Tag: cytokine
Impaired peripheral mononuclear cell metabolism in patients at risk of developing sepsis
Dysregulated immune response is a key driver of disease progression in sepsis and known to be associated with impaired cellular metabolism. This association has been studied mostly in the late stage sepsis patients. Here,... read more
Longitudinal Analyses Reveal Immunological Misfiring in Severe COVID-19
Recent studies have provided insights into the pathogenesis of COVID-19. Yet, longitudinal immunological correlates of disease outcome remain unclear. Here, we serially analysed immune responses in 113 COVID-19 patients with... read more
Corticosteroids for Critically Ill COVID-19 Patients with Cytokine Release Syndrome
Approximately 5% of coronavirus disease (COVID-19) patients will require admission to an intensive care unit (ICU). Among these patients, the most severe cases may be mediated by a late-onset systemic inflammatory response... read more
The Protective Effects of Regional Hypothermia on Injured Limbs Combined with Hemorrhagic-shock & Tourniquet
The aim of this study is to investigate the protective effects of regional hypothermia (RH) on rabbits' limbs injured by a steel-ball combined with hemorrhagic-shock, and then employed tourniquet over-time, tried to identify... read more
New Cytokine Approach is Synergistic With Checkpoint Inhibitors
Among the new agents currently being explored in clinical trials, NKTR-214 stands out as a new cytokine therapy approach that could show additive benefit when combined with checkpoint inhibitors. ... read more
