ECMO During COVID-19 Collaborative Survey
This collaborative survey done by the Society of Thoracic Surgeons/Extracorporeal Life Support Organization highlights several key changes in ECMO utilization and practice in North America: programs performing >20 VV ECMO... read more
Pronation Improves Respiratory Outcomes in Neonates with Respiratory Failure
This study found that 6-hour periods of pronation (lying on the stomach) can improve gas exchange and lung function in neonates (newborn infants) with three types of respiratory failure, without causing any negative effects... read more
Clarifying the Fictions Surrounding Sepsis: Strategies for Improved Management and Outcomes
It is important to clarify the myths surrounding sepsis and to provide a clear understanding of the condition. This can help set realistic expectations about outcomes and inform effective strategies for managing sepsis, including... read more
Time from Infiltrate on Chest Radiograph to VV ECMO in COVID-19 Affects Mortality
Venovenous extracorporeal membrane oxygenation (VV ECMO) has been used to treat severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome; however, patient selection criteria have evolved throughout the... read more
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitated from cardiac arrest did not result in significantly different percentages of patients dying or having severe disability... read more
Bayesian Reanalysis of the Standard vs. Accelerated Initiation of RRT in AKI Trial
Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy (RRT) in Acute Kidney Injury (STARRT-AKI)... read more
Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke
Ischemic strokes in younger adults, those 18 to 50 years old, account for approximately 10% to 15% of all ischemic strokes. Risk factors for stroke between younger and older patients tend to be similar. Younger patients... read more
Making Sense of Lung Function Tests
Respiratory problems are the most common cause of acute admission to hospital. A variety of diagnostic investigations are required, both for acute and clinic assessment. Making Sense of Lung Function Tests, Second Edition... read more
Association Between Oxygen Desaturation Index and Cardiovascular Disease in Non-Sleepy SDB Subtype
In the Chinese community-dwelling population, non-sleepy sleep-disordered breathing (SDB) was highly prevalent. Oxygen desaturation index (ODI), an easily extracted indicator from a type IV sleep monitor, most strongly reflected... read more
Acid-Base Disorders in the Critically III Patient
Acid-base disorders are common in the intensive care unit. By utilizing a systematic approach to their diagnosis, it is easy to identify both simple and mixed disturbances. These disorders are divided into four major categories:... read more
Extracorporeal Membrane Oxygenation for Adults
This new edition presents an evidence-based review of extracorporeal membrane oxygenation (ECMO) for adults, with a particular focus on veno-venous (VV) ECMO. Due to the dramatic impact of COVID-19, the number of institutions... read more
Algorithm to Predict Thromboembolism in COVID-19 Patients
Patients with COVID-19 are at increased risk for thrombosis and might be stratified on admission based on lower Pao2/FiO2 ratio, higher D-dimer levels and history of major hemorrhages. 64 thromboses were recorded in 54... read more
Pros and Cons of Disconnecting the Ventilator During Acute Respiratory Decompensation
Disconnecting the ventilator and manual BMV should be performed in cases where device malfunction is the primary cause of decompensation. These instances are quite rare. Disadvantages of switching to BMV include loss of... read more
Clinical Applications of Magnets on Cardiac Rhythm Management Devices
The growing indications for permanent pacemaker and implantable cardioverter defibrillator (ICD) implantation have increased the number of patients with these cardiac rhythm management devices (CRMDs). Cardiac rhythm... read more
Mechanical Ventilation: For Fun and Benefit
Illustrated and explained simply this book is for anyone that works in an intensive care unit - residents, pulmonary/critical care fellows, therapists, or nurses who wants a better understanding of mechanical ventilation. Easy... read more
The developing kidney: Perinatal aspects and relevance throughout life
Human perinatal nephrology is a very diverse field in medicine, shared—among others—between obstetricians, neonatologists and nephrologists. Extremely low birth weight infants, babies with growth restriction, and specific... read more
Mechanical Ventilation for the ICU Resident: A Concept Based Approach
This book is written primarily with the intent of helping medical residents understand the basics of mechanical ventilation. It is meant to be read during a one-month rotation in the ICU. It is a compilation of concepts... read more
Evaluation of abdominal compression-decompression combined with chest compression CPR performed by a new device
Compression–decompression cardiopulmonary resuscitation (CO-CPR) was more beneficial than standard cardiopulmonary resuscitation (STD-CPR) in terms of survival benefits in patients who have suffered out-of-hospital cardiac... read more
Association of Vancomycin Plus Piperacillin-tazobactam with Early Changes in Creatinine vs. Cystatin C
Although dozens of studies have associated vancomycin + piperacillin–tazobactam with increased acute kidney injury (AKI) risk, it is unclear whether the association represents true injury or a pseudotoxicity characterized... read more
Clinical Application of Mechanical Ventilation
Fundamental concepts of respiratory physiology and the day-to-day duties of a respiratory care professional. Utilizing the wide degree of topics covered, including airway management, understanding ventilator waveforms,... read more
Bougie vs. Endotracheal Tube with Stylet on Successful Intubation
Among critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful intubation on the first attempt compared with use of an endotracheal tube with stylet. Among... read more
Trauma-induced Coagulopathy
Trauma is a major cause of mortality worldwide, and bleeding is the leading preventable cause of death. About one-quarter of patients with severe trauma develop a clotting disorder termed trauma-induced coagulopathy (TIC)... read more
