The Fallacy of Time-to-Intervention Studies
We are barraged by time-to-intervention studies (door-to-balloon time, time-to-antibiotics, door-to-needle, etc.). However, it must be kept in mind that these studies are purely correlational in design. Such studies cannot... read more
Both Nurse Practitioners and Physicians Should be Outraged
The United States is facing a looming physician shortage, and some groups see this as an opportunity to promote an agenda of replacing physicians with nurses. The nurse-as-doctor concept appeared in the Institute of Medicine... read more
Pediatric Critical Care, 5e
Still the #1 resource for today's pediatric ICU teams, the newly released Pediatric Critical Care, 5th Edition covers the entire field, from basic science to cutting-edge clinical applications. Drs. Bradley P. Fuhrman and... read more
Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the ICU
The UW-IPASS standardized handoff curriculum was perceived to improve intensive care provider preparedness and workflow. IPASS-based curricula represent an important step forward in communication standardization efforts and... read more
Development of Dementia in Patients with Femoral Neck Fracture Who Experience Postoperative Delirium
It remains unclear to what extent postoperative delirium (POD) affects the incidence of dementia in hip fracture patients, and the methods used to detect delirium and dementia require validation. The aim of this study was... read more
The Way We Think About Nurse Burnout is Broken
There are several things wrong with the way we think about nurse burnout. This is troubling for several reasons. If we do not have a clear understanding about burnout, then we cannot help nurses who may be suffering from... read more
Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness
Long-term cognitive impairment is common in survivors of critical illness. Little is known about the etiology of this serious complication. We sought to summarize current scientific knowledge about potentially modifiable... read more
TAC on Computed Tomography and the Risk of COPD Progression
Total Airway Count (TAC) may reflect the airway-related disease changes that accumulate in the “quiet” zone in early/mild Chronic Obstructive Pulmonary Disease (COPD), indicating that TAC acquired with commercially available... read more
Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock
The guideline recommendations showed that shorter delays indicates better outcomes. There was no evidence that 3 hours is safe; even very short delays adversely impact outcomes. Findings demonstrated a new approach to incorporate... read more
A Digital Revolution in Health Care is Speeding Up
Telemedicine, predictive diagnostics, wearable sensors and a host of new apps will transform how people manage their health. In the longer term, the biggest upheaval may come from the large technology firms. Amazon and Google... read more
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery. Among patients predominantly undergoing abdominal surgery who... read more
A Thousand Naked Strangers: A Paramedic’s Wild Ride to the Edge and Back
A former paramedic's visceral, poignant, and mordantly funny account of a decade spent on Atlanta's mean streets saving lives and connecting with the drama and occasional beauty that lies inside catastrophe. In the aftermath... read more
Severity of Illness Scores May Misclassify Critically Ill Obese Patients
Severity of illness scores rest on the assumption that patients have normal physiologic values at baseline and that patients with similar severity of illness scores have the same degree of deviation from their usual state.... read more
Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients
This Bayesian network meta-analysis demonstrated the comparative effectiveness of fifteen antimicrobial treatments for drug-resistant A. baumannii pneumonia in critically ill patients. For survival benefit, SUL appears to... read more
Hospitalist Tackles Chronic Disease With Food Pharmacies
Before January 2017, Rita Nguyen, MD, was "pretty much like any other academic hospitalist," she says. In the hospital, she could provide excellent care to patients, but once they were discharged, many didn't have the necessary... read more
The Contents of a Patient Diary and its Significance in the ICU
The aim of this study was to describe the contents of a patient diary and its significance for persons cared for in an ICU. What formerly critically ill patients appreciate most about the diary is that the diary is personally... read more
Urine Test Developed to Test for Tuberculosis
An international team of researchers has developed a urine test that can be used to detect tuberculosis (TB) in human patients. Alessandra Luchini and her team have developed a urine test for TB that gives results in 12 hours.... read more
The Flu Is Already Widespread in 36 States
Flu season has kicked off in full force, with the Centers for Disease Control and Prevention (CDC) reporting Friday that influenza is already widespread in 26 states across the U.S. The peak of the flu season typically comes... read more
Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation
Almost all patients with pulmonary bilateral infiltrates and a PaO2/FIO2 less than or equal to 300 mm Hg under standard oxygen fulfilled the acute respiratory distress syndrome criteria under noninvasive ventilation within... read more
A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality
Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more
Effect of Lung Recruitment and Titrated PEEP vs Low PEEP on Mortality in Patients with ARDS
In patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS), a strategy with lung recruitment and titrated Positive End-Expiratory Pressure (PEEP) compared with low PEEP increased 28-day all-cause mortality.... read more
Early goal-directed nutrition in ICU patients (EAT-ICU)
Extensive weight loss has been documented in intensive care unit (ICU) survivors, primarily as the result of muscle loss, leading to impaired physical function and reduced quality of life. The aim of the EAT-ICU trial is... read more
