Examining Pantoprazole or Placebo for Stress Ulcer Prophylaxis
Pantoprazole is frequently administered to critically ill patients for prophylaxis against gastrointestinal bleeding. However, comparison to placebo has been inadequately evaluated, and pantoprazole has the potential to cause... read more
Benefits of PCI for STEMI Not Attenuated in Patients With a Cancer History
Having a history of cancer does not worsen outcomes for patients with STEMI who undergo primary PCI and should not be a barrier to revascularization and optimal therapy.... read more
Care of the eye during anaesthesia and intensive care
Perioperative eye injuries and blindness are rare but important complications of anaesthesia. The three causes of postoperative blindness are ischaemic optic neuropathy, central retinal artery thrombosis.... read more
Scientists create first viable mathematical model of a key anti-Salmonella defense system
Scientists have created the first validated mathematical model of an important cellular defense mechanism against the bacterium Salmonella, according to a new study in PLOS Computational Biology.... read more
Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches
Todd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz... read more
Palliative care intervention improves quality of life during hospitalization for hematopoietic stem cell transplantation
Palliative care involvement helps lessen quality of life (QOL) decline compared to standard care during hospitalization for hematopoietic stem cell transplantation.... read more
Hypernatremia (Uggggh!)
Hyponatremia has become a little bit sexy. Not so with sodium that is too high. But I’ve seen a bunch of less than ideal management of hypernatremia, so I figured it is time to put out a podcast about it.... read more
Physicians at RSNA make case for contrast enhanced ultrasound
The procedure, which was OK'd by the FDA this year for liver screening, but is currently not approved in the U.S. for cardiac disease shows particular value in imaging children who may otherwise have to undergo a CT... read more
Healthcare Providers and Exercise Specialists Struggle With Prescribing Physical Activity
TCTMD asked cardiovascular health professionals how they approach the challenge of prescribing physical activity, their answers may surprise you.... read more
Value of Expedited Drug Approvals for Cancer Care
This study examines potential benefits of cancer drugs approved by the FDA on the basis of surrogate endpoints.... read more
USPSTF: Don’t Screen Asymptomatic Adults for Thyroid Cancer
After reviewing studies on the benefits and harms of screening and treatment for thyroid cancer, a newly released U.S. Preventive Services Task Force draft statement recommends against screening asymptomatic adults for the... read more
Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome
Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more
Apnoeic oxygenation via high-flow nasal cannula oxygen combined with non-invasive ventilation preoxygenation for intubation in hypoxaemic patients in the intensive care unit
A novel strategy for preoxygenation in hypoxaemic patients, adding HFNC for apnoeic oxygenation to NIV prior to orotracheal intubation, may be more effective in reducing the severity of oxygen desaturation than the reference... read more
Lower threshold for abdominal aortic aneurysm repair linked to reduced mortality
The study examined the differences between the threshold of repair and aneurysm-related mortality in England and the United States. The rate of hospitalization due to a ruptured aneurysm and aneurysm-related death was significantly... read more
New anti-inflammatory drug reduces death of existing brain cells then repairs damage after stroke
Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage.... read more
Successfully treating genetically determined autoimmune enteritis
Using targeted immunotherapy, doctors have succeeded in curing a type of autoimmune enteritis caused by a recently discovered genetic mutation.... read more