-19: an Australian Experience

In this article, we describe the response from our intensive care unit (ICU) within a large tertiary private metropolitan Australian hospital. We hope this information may be useful to other ICUs in Australia, for any second... read more

A Mass Casualty In Slow Motion: Emergency Medicine During the COVID-19 Surge in New York City

The first time I really took notice of coronavirus was when a few providers started wearing masks during their shifts. This was in mid-February when the virus was a Wuhan problem, and we were screening people with travel... read more

Hospitals Turn to Remote Monitoring Tools to Free Up Beds for the Sickest COVID-19 Patients

Desperate to free up beds for only the sickest COVID-19 patients, hospitals nationwide are weighing the use of new technologies to monitor patients from their homes. Physicians at several hospitals said their discussions... read more

A Guide To Designing Low-Cost Ventilators for COVID-19

The best medical treatment currently for COVID-19 is to simply assist the lung function with mechanical ventilation. Unfortunately hospitals are experiencing such huge influx of patients and do not have enough ventilators. This... read more

Can COVID-19 Cause Sepsis? Coronavirus Disease and Sepsis Relationship

On January 30th, the World Health Organization declared the 2019 Novel Coronavirus (SARS-CoV-2) a global health emergency, declaring it an "unprecedented outbreak." While the fears of a COVID-19 pandemic are legitimate,... read more

Use of Supraglottic Airways During COVID-19 Pandemic

This document is produced in response to questions about the use of supraglottic airways (SGAs) during the current pandemic. The advice that it contains is based on the expert opinion of airway specialists and is meant to... read more

Respiratory Physiology of Mechanically Ventilated Patients with COVID-19

In this "Breathe Easy Critical Perspective" podcast, Dr. Dominique Pepper interviews Drs. Jehan Alladina and Corey Hardin. They discuss the respiratory physiology of mechanically ventilated patients with COVID-19. Dr.... read more

In the Fight to Treat Coronavirus, Your Lungs Are a Battlefield

Ventilators have become the single most important piece of medical equipment for critically ill coronavirus patients whose damaged lungs prevent them from getting enough oxygen to vital organs. The machines work by forcing... read more

Acute Respiratory Failure in COVID-19: Typical ARDS?

COVID-19 is highly infectious and can lead to fatal comorbidities especially ARDS. There are currently no recommended specific anti-COVID-19 treatments, so supportive treatment is important. Fully understanding the characteristics... read more

Prevention and Treatment of ALI with Time-controlled Adaptive Ventilation

Neither the current lung protect and rest nor open lung approach (OLA) ventilation strategies have been effective at reducing VILI and ARDS-related mortality below that in the ARMA study. For a protective ventilation strategy... read more

Awake Proning for COVID-19

Prone positioning improves oxygenation in spontaneous breathing nonintubated patients with hypoxemic acute respiratory failure: A retrospective study. This is a retrospective case series describing 15 non-intubated patients... read more

High Risk of Thrombosis in Patients with Severe COVID-19

Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more

Rapid Development of an Inactivated Vaccine Candidate for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more

The Pandemic Is a Perfect Storm for ICU Delirium

Spending time in the ICU, especially for anyone with COVID-19, is a dangerous, physically taxing experience: Only the most seriously ill patients land in intensive care, where many undergo a number of complex medical treatments... read more

Pathological Inflammation in Patients with COVID-19

The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease... read more

Provider Burnout and Fatigue During the COVID-19 Pandemic

The novel Coronavirus Disease 2019 (COVID-19) pandemic has resulted in an overall surge in new cases of depression and anxiety and an exacerbation of existing mental health issues, with a particular emotional and physical... read more