72‐h Infusion of Prostacyclin in Mechanically Ventilated Patients with Pulmonary Infection and Endotheliopathy

Acute respiratory failure (ARF) is common in critically ill patients, and 50% of patients in intensive care units require mechanical ventilation. The COVID‐19 pandemic revealed that COVID‐19 infection induced ARF... read more

ARF Caused by Penicillium Marneffei Infection After Kidney Transplantation

Penicillium Marneffei (PM) infections often present with nonspecific clinical manifestations, and severe respiratory failure (ARF) after infection is particularly uncommon. This case report a patient who developed severe... read more

Extended Prone Position and 90-Day Mortality in Mechanically Ventilated Patients with COVID-19

Extended prone positioning (PP) was associated with improved 90-d survival in subjects with COVID-19 undergoing mechanical ventilation for severe ARDS. These findings suggest the potential benefit of EPP in the management... read more

Impact of the Timing of Invasive Mechanical Ventilation in Sepsis Patients

In patients with sepsis admitted to ICU and received invasive mechanical ventilation (MV), early MV was associated with lower ICU and in-hospital mortality and a shorter ICU stay. Additionally, at ICU discharge, early... read more

Oxygen Therapy in Acute Hypoxemic Respiratory Failure

Although largely used, the place of oxygen therapy and its devices in patients with acute hypoxemic respiratory failure (ARF) deserves to be clarified. The French Intensive Care Society (Société de Réanimation de Langue... read more

Predictors of High-flow Nasal Cannula Failure in COVID-19 Patients

A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of high-flow nasal cannula... read more

BPRI and Clinical Outcomes in Patients with Septic Shock

Use of the novel dose-effect index, Blood Pressure Response Index (BPRI) was proposed to allow rapid bedside assessment of the reactivity of septic shock patients to vasoactive drugs, as isolated MAP or VIS cannot reflect... read more

High-flow Nasal Cannula Oxygen vs. NIV in AHF-related ARF

In this pilot study, we did not observe a statistically significant difference in changes in respiratory rate among patients with acute respiratory failure (ARF) due to acute heart failure (AHF) and managed with high-flow... read more

Two weaning strategies for NIV in COPD patients with ARF

Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more

Two weaning strategies for NIV in COPD patients with ARF

Lung Ultrasound in the Critically Ill: The BLUE Protocol

Written by a pioneer in critical care ultrasound, this book discusses the basic technique and "signatures" of lung ultrasound and explains its main clinical applications. The tools and clinical uses of the BLUE protocol,... read more

Lung Ultrasound in the Critically Ill: The BLUE Protocol

HFNO Alone or Alternating with NIV in ARF Patients

In critically ill immunocompromised patients with acute respiratory failure (ARF), the mortality rate did not differ between HFNO alone and non-invasive ventilation (NIV) alternating with high-flow nasal oxygen (HFNO). However,... read more

HFNO Alone or Alternating with NIV in ARF Patients

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

Renal Failure and Replacement Therapies

Increased recognition of the overlap between critical care and renal medicine, and recent advances in the understanding of acute renal failure (ARF) and the application of renal replacement therapies (RRTs), have brought... read more

Renal Failure and Replacement Therapies

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January... read more

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

Dynamic and Hybrid Configurations for ECMO

Dynamic or hybrid configurations for extracorporeal membrane oxygenation (ECMO) are needed when patient physiology or clinical conditions change. Dynamic configurations included configurations converting from veno-arterial... read more

Dynamic and Hybrid Configurations for ECMO