USPSTF: Don’t Screen Asymptomatic Adults for Thyroid Cancer
After reviewing studies on the benefits and harms of screening and treatment for thyroid cancer, a newly released U.S. Preventive Services Task Force draft statement recommends against screening asymptomatic adults for the... read more
Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome
Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more
Apnoeic oxygenation via high-flow nasal cannula oxygen combined with non-invasive ventilation preoxygenation for intubation in hypoxaemic patients in the intensive care unit
A novel strategy for preoxygenation in hypoxaemic patients, adding HFNC for apnoeic oxygenation to NIV prior to orotracheal intubation, may be more effective in reducing the severity of oxygen desaturation than the reference... read more
Lower threshold for abdominal aortic aneurysm repair linked to reduced mortality
The study examined the differences between the threshold of repair and aneurysm-related mortality in England and the United States. The rate of hospitalization due to a ruptured aneurysm and aneurysm-related death was significantly... read more
New anti-inflammatory drug reduces death of existing brain cells then repairs damage after stroke
Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage.... read more
Successfully treating genetically determined autoimmune enteritis
Using targeted immunotherapy, doctors have succeeded in curing a type of autoimmune enteritis caused by a recently discovered genetic mutation.... read more
Stroke: New drug limits brain damage and promotes repair
Research using rats shows a drug already approved for other conditions reduces the number of brain cells killed by stroke and promotes birth of new ones.... read more
How to prevent spread of the skin infection impetigo
Impetigo is a contagious skin infection that's preventable and can be treated with antibiotics, the U.S. Food and Drug Administration says. Impetigo can strike anytime but is more common during warm weather months. More... read more
Puerto Rico reports nearly 500 new Zika cases amid epidemic
Puerto Rico's health secretary says nearly 500 new cases of Zika have been reported in the U.S. territory in the past week. 34,562 cases of the mosquito-borne virus have now been registered.... read more
Limited predictability of maximal muscular pressure using the difference between peak airway pressure and positive end-expiratory pressure during proportional assist ventilation (PAV)
Deducing maximal muscular pressure from ΔP during PAV has limited accuracy. The extrapolated pressure time product from ΔP is usually less than the pressure time product calculated from oesophageal pressure tracing.... read more
Researchers developing biomaterial with potential to treat vascular bleeding
Researchers at Mayo Clinic, Harvard Medical School and the Massachusetts Institute of Technology are developing a biomaterial that has potential to protect patients at high risk for bleeding in surgery.... read more
New method for predicting congenital congenital cytomegalovirus infection during the prenatal period
Congenital cytomegalovirus (CMV) infection can cause serious complications such as hearing difficulties and mental delay in affected infants. A research team has discovered a new method for predicting congenital CMV infection... read more
Targeted Drug Delivery using Porous Glass Microspheres
Finding ways to improve efficiency and bioavailability is key to targeted drug delivery. Although controlled release dosage medication forms are the standard, they can have certain limitations.... read more
Risk of hemorrhage with statins and stroke prevention drug combination
Two commonly used statins can increase the risk of hemorrhage when combined with dabigatran etexilate, a drug often used for preventing stroke in patients with atrial fibrillation.... read more
Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation
Ten trials met the inclusion criteria for this review (n = 1658 participants). We found five trials to be at low risk of bias and five to be at moderate risk of bias.... read more
Coma with Eelco Wijdicks – Podcast
So you have an unresponsive patient. The CT is negative. What now? Coma is tough! The differential is long and filled with many life threats.... read more
Acute Flaccid Myelitis Outbreak in Washington
There has been a recent spike of cases reported in five counties in Washington State, in which eight children have been hospitalized for Acute Flaccid Myelitis.... read more
What a hospital bed could teach about patient safety
Most hospitalized patients spend the vast majority of their time in a hospital bed. Any body fluids such as blood, feces, urine, stomach contents, etc. that are secreted come in direct contact with that hospital bed.... read more
Negative pressure irrigation and endoscopic necrosectomy through man-made sinus tract in infected necrotizing pancreatitis
This four-step approach is effective in treating IPN and adds no extra risk to patients when compared with other latest step-up strategies. The two novel techniques (NPI and ED) could offer distinct clinical benefits without... read more
Children in ICU recover faster without nutrition
Researchers in Belgium found the standard practice of feeding children as soon as they get to ICU to help them recover faster is wrong.... read more
Vasopressin vs. norepinephrine for vasoplegic shock after cardiac surgery
Patients in the VANISH trial treated with vasopressin had a lower incidence of renal failure requiring hemodialysis. However, this was a secondary endpoint which seemed to contradict the primary endpoint (defined as a milder... read more
