Pilot Feasibility Study of Therapeutic Hypothermia for Moderate to Severe ARDS
Neuromuscular blockade alone does not cause hypothermia but allowed acute respiratory distress syndrome patients to be effectively cooled. Results support conducting a randomized clinical trial of hypothermia in acute respiratory... read more
Safety of MRI in Patients with Cardiac Devices
Patients who have pacemakers or defibrillators are often denied the opportunity to undergo magnetic resonance imaging (MRI) because of safety concerns, unless the devices meet certain criteria specified by the FDM. We evaluated... read more
Elevated BNP Levels in CFS Associated with Cardiac Dysfunction
This study confirms an association between reduced cardiac volumes and brain natriuretic peptide (BNP) in chronic fatigue syndrome (CFS). Lack of relationship between length of disease suggests that findings are not secondary... read more
Clinicians’ Expectations of the Benefits and Harms of Treatments, Screening, and Tests
Clinicians rarely had accurate expectations of benefits or harms, with inaccuracies in both directions. However, clinicians more often underestimated rather than overestimated harms and overestimated rather than underestimated... read more
Bleeding During Percutaneous Dilatational Tracheostomy – What to do while waiting for the surgeon?
A patient suffered significant bleeding during an attempt at percutaneous dilatational tracheostomy due to an aberrant anterior jugular vein. Bleeding was controlled with pressure temporarily, but quickly returned necessitating... read more
Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants
In this randomized clinical trial that included 470 patients who were undergoing surgery for removal of orthopedic implants used for treatment of below-the-knee fractures, surgical site infection occurred in 12.9% of patients... read more
The Iatrogenic Potential of the Physician’s Words
Some of the information that physicians convey to their patients can inadvertently amplify patients' symptoms and become a source of heightened somatic distress, an effect that must be understood by physicians to ensure optimal... read more
Fifty Years of Research in ARDS
Mechanical ventilation (MV) is critical in the management of many patients with acute respiratory distress syndrome (ARDS). However, MV can also cause ventilator-induced lung injury (VILI). The selection of an appropriate... read more
Development and Validation of an Empiric Tool to Predict Favorable Neurologic Outcomes Among PICU Patients
This proposed prediction tool encompasses 20 risk factors into one probability to predict favorable neurologic outcome during ICU stay among children with critical illness. Future studies should seek external validation and... read more
Doctor & Scientist Running for Congress
I worked for CDC: the 7 "banned words" are just the beginning... When I heard the recent news - that CDC experts have been banned or discouraged by the Trump administration from using key words, including "evidence-based"... read more
A Research Agenda for Communication Between Health Care Professionals and Patients Living With Serious Illness
Poor communication by health care professionals contributes to physical and psychological suffering in patients living with serious illness. Patients may not fully understand their illness, prognosis, and treatment options... read more
Burnout and Stress Among US Surgery Residents
Burnout among physicians affects mental health, performance, and patient outcomes. Surgery residency is a high-risk time for burnout. We examined burnout and the psychological characteristics that can contribute to burnout... read more
Dexmedetomidine-Associated Hyperthermia
Dexmedetomidine-associated hyperthermia: a retrospective cohort study of intensive care unit admissions between 2009 and 2016. Dexmedetomidine-associated hyperthermia has not been previously studied. Analysis is warranted... read more
Current Therapy of Trauma and Surgical Critical Care
A comprehensive and contemporary summary of the treatment and post-operative management of traumatic injuries. The concise format makes it ideally suited for everyday use, and new, full-color illustrations highlight the most... read more
Top 10 Critical Care Trials for 2017
We held a poll within our editorial group, rating all 36 of the published trials from 2017 that we have summarised and critiqued. We considered the importance of the clinical question, how game changing the conclusion was... read more
Regional Variation of Computed Tomographic Imaging and the Risk of Nephrectomy
In this analysis of 306 hospital referral regions, regional CT risk was significantly correlated with nephrectomy, and scanning an additional 1000 Medicare beneficiaries was associated with 4 additional nephrectomies. Beneficiaries... read more
How Big Tech Is Going After Your Health Care
When Daniel Poston, a second-year medical student in Manhattan, opened the App Store on his iPhone a couple of weeks ago, he was astonished to see an app for a new heart study prominently featured. People often learn about... read more