Tag: AKI
Association Between Osteopontin and Apolipoprotein E gene Polymorphisms and Vancomycin-induced AKI
Individuals carrying specific genotypes of APOE (e2e3) were more prone to develop vancomycin-induced acute kidney injury (AKI), per se. This could apply to other nephrotoxic agents as well. We also observed a significant... read more
Lactate Trajectory Models for Predicting AKI and Mortality in Hyperlactatemia Patients
The present study underscores the significant prognostic value of lactate trajectories in critically ill patients, particularly those with hyperlactatemia. Our findings suggest that rapid lactate clearance is strongly... read more
Clinical Prediction Model Development for Stages of AKI in Critically Ill Patients
Using readily available predictors in the ICU setting, we could develop a prediction model for different stages of AKI with good performance and promising clinical usefulness. Among critically ill patients, acute kidney... read more
Hemoglobin Glycation Index vs. Adverse Outcomes in Critically Ill Patients with Myocardial Infarction
Based on the MIMIC-IV database, this study found that lower HGI is significantly associated with an increased risk of short-, mid- and long-term all-cause mortality in critically ill myocardial infarction (MI) patients. As... read more
Association Between Aspirin and AKI in Critical Patients with Chest Trauma
This analysis of two datasets reveals that aspirin usage is associated with an increased risk of acute kidney injury (AKI) in critical patients with chest trauma; however, no significant association was observed between the... read more
Predicting SA-AKI Mortality Using XGBoost Algorithm
The integration of advanced techniques with the XGBoost algorithm yielded a highly accurate and interpretable model for predicting Sepsis-Associated Acute Kidney Injury (SA-AKI) mortality across diverse populations. It... read more
Clinical Efficacy of Nafamostat Mesylate-assisted CRRT Therapy in SA-AKI Patients
Nafamostat Mesylate (NM)-assisted continuous renal replacement therapy (CRRT) therapy significantly improves the therapeutic efficacy of patients with sepsis-associated acute kidney injury (SA-AKI). This combined approach... read more
Pre-ICU Statin Use, AKI and in Hospital Mortality in Sepsis Patients
Pre-ICU statin therapy is associated with a lower risk of acute kidney injury (AKI), and improved in-hospital survival among obese patients with sepsis, suggesting its potential role as a protective measure in this high-risk... read more
Diastolic Dysfunction Increases AKI Rick in COVID-19 Patients
Diastolic dysfunction increases the risk of acute kidney injury (AKI) in patients with severe COVID-19. Using point-of-care ultrasound (PoCUS) to assess left ventricular diastolic function in the ICU may be a useful parameter... read more
Dynamic Nomogram for AKI Prediction in ICU Patients with AHF
After strict screening, 1338 patients with acute heart failure (AHF) were included in the derivation set, and 3,129 in the validation set. Sepsis, use of human albumin, age, mechanical ventilation, aminoglycoside administration,... read more
Association Between the Lactate-to-Albumin Ratio (LAR) Index and AKI Risk in Critically Ill Patients with Sepsis
Lactate-to-albumin ratio (LAR) is an emergency predictive indicator of sepsis-related mortality. An elevated LAR is associated with poor outcomes in critically ill patients. However, its predictive value for acute kidney... read more
AKI and Mortality Predictors of Systemic Autoimmune Diseases and COVID-19
The present study highlights renal parameters and outcomes associated with various systemic autoimmune diseases and COVID-19. Patients who presented with low oxygen saturation (... read more
Zosyn vs. Efepime: Which One Is Safer?
While both piperacillin-tazobactam and cefepime are commonly used to treat infections caused by Pseudomonas aeruginosa in hospitalized patients, there is a concern that piperacillin-tazobactam may lead to acute kidney injury... read more
Severe Sepsis-associated AKI and Outcomes
These results demonstrate an association between an index episode involving SA-AKI and the composite outcome in a defined population. Identification of this group may allow intensive nephrology follow-up and secondary... read more
Clinical Outcomes of Early Phenotype-Desirable Antimicrobial Therapy for Enterobacterales Bacteremia
This is first study to compare clinical outcomes between patients with E coli, K pneumoniae, K oxytoca, and P mirabilis BSIs receiving early PDAT vs delayed PDAT using DOOR analysis. Receiving early phenotype-desirable... read more
Prediction of AKI in ICU Patients Based on Interpretable Machine Learning
The machine learning model described in this study is capable of accurately predicting the onset of AKI in ICU patients up to 24 hours in advance. Validated within the MIMIC-IV and MIMIC-III databases, the model demonstrates... read more
Textbook of Cardiorenal Medicine
This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings... read more
Fluid Bolus Therapy with 20% Albumin vs. Crystalloid-based Regimen
In this trial involving adult patients undergoing cardiac surgery with cardiopulmonary bypass, 20% albumin fluid bolus therapy (FBT) compared to crystalloid FBT did not decrease the occurrence of acute kidney injury (AKI).... read more
New Insights on CRRT for ARDS
In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more
Increased Lactate Dehydrogenase to Albumin Ratio Associated with Short-term Mortality in Septic ICU Patients
Elevated lactate dehydrogenase to albumin ratio (LAR) was found to be significantly associated with an increased risk of all-cause mortality at 28 and 90 days in septic patients. LAR was suggested to be promising biomarker... read more
Rethinking Energy and Protein Provision for Critically Ill Patients
In critically ill patients, we suggest that energy and protein be delivered progressively in stable or recovering patients. If a patient deteriorates, regardless of days spent in the ICU, low-dose energy and protein should... read more
Clinical Companion in Nephrology
The second edition of this educational book provides an updated resource on how best to discuss and manage acute and chronic presentations of renal diseases. All chapters have been reviewed and updated to reflect changes... read more
