Traditional vs. Extended Cefepime Infusion in Critically Ill Patients
Patients with Pseudomonas aeruginosa bacteremia or pneumonia had a reduced 28-day all-cause mortality and length of stay in the ICU when administered an extended infusion of cefepime.... read more
First Year in Care Critical to Retention, HIV Suppression
A previous study showed that the rate of long-term mortality more than doubled when patients missed visits in the first year after diagnosis.... read more
Anesthesia changes neuronal choreography
Even under deep anesthesia, nerve cells remain highly active. A study conducted by researchers from Charite - Universitätsmedizin Berlin has shown by high-resolution cellular imaging that local neuronal networks remain active... read more
Face Mask vs Helmet for Noninvasive Ventilation
In Reply Drs Taccone and Chiumello state that physicians must understand the helmet’s physiologic behavior in terms of CO2 rebreathing to ensure safety. Neurological impairment led to intubation in 5 of the 8 intubated... read more
Systematic review suggests synovial fluid analysis when necessary for diagnosis of gout
Gout presents with acute attacks of synovitis that start out as intermittent but can advance to chronic symptoms.... read more
Efficacy of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation
This study demonstrates that Shenfu injection in combination with conventional postresuscitation care bundle treatment is effective at improving clinical outcomes in patients with return of spontaneous circulation after in-hospital... read more
Principles of Antimicrobial Stewardship for Bacterial and Fungal Infections in ICU
Selecting antimicrobial therapy for suspected infection in critically ill patients is an important decision-making process for intensivists. In this current age of multi-drug-resistant organisms (MDROs), intensivists must... read more
Antiseptic baths to prevent infections deemed effective for long-term use
Long-term use antiseptic soap in bathing critically ill patients to prevent healthcare-associated infections (HAIs) did not cause high levels of resistance in bacteria on the patients' skin.... read more
Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery
Sodium nitroprusside (SNP) has been used clinically for decades for the treatment of hypertension associated with cardiac surgery.... read more
Hospital-Readmission Risk – Isolating Hospital Effects from Patient Effects
When the same patients were admitted with similar diagnoses to hospitals in the best-performing quartile as compared with the worst-performing quartile of hospital readmission performance, there was a significant difference... read more
Maryland emergency doctors find new life-saving use in old machine
A little used machine designed to detox people who overdose on Tylenol and other medications found another use. Doctors at Shock Trauma used it to save a teenage gunshot victim and then a college football player and an amateur... read more
Prehabilitation: Preparing Patients for Surgery
The impact of surgery leads to significant homeostatic disturbance.1 The surgical stress response is characterised by catabolism and increased oxygen demand. The extent and duration of the stress response is proportionate... read more
Sepsis – Explained in 3 Minutes
Sepsis is an emergency, striking about 30 million people every year, killing 6 to 9 million of them. Learn what sepsis is, and how to identify and treat it in this 3-min video. Please share with your loved ones - it could... read more
Can Early Rehabilitation on the General Ward After an ICU Stay Reduce Hospital Length of Stay in Survivors of Critical Illness?
An early rehabilitation program in survivors of critical illness led to an earlier discharge from the hospital, improved functional recovery, and was also cost-effective and safe. In the per-protocol analysis, length of... read more
Steroids for severe CAP. Should I?
Steroids. I always have mixed feelings about them. It's a Love & Hate relationship inside my head. On one hand I cannot stand those who claim steroids are the critical care's Holy Grail. Steroids for sepsis, ARDS, trauma,... read more
A comparison of two insulin infusion protocols in the ICU by continuous glucose monitoring
The Yale protocol provided better average glycemia, more time spent in normoglycemia, less time in hypoglycemia, and less glycemic variability than the Leuven protocol, but was not independently associated with strict glycemic... read more
