New Blood Draw Protocol can reduce risks for pediatric patients
Researchers report that implementing a checklist-style set of procedures appears to cut almost in half the number of potentially unnecessary blood culture draws in critically ill children without endangering doctors'... read more
Professor Wins Outstanding Investigator Award for Lung Disease Antioxidant Studies
The National Heart, Lung and Blood Institute (NHLBI) has named the recipient of its inaugural Outstanding Investigator Award: Yvonne Janssen-Heininger, PhD, professor of pathology and laboratory medicine at the Larner College... read more
Seizures Prior to Diagnosis of Tuberous Sclerosis Complex
Seizures were a condition commonly experienced by patients prior to diagnosis of TSC; understanding the initial diagnoses experienced by TSC patients may help lead to earlier diagnosis and treatment of TSC. Many patients... read more
Better Skin Grafts After Research on Sweat Glands
Scientists at Rockefeller University have identified the molecular underpinnings that guide the formation of both hair follicles and sweat glands, finding that two opposing signaling pathways, which can suppress one other,... read more
Disease Causation Index Established By New Mathematical Model
Patients with complex diseases have a higher risk of developing another. Multi-morbidity represents a huge problem in everyday clinical practice, because it makes it more difficult to provide successful treatment. By analysing... read more
New Study on Molecular Mechanisms Involved in RILF
Reversible infantile liver failure (RILF) is a heritable mitochondrial condition that causes severe liver dysfunction in infancy, but those who survive the acute stage typically recover and have no further problems. In work... read more
The CAPCRI study on Semi-recumbent positioning
The CAPCRI study(3) conducted by Mireia Llaurado and her team had three aims: to evaluate real semi-recumbent position compliance and degree of head-of-bed elevation in Spanish intensive care units, to describe the relationship... read more
Tackling Antimicrobial Resistance
Antimicrobial resistance happens when bugs, like bacteria, fungi or viruses, change, or evolve, when they’re exposed to drugs, like antibiotics, antifungals, or antivirals. Bugs that develop antimicrobial resistance are... read more
Epstein-Barr risk increased by Immune Molecule Deficiency
Researchers from the National Institutes of Health National Institute of Allergy and Infectious Diseases, or NIAID, have found a genetic immune disorder causing increased risk and poor control of Epstein-Barr virus and EBV-associated... read more
Induced hypothermia not associated with better outcomes for status epilepticus
In this trial, induced hypothermia added to standard care was not associated with significantly better 90-day outcomes than standard care alone in patients with convulsive status epilepticus.... read more
Serum biomarker associated with metformin dosing or use
The growth differentiation factor 15 (GDF15) is a novel biomarker for the use and dosing of metformin, according to a study published online Dec. 14 in Diabetes Care. 237 serum biomarkers from participants in the Outcome... read more
Study shows Tumor cells move differently than normal cells
Drexel University researchers have found that some tumor cells are unable to move like healthy cells, which could impact the way cancer is spread and treated. The team found that certain tumor cells called fibrosarcoma cannot... read more
Outsourced Hospital Cleaning linked to MRSA
Analysis of English NHS hospitals suggests that employing private as opposed to in-house cleaners is a false economy. While it may reduce costs, it could also raise risk of infection by methicillin-resistant Staphylococcus... read more
Clinical challenge in IBD expanded by Systemic inflammation
More targeted antibody therapies carry the potential to transform how physicians treat inflammatory bowel disease. However, management can become less clear when IBD patients present with extra-intestinal manifestations.... read more
Think Sepsis and Act Fast
New attention to sepsis including revised definitions, updated guidelines, and new CMS reporting requirements aims to save lives through prevention and prompt and effective management of infections. CDC released a new Vital... read more
Different Rest Intervals in Low-load Resistance Training
Acute hormonal responses, as well as chronic changes in muscle hypertrophy and strength in low-load training to failure are independent of the rest interval length.... read more
How nurses support families of ICU patients towards the end of life
Researchers gathered evidence on how nurses care for patients and their families in intensive care when life-sustaining treatment is withdrawn. The included studies explored the care of the family before, during and after... read more
Blood culture decision algorithm tied to PICU admissions
A standardized approach to blood cultures in the pediatric ICU successfully reduced collections from central venous catheters, investigators at a single center reported, with no subsequent uptick in adverse events.... read more
Bacteriophages may harbor antibiotic resistance genes
Scientists at the Catalan Institute for Water Research have carried out a comprehensive analysis of several viromes from different habitats to explore whether bacteriophages (viruses that infect bacteria) harbor antibiotic... read more
Here is Why COPD Disrupts Lung-Repair Ability
In chronic obstructive pulmonary disease (COPD), the patients' lungs lose their ability to repair damage on their own. Scientists at the Helmholtz Zentrum München, partner in the German Center for Lung Research, now... read more
