4m-gait speed test reliable/valid physical function measure in ARDS survivors
The 4-m gait speed is a reliable, valid, and responsive measure of physical function in acute respiratory distress syndrome survivors. The estimated minimal important difference will facilitate sample size calculations for... read more
Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults
Between Feb 6, 2014, and June 26, 2016, 1360 patients were assessed, and 672 were randomly assigned, with 222 in the placebo group, 227 in the 0·5 mg/kg ketamine group, and 223 in the 1·0 mg/kg ketamine group. There was... read more
A multicenter, randomized trial of a checklist for endotracheal intubation of critically ill adults
The verbal performance of a written, pre-procedure checklist does not increase the lowest arterial oxygen saturation or lowest systolic blood pressure during endotracheal intubation of critically ill adults compared to usual... read more
Non-medical Pediatric Supplies for Puerto Rico
Society of Critical Care Medicine (SCCM) set up a special Amazon account for non-medical supplies, such as diapers, baby clothing, hand sanitizer and other items, that have run out in pediatric intensive care units. Items... read more
Effect of Systematic ICU Triage on Long-term Mortality Among Critically Ill Elderly Patients
Among critically ill elderly patients in France, a program to promote systematic ICU admission increased ICU use but did not reduce 6-month mortality. Additional research is needed to understand the decision to admit elderly... read more
Addressing Antimicrobial Resistance and Stewardship
Antimicrobial-resistant infections affect more than 2 million people annually in the United States alone, accounting for an estimated 23 000 deaths and estimated economic costs of $55 billion. Recent projections suggest... read more
The Business Case for Investing in Physician Well-being
Understanding the business case to reduce burnout and promote engagement as well as overcoming the misperception that nothing meaningful can be done are key steps for organizations to begin to take action. Evidence suggests... read more
Cellular Immunotherapy for Septic Shock
The infusion of freshly cultured allogenic bone marrow derived MSCs into participants with septic shock up to a dose of 3 million cells per kg (250 million cells) appears safe. Ages of participants in the interventional versus... read more
The House of God
The House of God is a mesmerizing and provocative novel about Roy Basch and five of his fellow interns at the most renowned teaching hospital in the country. A phenomenon ever since it was published, The House of God was... read more
Clinical Review: Paracetamol in fever in critically ill patients
Paracetamol is a synthetic, nonopioid, centrally acting analgesic and antipyretic drug. Its antipyretic effect occurres because it inhibits cyclooxygenase-3 and the prostaglandin synthesis.... read more
Cytomegalovirus infection in immunocompetent critically ill adults
Some studies have demonstrated an association between Cytomegalovirus (CMV) disease and increased mortality rates, prolonged intensive care unit and hospital length of stay, prolonged mechanical ventilation, and nosocomial... read more
Traditional vs. Extended Cefepime Infusion in Critically Ill Patients
Patients with Pseudomonas aeruginosa bacteremia or pneumonia had a reduced 28-day all-cause mortality and length of stay in the ICU when administered an extended infusion of cefepime.... read more
First Year in Care Critical to Retention, HIV Suppression
A previous study showed that the rate of long-term mortality more than doubled when patients missed visits in the first year after diagnosis.... read more
Anesthesia changes neuronal choreography
Even under deep anesthesia, nerve cells remain highly active. A study conducted by researchers from Charite - Universitätsmedizin Berlin has shown by high-resolution cellular imaging that local neuronal networks remain active... read more
Face Mask vs Helmet for Noninvasive Ventilation
In Reply Drs Taccone and Chiumello state that physicians must understand the helmet’s physiologic behavior in terms of CO2 rebreathing to ensure safety. Neurological impairment led to intubation in 5 of the 8 intubated... read more
Systematic review suggests synovial fluid analysis when necessary for diagnosis of gout
Gout presents with acute attacks of synovitis that start out as intermittent but can advance to chronic symptoms.... read more
Efficacy of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation
This study demonstrates that Shenfu injection in combination with conventional postresuscitation care bundle treatment is effective at improving clinical outcomes in patients with return of spontaneous circulation after in-hospital... read more
Principles of Antimicrobial Stewardship for Bacterial and Fungal Infections in ICU
Selecting antimicrobial therapy for suspected infection in critically ill patients is an important decision-making process for intensivists. In this current age of multi-drug-resistant organisms (MDROs), intensivists must... read more
Antiseptic baths to prevent infections deemed effective for long-term use
Long-term use antiseptic soap in bathing critically ill patients to prevent healthcare-associated infections (HAIs) did not cause high levels of resistance in bacteria on the patients' skin.... read more
Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery
Sodium nitroprusside (SNP) has been used clinically for decades for the treatment of hypertension associated with cardiac surgery.... read more
Hospital-Readmission Risk – Isolating Hospital Effects from Patient Effects
When the same patients were admitted with similar diagnoses to hospitals in the best-performing quartile as compared with the worst-performing quartile of hospital readmission performance, there was a significant difference... read more
