Idiopathic Intracranial Hypertension

A 22 year-old female with a medical history of migraines and obesity who presents to the Emergency Department with a headache. Her headache was gradual in onset, but has progressively worsened and has not been relieved... read more

Idiopathic Intracranial Hypertension

Primary Management of Polytrauma

This well-illustrated book describes a practical approach to the primary management of patients who have multiple injuries, or polytrauma, with the aim of providing medical and paramedical personnel with the knowledge required... read more

Primary Management of Polytrauma

Diagnosis of Nonventilated Hospital-acquired Pneumonia

Nonventilated hospital-acquired pneumonia (NV-HAP) poses several barriers for diagnosis compared with VAP, and the available knowledge is limited. A call for further research in diagnosis of nonventilated HAP is urgent.... read more

Diagnosis of Nonventilated Hospital-acquired Pneumonia

Neonatal Early-Onset Sepsis Evaluation

Twelve years ago, we began a National Institutes of Health–funded study of neonatal early-onset sepsis (EOS) whose goal was to develop multivariate predictive models that could be used by clinicians to evaluate a newborn’s... read more

Neonatal Early-Onset Sepsis Evaluation

Hydration for Infants with Bronchiolitis

Bronchiolitis is the most common lower respiratory tract infection in infants and the leading cause of hospital admission. Hydration is a mainstay of treatment, but insufficient evidence exists to guide clinical practice.... read more

Hydration for Infants with Bronchiolitis

Biomarker Profiles of Coagulopathy and Alveolar Epithelial Injury in ARDS

Coagulopathy and alveolar epithelial injury were observed in both patients with direct common risk factors (dARDS) and with idiopathic or immune-related diseases (iARDS). However, their biomarker profiles were significantly... read more

Biomarker Profiles of Coagulopathy and Alveolar Epithelial Injury in ARDS

What should we stop doing in the ICU?

Intensive care is an interesting specialty. From all the early excitement in the 1970s, passing through two decades of intensive physiological use at the bedside, intensive care landed on the rough ground of modern randomized... read more

Abdominal Compartment Syndrome

Abdominal compartment syndrome (ACS) is defined by sustained intra-abdominal pressure (IAP) > 20 mm Hg with associated organ injury. The condition was first described in 1863, but not significantly discussed until the 1990s.... read more

Abdominal Compartment Syndrome

Clustering Algorithms Usage in Critical Care Research Unravel Patient Heterogeneity

Critically ill patients constitute the most heterogeneous population in the hospital, with the highest rates of acute and chronic multi-morbidity. Daily, two critically ill patients are admitted to the ICU with the same... read more

Clustering Algorithms Usage in Critical Care Research Unravel Patient Heterogeneity

The Hospitalist Role in Treating Opioid Use Disorder

Opioid use disorder, like many of the other conditions we see, is a chronic relapsing remitting medical disease and a risk factor for premature mortality. When a patient with diabetes is admitted with cellulitis, we might... read more

The Hospitalist Role in Treating Opioid Use Disorder

Manual of Traumatic Brain Injury: Assessment and Management

Now completely revised and updated, Manual of Traumatic Brain Injury: Assessment and Management, Second Edition is a comprehensive evidence-based guide to brain injury diagnosis, treatment, and recovery, delivered in a succinct... read more

Manual of Traumatic Brain Injury: Assessment and Management

Perioperative Kidney Injury: Principles of Risk Assessment, Diagnosis and Treatment

The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction... read more

Perioperative Kidney Injury: Principles of Risk Assessment, Diagnosis and Treatment

Antibiotics for Sepsis

Antibiotics for Sepsis - Does Each Hour Really Count? Or is it Incestuous Amplification? - by Prof Mervyn Singer "Each hour's delay in initiating antibiotics costs lives" is a doctrine that has attained quasi religious status.... read more

Antibiotics for Sepsis

Early Prediction of Prognosis in Elderly Acute Stroke Patients

Acute stroke has a high morbidity and mortality in elderly population. Baseline confounding illnesses, initial clinical examination, and basic laboratory tests may impact prognostics. In this study, we aimed to establish... read more

Early Prediction of Prognosis in Elderly Acute Stroke Patients

In-hospital Mortality Associated with the Misdiagnosis or Unidentified Site of Infection at Admission

Rapid detection, early resuscitation, and appropriate antibiotic use are crucial for sepsis care. Accurate identification of the site of infection may facilitate a timely provision of appropriate care. We aimed to investigate... read more

In-hospital Mortality Associated with the Misdiagnosis or Unidentified Site of Infection at Admission

Unaccountable: What Hospitals Won’t Tell You and How Transparency Can Revolutionize Health Care

Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's bestseller The Checklist Manifesto. A Johns Hopkins surgeon and professor of public health, he can testify to the amazing power of modern... read more

Unaccountable: What Hospitals Won’t Tell You and How Transparency Can Revolutionize Health Care

Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and... read more

Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again

Prognostic Accuracy of the Serum Lactate Level, the SOFA Score and the qSOFA Score for Mortality Among Adults with Sepsis

Sepsis is a common critical condition caused by the body’s overwhelming response to certain infective agents. Many biomarkers, including the serum lactate level, have been used for sepsis diagnosis and guiding treatment.... read more

Prognostic Accuracy of the Serum Lactate Level, the SOFA Score and the qSOFA Score for Mortality Among Adults with Sepsis