Tag: ARF
Prolonged acute and post-acute care recovery of physical function in survivors of acute respiratory failure
The proportion of survivors of acute respiratory failure is growing; yet, many do not regain full function and require prolonged admission in an acute or post-acute care facility. Patients who require prolonged admission... read more
Effects of High-Flow Nasal Cannula on the Work of Breathing in Patients Recovering From ARF
High-flow nasal cannula, when set at 60 L/min, significantly reduces the indexes of respiratory effort in adult patients recovering from acute respiratory failure (ARF). This effect is associated with an improvement in... read more
Prospective Assessment of the Feasibility of a Trial of Low Tidal Volume Ventilation for Patients with Acute Respiratory Failure
Use of initial tidal volumes less than 8 ml/kg PBW is common at hospitals participating in the NHLBI PETAL Network. After considering the size and budgetary requirement for a cluster-randomized trial of LTVV vs. usual care... read more
Remodeling ICU Care
A new study finding that two antipsychotics were no more effective than placebo for delirium in critical illness spurs discussion about alternative methods for managing that care. Neither haloperidol nor ziprasidone — both... read more
Carbonic anhydrase inhibitors in patients with respiratory failure and metabolic alkalosis
In patients with respiratory failure and metabolic alkalosis, carbonic anhydrase inhibitor therapy may have favorable effects on blood gas parameters. In mechanically ventilated patients, carbonic anhydrase inhibitor therapy... read more
Sedation and Mobilization during Venovenous Extracorporeal Membrane Oxygenation for ARF
The majority of respondents reported targeting moderate to deep sedation following cannulation, with the use of sedative and opioid infusions. There is considerable variability surrounding early physical therapy and mobilization... read more
Antipsychotic Prescribing Patterns During and After Critical Illness
In this study, antipsychotics were used to treat nearly half of all antipsychotic-naïve ICU patients and were prescribed at discharge to 24% of antipsychotic-treated patients. Treatment with an atypical antipsychotic greatly... read more
Noninvasive Ventilation in Patients With ARF and Do-Not-Intubate and Comfort-Measures-Only Orders
A large proportion of patients with do-not-intubate orders who received noninvasive ventilation survived to hospital discharge and at 1 year, with limited data showing no decrease in quality of life in survivors. Provision... read more
Medications and RRT: We Know How to Dose, Right?
Dr. Fraser, MD, speaks with Bruce A. Mueller, PharmD, FCCP, FASN, about his talk presented at the 47th Critical Care Congress in San Antonio, Texas, entitled "Artificial Kidney Meets Mechanical Lung: Comanaging the Patient... read more
Should We Manage All Septic Patients Based on a Single Definition?
It is indisputable from the biological and clinical perspectives that not all cases of sepsis are the same. On the contrary, most have great many differences, that is, different portals of entry, clinical manifestations,... read more
Delayed Intubation Linked to Poor Outcome
The optimal timing of endotracheal intubation in critically ill patients requiring invasive mechanical ventilation remains undefined. A new analysis of the large, prospective Intensive Care Over Nations (ICON) database compares... read more
Choosing the Appropriate Configuration and Cannulation Strategies for ECMO
Extracorporeal membrane oxygenation (ECMO) is becoming a common procedure to support patients with severe cardio-circulatory or respiratory failure as well as in case of combined compromise of the two systems. Deciding which... read more
Acute Hypoxemic Respiratory Failure in Immunocompromised Patients
In immunocompromised patients with acute hypoxemic respiratory failure (ARF), initial management aims primarily to avoid invasive mechanical ventilation (IMV). HFNC has an effect on intubation but not on mortality rates.... read more
Initial Nutritional Management During NIV and Outcomes
Patients starting noninvasive ventilation (NIV) to treat acute respiratory failure are often unable to eat and therefore remain in the fasting state or receive nutritional support. Nearly three-fifths of patients receiving... read more
Perspectives of Survivors, Families and Researchers on Key Outcomes for Research in ARF
There is heterogeneity among the outcomes evaluated in studies of survivors of acute respiratory failure (ARF). Patient, family and researcher groups supported inclusion of outcome domains that fit within the PICS framework.... read more
Core Outcome Measures for Clinical Research in ARF Survivors
This Core Outcome Measurement Set is recommended for use in all clinical research evaluating acute respiratory failure (ARF) survivors after hospital discharge. In the future, researchers should evaluate measures for outcomes... read more
Focus on Ventilation and Airway Management in the ICU
Airway and ventilation management are particularly challenging in the intensive care unit (ICU), and are associated with high morbidity and mortality. Figure summarizes some of the more recent findings from the literature.... read more
Potentially modifiable factors contributing to sepsis-associated encephalopathy
Acute renal failure and common metabolic disturbances represent potentially modifiable factors contributing to sepsis-associated encephalopathy. However, a true causal relationship has yet to be demonstrated. Our study confirms... read more
Improving Long-Term Outcomes Research for ARF
Alison Turnbull, DVM, MPH, PhD discusses the heterogeneity in outcome measures in our field and the need for a Core Outcome Measurement Set (COMS) to standardize reporting of important outcomes. As part of the consensus process,... read more
Hemolytic Uremic Syndrome (HUS): Pearls and Pitfalls
A three-year-old male presents with mom for seven days of fever, diarrhea, and decreased activity. When you walk into the room, you note a listless-appearing boy with pallor. His eyes appear sunken. He is tachycardic, tachypneic,... read more
Critical care ultrasonography in acute respiratory failure
CCUS combining CCE and chest ultrasonography rapidly provides valuable information in patients presenting with ARF. A pragmatic and systematic applied protocol may first evaluate how aerated is the lung and whether there... read more
