Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis
Bacterial sepsis patients had early, severe inflammation, profound immune suppression, and life-threatening organ dysfunction that resolved over time; SARS-CoV-2 patients had less severe early inflammation and organ dysfunction... read more
Case-Based Device Therapy for Heart Failure
This book provides a comprehensive practical guide to the plethora of devices that have been developed to support the failing heart. It features easy to follow clinically relevant guidance on mechanical devices used for improving... read more
Predicting Sepsis Severity at First Clinical Presentation
The severity and endotype signatures indicate that distinct immune signatures precede the onset of severe sepsis and lethality, providing a method to triage early sepsis patients. Gene expression signatures were obtained... read more
Advanced Hemodynamic Monitoring: Basics and New Horizons
This book describes how to monitor and optimize cardiovascular dynamics using advanced hemodynamic monitoring in perioperative and intensive care medicine. The book outlines basic skills of hemodynamic monitoring, different... read more
Resuscitation Using ECPR During In-Hospital Cardiac Arrest Mortality Prediction Score
The RESCUE-IHCA score can be used by clinicians in real time to predict in-hospital death among patients with in-hospital cardiac arrest (IHCA) who are treated with extracorporeal cardiopulmonary resuscitation (ECPR). A... read more
Intravenous Vitamin C Administration to Septic Shock Patients
Our pilot study indicated that intravenous vitamin C did not provide significant decreases in the mean dose or duration of vasopressor infusion. Further research that takes into account the potential impact of intervention... read more
Physics for Anesthesiologists and Intensivists: From Daily Life to Clinical Practice
This book, now in its 2nd edition, discusses, explains and provides detailed, up-to-date information on physics applied to clinical practice in anesthesiology and critical care medicine, with the aid of simple examples from... read more
Physiologically Difficult Airway Evaluation
Multiple international airway societies have created guidelines for the management of the difficult airway. In critically ill patients, there are physiologic derangements beyond inadequate airway protection or hypoxemia.... read more
ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models
Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies... read more
Long-term Cardiovascular Outcomes of COVID-19
The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used... read more
Coupled Plasma Filtration and Adsorption for Septic Shock Treatment
Early deaths are likely related to the ongoing CPFA treatment, for reasons that if identified could allow some deaths to be prevented. We hypothesize a connection to hemodynamic instability consequent on renal replacement... read more
Guidelines on Temperature Control After Cardiac Arrest in Adults
The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are coma‑tose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying... read more
Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China
There was nonlinear relationship between fluid balance and all three tiers of ventilator-associated event, with an fluid balance between –1 and 0 L corresponding to the lowest risk. Positive but not negative fluid balance... read more
Impact of Frailty on Persistent Critical Illness
Compared to patients without frailty, those with frailty have a higher chance of developing and dying from Persistent Critical Illness (PerCI). Moreover the importance of frailty as a predictor of mortality increases with... read more
