Uncommon Diseases in the ICU

This book highlights the practical characteristics of uncommon diseases and presents the most relevant features for the management of intensive care units. It does not aim to provide an exhaustive description of uncommon... read more

Uncommon Diseases in the ICU

Long COVID Associated with Reduced Circulating Serotonin Levels

Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been formulated... read more

Long COVID Associated with Reduced Circulating Serotonin Levels

COVID-19-associated Sepsis: Incidence and Mortality

In this retrospective cohort study of hospitalized adults, SARS-CoV-2 accounted for approximately 1 in 6 cases of sepsis during the first 33 months of the COVID-19 pandemic. In-hospital mortality rates for SARS-CoV-2–associated... read more

COVID-19-associated Sepsis: Incidence and Mortality

Estimating Seroprevalence of COVID-19 Infection After Omicron Outbreak

This study aimed to investigate the seroprevalence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibodies among individuals aged 18 years and older. Population-based study was conducted within the Arizona... read more

Estimating Seroprevalence of COVID-19 Infection After Omicron Outbreak

Ferroptosis and Pyroptosis Signatures in Critical COVID-19 Patients

Critical COVID-19 patients admitted to the intensive care unit (ICU) frequently suffer from severe multiple organ dysfunction with underlying widespread cell death. Ferroptosis and pyroptosis are two detrimental forms... read more

Ferroptosis and Pyroptosis Signatures in Critical COVID-19 Patients

COVID-19 Critical and Intensive Care Medicine Essentials

This book provides healthcare professionals in Critical Care setting an easy consultation guide to fight against COVID-19. The book is divided into sections: Fundamentals of COVID-19, Pneumological critical care, Neurological... read more

COVID-19 Critical and Intensive Care Medicine Essentials

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

The study revealed that the utilization of non-ICU sophisticated ventilators was linked to a higher mortality rate when compared to standard ICU ventilators in COVID-19 patients with ARDS. However, given the shortage and... read more

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

Elevation of D-dimer Levels Associated with Early Need for Mechanical Ventilation Support in COVID-19 Patients

Hypoxia and thrombosis are hallmarks of severe COVID-19, and each of them can exaggerate the other, adding to the magnitude of the disease. Our study proposes that D-dimer, commonly used as a marker of thrombosis, can also... read more

Elevation of D-dimer Levels Associated with Early Need for Mechanical Ventilation Support in COVID-19 Patients

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

During the COVID-19 pandemic, healthcare delivery was affected in various ways. For example, acute and chronic cardiovascular diseases (CVDs) and events were less frequently observed in hospitals, both because public health... read more

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Remdesivir, an antiviral medication, may benefit patients who are infected with mild or moderate forms of COVID-19 infection. Several research findings have suggested the safety and efficacy of remdesivir for a five- to 10-day... read more

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Manual of Cardiac Intensive Care

Addressing the changing needs of clinicians in today’s CCU, ICU and CICU, Manual of Cardiac Intensive Care is an easy-to-use, point-of-care reference for cardiologists, intensivists, physicians, trainees, and other health... read more

Manual of Cardiac Intensive Care

Every Deep-Drawn Breath: A Critical Care Doctor on Healing, Recovery, and Transforming Medicine in the ICU

A world-renowned critical care doctor offers hope for ICU patients and their families in this timely, urgent, and compassionate narrative. Over the next ten years, 40 to 60 million people in this country will be admitted... read more

Every Deep-Drawn Breath: A Critical Care Doctor on Healing, Recovery, and Transforming Medicine in the ICU

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Science is digging for the varied presentation of COVID-19 patients exposed to the same risk factors, and medical conditions may be influenced by the presence of polymorphic genetic variants. This study investigated the link... read more

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Balloon therapy is an empirical example that patients with respiratory tract diseases can use to improve their daily care. The diaphragm and ribs are expanded and raised by the intercostal muscles, which are activated during... read more

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Oxygen Support Needs in Children with RSV vs. COVID-19

Children with respiratory syncytial virus (RSV) had a higher risk of pneumonia, bronchiolitis, and a hospital stay of more than 4 days vs children with COVID-19 or influenza. Investigators compared demographic and clinical... read more

Oxygen Support Needs in Children with RSV vs. COVID-19

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

Unmodified risk variables for nosocomial bloodstream infections (BSIs) included male sex and leukocytosis at admission. Using methylprednisolone and obtaining a cumulative dosage of dexamethasone were adjusted risk variables... read more

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

The Song of the Cell: An Exploration of Medicine and the New Human

In the late 1600s, Mukherjee sets the stage for an extraordinary tale. It revolves around two notable individuals: Robert Hooke, a renowned English polymath, and Antonie van Leeuwenhoek, an eccentric Dutch cloth-merchant.... read more

The Song of the Cell: An Exploration of Medicine and the New Human

Why We Can Thank a Polio Emergency for the Birth of Intensive Care

An outbreak of polio in 1950s Denmark led one hospital to pioneer mechanical ventilation, constant monitoring of vital signs and other innovations that are saving lives to this day. The COVID-19 pandemic has brought home... read more

Why We Can Thank a Polio Emergency for the Birth of Intensive Care

Increased Fungal Infections Hospitalizations during COVID-19

An examination of a large healthcare database in the United States revealed a significant rise in hospitalization rates related to fungal infections between 2019 and 2021. This increase was primarily driven by hospitalizations... read more

Increased Fungal Infections Hospitalizations during COVID-19

Disseminated Intravascular Coagulation in COVID-19 Setting

Disseminated intravascular coagulation (DIC) is an acquired syndrome that can lead to catastrophic thrombosis and hemorrhage. In DIC, an uncontrolled release of pro-inflammatory mediators activates tissue factor-dependent... read more

Disseminated Intravascular Coagulation in COVID-19 Setting

Secondary Bacterial Pneumonia is the Key Factor in COVID-19 Fatalities Not Cytokine Storm

A recent study found that secondary bacterial pneumonia, rather than the much-discussed “cytokine storm,” is a significant factor in COVID-19-related fatalities. Almost half of the patients who required mechanical... read more

Secondary Bacterial Pneumonia is the Key Factor in COVID-19 Fatalities Not Cytokine Storm