Ten reasons why corticosteroid therapy reduces mortality in severe COVID-19

Ten reasons why corticosteroid therapy reduces mortality in severe COVID-19

Primary outcome in the RECOVERY trial and in the WHO REACT meta-analysis was 28-day mortality. Assessing 28-day mortality may not be the optimal outcome in a trial. Since patients with severe COVID-19 often require prolonged... read more

COVID-19 – In The Eye Of The Storm

COVID-19 – In The Eye Of The Storm

We're back in the eye of the storm, said NHS Chief Executive Sir Simon Stevens. Yes we are. He made no admission of how we got into this storm, nor explained how we’re going to get out of it. His Five Year Plan for the... read more

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

The clinical utilization of extracorporeal membrane oxygenation (ECMO) has seen remarkable expansion since its inception in the early 1970s, including a period of exponential growth in the United States. Venoarterial... read more

The COVID-19 Vaccine: An Expert’s Medical Guide for All

The COVID-19 Vaccine: An Expert’s Medical Guide for All

Vaccine expert Zeil Rosenberg, M.D. shares his medical knowledge, backed by scientific data, about the development, safety and effectiveness of the new COVID-19 vaccines. Dr. Rosenberg M.D. is a Board-Certified Preventive... read more

External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients

External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients

This exploratory analysis provides further evidence that corticosteroid exposure may be associated with increased mortality among septic shock endotype A patients. We previously reported gene expression-based endotypes... read more

A Novel Approach to ICU Survivor Care: A Population Health Quality Improvement Project

A Novel Approach to ICU Survivor Care: A Population Health Quality Improvement Project

Our ICU survivor care process results in decreased mortality and a net annual cost savings to the insurer compared with usual care processes. There was no statistically significant difference in readmission rates. Demographic... read more

COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test

COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test

Urine foaming test (UFT) is useful, particularly in predicting the clinical severity of COVID-19. The UFT could be recommended as a point of care test, rapid and non-invasive method in the diagnosis and follow-up of COVID-19. A... read more

Support and Follow-up Needs of Patients Discharged from ICU After Severe COVID-19

Support and Follow-up Needs of Patients Discharged from ICU After Severe COVID-19

After discharge from an intensive care unit(ICU), over 50% of patients face significant physical, mental and cognitive problems. The COVID-19 pandemic has resulted in a large cohort of these patients who will need follow-up... read more

Nutritional Risk Screening and Body Composition in COVID-19 Patients

Nutritional Risk Screening and Body Composition in COVID-19 Patients

Present findings confirm the clinical utility of NRS-2002 to assess nutritional risk in patients with COVID-19 at hospital admission and in predicting LOS, and that bioimpedance does not seem to add further predictive value.... read more

Gabapentinoids and the Risk of Opioid-Related Adverse Events in Surgical Patients

Gabapentinoids and the Risk of Opioid-Related Adverse Events in Surgical Patients

In this real-world cohort study of patients who underwent major surgery, concomitant use of gabapentinoids with opioids was associated with increased risk of opioid overdose and other opioid-related adverse events; however,... read more

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

This case-control study found evidence to support previously reported associations, discovered new associations between functional seizures and PTSD, anxiety, and depression. An association between cerebrovascular disease... read more

From the Exposome to the Socioexposome in COVID-19 Research

From the Exposome to the Socioexposome in COVID-19 Research

The coronavirus disease 2019 (COVID-19) pandemic continues to expose how access to health care and delivery of care are important concerns, second only to the primary concern regarding exposure to the severe acute respiratory... read more

Medical officials use new tool for COVID patients

Medical officials use new tool for COVID patients

The Barren-Metcalfe County Emergency Medical Service will soon implement a new medical device that will benefit COVID-19 patients as well as emergency medical personnel. The medical device, the Sea-Long helmet, is a clear,... read more

Accuracy of Heparin-Binding Protein in Diagnosing Sepsis

Accuracy of Heparin-Binding Protein in Diagnosing Sepsis

The diagnostic ability of heparin-binding protein is favorable, demonstrating both high sensitivity and specificity in predicting progression to sepsis in critically ill patients. Future studies could assess the incremental... read more

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

A 62-year-old male with a history of hypertension, congestive heart failure, type II diabetes mellitus, and tobacco use presents to the emergency department (ED) with severe left lower leg pain that started six hours ago.... read more

Patient Characteristics Associated With Telemedicine Access During the COVID-19 Pandemic

Patient Characteristics Associated With Telemedicine Access During the COVID-19 Pandemic

In this cohort study of patients scheduled for primary care and medical specialty ambulatory telemedicine visits at a large academic health system during the early phase of the COVID-19 pandemic, older patients, Asian patients,... read more

Extracorporeal Membrane Oxygenation for COVID-19

Extracorporeal Membrane Oxygenation for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed... read more