Stories Category: Intensive Care
A Critical Reappraisal of Vasopressin and Steroids in IHCA
In view of the presented discussion/evidence and until publication of new evidence from a large, ongoing Swedish RCT, we suggest that vasopressin-steroids-epinephrine (VSE) might be considered in in-hospital cardiac arrest... read more
Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice
This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside.... read more
Hydrocortisone, Ascorbic Acid, and Thiamine Combination Therapy Efficacy for the Management of Sepsis and Septic Shock
In this systematic review, we found that hydrocortisone, ascorbic acid, and thiamine (HAT) regimen may be useful for reducing the duration of vasopressor use and improve organ functions in patients with sepsis and septic... read more
Patients with TBI: Characteristics, Triage, Primary Referral and Mortality
Traumatic brain injury (TBI) is a potential high-risk condition, but appropriate care pathways, including prehospital triage and primary referral to a specialized neurosurgical centre, can improve neurological outcome and... read more
The role of pleural pressure and airway closure during mechanical ventilation
Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more
Immunosuppression Not Associated with a Higher Incidence of ICU-acquired Bacterial Bloodstream Infections
In this monocentric, retrospective observational cohort study, the incidence of ICU-acquired bacterial BSI was not different between immunocompromised and non-immunocompromised patients. This suggests that the clinical... read more
Sepsis Management in Resource-limited Settings
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More... read more
Improving Outcomes in Nosocomial Pneumonia
Nosocomial pneumonia (NP) represents a leading nosocomial infection and results in substantial morbidity and cost. Over the last several years, the evidence has evolved which directs our approach to NP. Specifically, the... read more
Workbook on Renal Replacement Therapy in ICU (ISCCM)
This workbook focuses on renal replacement therapy in ICU. The incidence of acute kidney injury in critically ill patients is increasing steeply. Acute kidney injury in this setting is associated with high morbidity and mortality.... read more
Two weaning strategies for NIV in COPD patients with ARF
Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more
Incidence of AKI and attributive mortality in ARDS randomized trials
The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and attributable mortality... read more
Sepsis-induced coagulopathy: a matter of timeline
Leone et al. have nicely outlined the most frequent questions about thrombocytopenia in sepsis. Besides thrombocytopenia, sepsis indeed induces numerous pathophysiological changes. Among these, the acute-phase response... read more
Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol
This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more
Oxford Textbook of Advanced Critical Care Echocardiography
Advanced critical care echocardiography brings many benefits to critical care medicine. For those wishing to practice echo at a more advanced level, it is necessary to master the theoretical aspects. The Oxford Textbook... read more
Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease
Procalcitonin level, pneumothorax, neutrophil count at 14 days, and hemoglobin level at 14 days after admission were poor prognostic indicators among patients with NCPD-PJP. Neutrophil count was related with poor prognosis... read more
Proposal for a 4-Level Classification System of Severe COPD Exacerbation According to Healthcare Resource Utilization
The definition of an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) has been modified several times the last decade in Global Initiative for COPD (GOLD) recommendations. According to the updated GOLD... read more
Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO
We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to... read more
