Ultrasound-Guided Infraclavicular Axillary Vein vs. Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients

No difference was found between the real-time ultrasound-guided out-of-plane cannulation of the IJV and the infraclavicular real-time ultrasound-guided in-plane cannulation of the AXV. Both techniques are equally efficient... read more

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

The study evaluated the use of heart rate variability (HRV) to predict the outcome of patients in the ICU. HRV is a way to evaluate the cardiac effects of the autonomic nervous system, and a relation between HRV and outcome... read more

A Young Doctor’s Perspective Was Forever Changed by ICU Experience

A healthy 30-year-old doctor had an unexpected medical emergency while preparing for a procedure, which led to the discovery of a small hemorrhage in her dorsal brainstem. She was transferred to the neuro ICU and experienced... read more

Acute Effects of Ketamine on ICP in Children With Severe TBI

In this retrospective, exploratory study, intracranial pressure (ICP) did not increase following ketamine administration. In the setting of a guidelines-based protocol, ketamine was associated with a reduction in ICP during... read more

Baricitinib or Tocilizumab for Severe COVID-19 Treatment

Pharmacologic treatment of COVID-19 has continued to evolve since the onset of the pandemic, and yet many questions remain about optimal treatment. Medicine strives to provide evidence-based guidance on treatments, but... read more

A Guide to Mechanical Circulatory Support: A Primer for Ventricular Assist Device (VAD) Clinicians

This unique book details a multidisciplinary approach for providers caring for the Mechanical Circulatory Support (MCS) patient. Authors discuss the history of MCS, patient selection, surgical and post-operative care, mobility... read more

A Guide to Mechanical Circulatory Support: A Primer for Ventricular Assist Device (VAD) Clinicians

6 Days Higher-Dose Ivermectin vs. Placebo on Time to Sustained Recovery in COVID-19 Outpatients

Among a largely vaccinated outpatient population with mild to moderate COVID-19, treatment with ivermectin, with a targeted maximum dose of 600 μg/kg daily for 6 days, compared with placebo was not shown to improve time... read more

I Was a Doctor Through COVID. Then One Case Pushed Me Over the Edge

On some days I can almost forget that COVID ever happened. The old rhythms of the ICU at University College London, where I am a consultant in critical care and anesthesia, have returned. The bed pressures, the worrying cases,... read more

Extracorporeal Membrane Oxygenation for Adults (Respiratory Medicine)

This new edition presents an evidence-based review of extracorporeal membrane oxygenation (ECMO) for adults, with a particular focus on veno-venous (VV) ECMO. Due to the dramatic impact of COVID-19, the number of institutions... read more

Extracorporeal Membrane Oxygenation for Adults (Respiratory Medicine)

The effect of a multi-faceted quality improvement program on paramedic intubation success in the critical care transport environment

A multi-faceted advanced airway management (AAM) quality improvement program (QIP) resulted in statistically significant increase in intubation first pass success rates (FPS) rates and a non-significant improvement in DASH-1A... read more

Intracranial Pressure: Current Perspectives on Physiology and Monitoring

Intracranial pressure (ICP) monitoring is now viewed as integral to the clinical care of many life-threatening brain insults, such as severe traumatic brain injury, subarachnoid hemorrhage, and malignant stroke. It serves... read more

Trauma Group Publishes Action Plan, Makes Data Available for Secondary Analyses

The American College of Surgeons (ACS) has long advocated for the creation of a US National Trauma System to improve quality of care, decrease inequities, and save lives as one of its top legislative priorities, part of which... read more

Neuromonitoring in the Neonatal ECMO Patient

Utilization of extraocorporeal membrane oxygenation (ECMO) has become increasingly widespread as a bridging therapy for neonates with severe, reversible respiratory or cardiac diseases. While significant risks remain, due... read more

ECMO Retrieval Program Foundation

This book should represent a guideline for launching an extracorporeal membrane oxygenation (ECMO) program. It describes in detail particularities and special features of planning, setting up, developing, structuring and... read more

ECMO Retrieval Program Foundation

Life Lessons After a Career in Intensive Care Medicine

I have spent the past 30 years working in intensive care medicine. I was drawn to intensive care as a trainee for several reasons. First, I enjoyed the opportunity to care for the sickest patients in the hospital and to use... read more

Improving Access to ECMO for OHCA

Mobile teams using transport accessibility frameworks and principles can significantly improve patient access for out-of-hospital cardiac arrest (OHCA) compared to in-hospital extracorporeal cardiopulmonary resuscitation... read more

Remote Ischemic Conditioning in Septic Shock

The treatment known as RECO did not significantly reduce the severity of organ failure as measured by the mean daily SOFA (sequential organ failure assessment) score from the start of the study to day 4 in patients with septic... read more

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

This analysis of a large randomized trial involving people who are at high risk of experiencing severe outcomes from COVID-19 and who had been vaccinated against SARS-CoV-2 infection found that adding molnupiravir to usual... read more

China: Nearly 250 million people might be infected with COVID-19

According to a leaked government document that has been circulating on social media, it is estimated that up to 248 million people in China may have been infected with COVID-19 since control measures were lifted. This... read more

Heterogeneity in Pediatric ARDS: Challenges and Complexities in Diagnosis and Treatment

Pediatric intensive care physicians are well-acquainted with the concept of heterogeneity, as the patients, pathologies, and treatments they encounter can vary greatly both within the pediatric intensive care unit and within... read more

Family Presence During Cardiac Arrest Resuscitation

This systematic review identified four key findings. Firstly, there was a lack of high-quality evidence on the impact of family presence during resuscitation on patient outcomes. Secondly, family members had varied... read more

Adapting FDA Regulation for AI-Powered Medical Devices

To keep up with the advancement of medical technology, the FDA has been working on a digital health pre-certification program that would allow the agency to pre-approve trusted manufacturers to update their software products.... read more