Emergency and Prophylactic ECMO for Patients Undergoing Valve-in-Valve Transcatheter Aortic Valve Implantation with Small Surgical Bioprosthesis

Mechanical circulatory support (MCS) using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is widely implemented as a rescue device in transcatheter aortic valve implantation (TAVI). Although prophylactic... read more

Device Associated Complications in the ICU

Although mortality in the intensive care unit (ICU) has declined over time, ICU associated complications remain common, affecting up to a half of critically ill patients and resulting in increased mortality, longer hospital... read more

Citrate Anticoagulation for CRRT

Regional citrate anticoagulation (RCA) is a viable option for liver failure patients. The pro-posed inducible metabolic pathway hypothesis challenges the belief in hepatic dominance over citrate metabolism during RCA-CRRT.... read more

Clinical Examination Skills in the Adult Critically Ill Patient

Clinical Examination Skills in the Adult Critically Ill Patient

This well-illustrated book provides detailed guidance on all aspects of physical examination in patients requiring emergency or intensive care. After an introductory section covering basic principles and the recognition of... read more

How to end quiet suffering in the ICU? Identifying and treating hypoactive delirium

The duration of time a person spends in hypoactive delirium predicts higher rates of death, longer length of stay, higher costs of care, and higher rates of acquired dementia in the months and years following critical illness.... read more

Efficacy of β-Blockers in Decreasing Mortality in Sepsis and Septic Shock Patients

This study suggests that the use of β-blockers in sepsis and septic shock patients is associated with a significant decrease in in-hospital mortality and also associated with better patient outcomes. As β-blockers cause... read more

Prehospital Treatment of Severely Burned Patients

In the Berlin metropolitan area, paramedics and emergency physicians caring for severely burned patients need to consider long transport times. Current adherence to prehospital treatment recommendations is unsatisfactory.... read more

Risk Factors for Mortality in Patients with Sepsis or Sepsis-associated Delirium Based on the MIMIC-IV Database

Research on the severity and prognosis of sepsis with or without progressive delirium is relatively insufficient. We constructed a prediction model of the risk factors for 28-day mortality in patients who developed sepsis... read more

Can Clinicians Identify CAP on Ultralow-dose CT?

This study found that clinicians could assess chest ULD-CTs for community-acquired pneumonia (CAP) with high, but not perfect, diagnostic accuracy using an ED radiologist’s assessments as reference standard. Interrater... read more

Withholding Early Parenteral Nutrition on 2-year Mortality in Critically Ill Adults

Late-PN did not alter 2-year survival and physical functioning in adult critically ill patients, independent of anticipated nutritional risk. In this prospective follow-up study of the multicenter EPaNIC randomized controlled... read more

Effectiveness of Fludrocortisone and Hydrocortisone vs. Hydrocortisone Alone in Septic Shock

Steroid use in sepsis is controversial. For example, fludrocortisone–hydrocortisone together may improve survival in septic shock, while hydrocortisone alone may not. A recent subgroup analysis of the APROCCHSS trial... read more

Hospitalizations for Multisystem Inflammatory Syndrome in Children (MIS-C) in US

Multisystem inflammatory syndrome in children (MIS-C) is a rare, serious condition characterized by fever and multiorgan involvement that occurs after SARS-CoV-2 infection. US Centers for Disease Control and Prevention... read more

BPRI and Clinical Outcomes in Patients with Septic Shock

Use of the novel dose-effect index, Blood Pressure Response Index (BPRI) was proposed to allow rapid bedside assessment of the reactivity of septic shock patients to vasoactive drugs, as isolated MAP or VIS cannot reflect... read more

AI to Predicting Mortality Risk in ICU Patients with AKI

To address the limitations of early acute kidney injury (AKI) prediction, researchers have increasingly turned to machine learning methods. However, the success of these models hinges on the selection of relevant features.... read more

Fluid Accumulation Syndrome in Sepsis and Septic Shock

In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more

The Easiest Way to Reduce Antibiotic Resistance Might be Shorter Duration

Antibiotic stewardship garners a lot of attention these days, but we face unique challenges to execute guidelines successfully given that we write more than 13 million antibiotic prescriptions every year in EDs. Variations... read more

The Washington Manual of Critical Care 4th Edition

The Washington Manual of Critical Care 4th Edition

Part of the popular Washington Manual® handbook series, The Washington Manual of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef,... read more