The Washington Manual of Critical Care 4th Edition

The Washington Manual of Critical Care 4th Edition

Part of the popular Washington Manual® handbook series, The Washington Manual of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef,... read more

Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease

Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease

Procalcitonin level, pneumothorax, neutrophil count at 14 days, and hemoglobin level at 14 days after admission were poor prognostic indicators among patients with NCPD-PJP. Neutrophil count was related with poor prognosis... read more

Ineffective Airway Clearance Nursing Diagnosis & Care Plans

Ineffective Airway Clearance Nursing Diagnosis & Care Plans

Ineffective airway clearance is the inability to clear secretions or obstructions from the respiratory tract. This can be detrimental to breathing and create complications. Secretions can be problematic as a result of... read more

Chronic Obstructive Pulmonary Disease, An Issue of Clinics in Chest Medicine

Chronic Obstructive Pulmonary Disease, An Issue of Clinics in Chest Medicine

This issue of Clinics in Chest Medicine, guest-edited by Dr. Gerard Criner and Dr. Bartolome Celli, is focused on Chronic Obstructive Pulmonary Disease. Topics discussed in this issue include but are not limited to: COPD... read more

Sotrovimab Effect Among High-risk COVID-19 Patients

Sotrovimab Effect Among High-risk COVID-19 Patients

Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more

Inhaled Corticosteroid Use on COVID-19 Outcomes Among Hospitalized Adult Asthmatics

Inhaled Corticosteroid Use on COVID-19 Outcomes Among Hospitalized Adult Asthmatics

While our findings confirm trends observed by others with respect to risk factors among asthmatics with COVID-19, differences based on sex, ethnicity and ICS use in asthmatics were observed. Our finding that ICS use was associated... read more

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

During the COVID-19 pandemic, despite early concerns the impact oral corticosteroids might have on the effects of acute COVID-19 reported by the WHO and the potential severity of disease in patients with asthma and chronic... read more

UK 28-Day Mortality Trends of COVID-19 Patients

UK 28-Day Mortality Trends of COVID-19 Patients

There was a marked deterioration in outcomes for patients admitted to critical care at the peak of the second wave of coronavirus disease 2019 in United Kingdom (December 2020–January 2021), compared with the post-first-wave... read more

The Relationship Between Vitamin D and Asthma Exacerbation

The Relationship Between Vitamin D and Asthma Exacerbation

Asthma is a chronic airway inflammatory condition that affects millions of people worldwide. It presents with reversible bronchoconstriction that makes it difficult for patients to breathe. Asthma flare-ups have several triggers,... read more

Adrenal Insufficiency in Patients Taking Benralizumab as Corticosteroid Sparing Therapy

Adrenal Insufficiency in Patients Taking Benralizumab as Corticosteroid Sparing Therapy

A personalised regimen of tapering oral corticosteroids in the presence of the anti-IL5 receptor α-directed cytolytic monoclonal antibody benralizumab can help to achieve elimination or dose reduction of oral corticosteroids... read more

Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations

Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations

In uncontrolled, moderate-to-severe asthma, higher baseline FeNO levels were associated with greater risk of severe asthma exacerbations, particularly in combination with elevated eosinophil count and prior exacerbations,... read more

Steer Clear of Magnesium for COPD

Steer Clear of Magnesium for COPD

Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more

Will the asthma revolution fostered by biologics also benefit adult ICU patients?

Will the asthma revolution fostered by biologics also benefit adult ICU patients?

Asthma exacerbations are inflammatory events that rarely result in full hospitalization following an ER visit. Unfortunately, certain patients require prolonged support, including occasional external lung support through... read more

Asthma Among Hospitalized Patients with COVID-19 and Related Outcomes

Asthma Among Hospitalized Patients with COVID-19 and Related Outcomes

Among hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities. Future population-based studies... read more

ICU Survivors Have a Substantial Higher Risk of Developing New Chronic Conditions Compared to a Population-Based Control Group

ICU Survivors Have a Substantial Higher Risk of Developing New Chronic Conditions Compared to a Population-Based Control Group

ICU patients have more chronic conditions during the year before ICU admission compared with a population-based control group and a five times higher odds on developing one or more new chronic conditions compared with the... read more

Association of Antibiotic Treatment with Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated with Systemic Corticosteroids

Association of Antibiotic Treatment with Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated with Systemic Corticosteroids

Antibiotic therapy may be associated with a longer hospital length of stay, higher hospital cost, and similar risk of treatment failure. These results highlight the need to reduce inappropriate antibiotic prescribing among... read more

Effect of Azithromycin on Asthma Exacerbations and Quality of Life in Adults with Persistent Uncontrolled Asthma

Effect of Azithromycin on Asthma Exacerbations and Quality of Life in Adults with Persistent Uncontrolled Asthma

Adults with persistent symptomatic asthma experience fewer asthma exacerbations and improved quality of life when treated with oral azithromycin for 48 weeks. Azithromycin might be a useful add-on therapy in persistent asthma.... read more