Double Mortality Risk for Depressed Heart Disease Patients

Double Mortality Risk for Depressed Heart Disease Patients

Among 24,000 patients with heart disease studied over many years, those who suffered from depression were at twice the risk of dying, according recently published findings from Intermountain Healthcare. A statistical analysis... read more

Ventilation Rate During Adult CPR with Tracheal Tube

Ventilation Rate During Adult CPR with Tracheal Tube

The optimal ventilation rate during cardiopulmonary resuscitation (CPR) with a tracheal tube is unknown. A new systematic review finds that a ventilation rate recommendation of 10 min-1 during adult CPR with a secure airway... read more

Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock

Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock

Several studies have reported a survival benefit for polymyxin B hemoperfusion treatment in patients with severe sepsis and septic shock. However, recently, a propensity-matched analysis and a randomized controlled trial... read more

Effectiveness and Safety of Magnesium Replacement in Critically Ill Patients Admitted to the ICU

Effectiveness and Safety of Magnesium Replacement in Critically Ill Patients Admitted to the ICU

Rules of thumb for the replacement of electrolytes, including magnesium, in critical care settings are used, despite minimal empirical validation of their ability to achieve a target serum concentration. This study's... read more

Should All Massively Transfused Patients Be Treated Equally?

Should All Massively Transfused Patients Be Treated Equally?

Although balanced resuscitation has become integrated into massive transfusion practice, there is a paucity of evidence supporting the delivery of high ratios of plasma and platelet to RBCs in the nontrauma setting. This... read more

Frequency of Exacerbations in Patients with COPD

Frequency of Exacerbations in Patients with COPD

Present treatment strategies to stratify exacerbation risk in patients with chronic obstructive pulmonary disease (COPD) rely on a history of two or more events in the previous year. We aimed to understand year to year variability... read more

Intubation During CPR was Associated with Worse Survival and Brain Health

Intubation During CPR was Associated with Worse Survival and Brain Health

Intubating patients in cardiac arrest is widely considered ideal care. But in this analysis, the patients who were intubated were less likely to survive (16% vs 19%) or have a good functional outcome (~11% vs ~14%). Intubation... read more

I’m your Anesthesiologist. Let me explain what that means

I’m your Anesthesiologist. Let me explain what that means

Anesthesiologists are the guardian angels of the operating room. Their primary purpose is to keep you alive so you can undergo whatever procedure you need. While we may only meet you shortly before we take you to the operating... read more

A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease

A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease

ILD is a serious complication in RA, with a significantly increased mortality compared with a large matched cohort of RA comparisons without ILD. Mortality risks were assessed using Kaplan-Meier mortality curves, and hazard... read more

Sepsis-Associated 30-Day Risk-Standardized Readmissions

Sepsis-Associated 30-Day Risk-Standardized Readmissions

One third of sepsis survivors were readmitted and wide variation exists between hospitals. Several demographic and structural factors are associated with this variation. Measures of higher quality in-hospital care were correlated... read more

Analysis of Unplanned Postoperative Admissions to the ICU

Analysis of Unplanned Postoperative Admissions to the ICU

Our study is the first diverse analysis of unplanned postoperative ICU admissions in the literature across multiple specialties and practice models. We found an association of advanced age, higher ASA PS class, and duration... read more

Muscle Mass and Physical Recovery in ICU: Innovations for targeting of Nutrition and Exercise

Muscle Mass and Physical Recovery in ICU: Innovations for targeting of Nutrition and Exercise

New innovative techniques are demonstrating promise to target recovery from PICS utilizing a combination of objective LBM and metabolic assessment, targeted nutrition interventions, personalized exercise interventions for... read more

Cardiovascular Testing and Clinical Outcomes in Emergency Department Patients With Chest Pain

Cardiovascular Testing and Clinical Outcomes in Emergency Department Patients With Chest Pain

In patients who present to the emergency department with chest pain without evidence of ischemia, is cardiac testing - noninvasive testing or coronary angiography - associated with changes in revascularization or acute myocardial... read more

Boarding ICU patients: Are our rounding practices subpar?

Boarding ICU patients: Are our rounding practices subpar?

Surgical Intensive Care Unit (SICU) patients "boarding" in ICUs other than the designated home unit have been shown to suffer increased rates of complications. We hypothesized that ICU rounding practices are different... read more

Extracorporeal membrane oxygenation for poisoning in adult patients: outcomes and predictors of mortality

Extracorporeal membrane oxygenation for poisoning in adult patients: outcomes and predictors of mortality

Data on outcomes from severe poisoning in adults receiving extracorporeal membrane oxygenation (ECMO) is currently confined to single-center experiences or specific etiologies. While ECMO cannot facilitate toxin removal,... read more

Data Sharing Statements for Clinical Trials

Data Sharing Statements for Clinical Trials

The International Committee of Medical Journal Editors (ICMJE) believes there is an ethical obligation to responsibly share data generated by interventional clinical trials because trial participants have put themselves at... read more

Critical care at the end of life: a population-level cohort study of cost and outcomes

Critical care at the end of life: a population-level cohort study of cost and outcomes

Despite the high cost associated with ICU use at the end of life, very little is known at a population level about the characteristics of users and their end of life experience. In this study, our goal was to characterize... read more