Improving Patient Outcomes: Sepsis Protocols and Rapid Host Response Technologies

Patients come into the emergency department (ED) with symptoms, not diagnoses. That’s when time is of the essence. Clinicians must quickly triage patients and establish an appropriate care pathway to obtain the best possible... read more

Army Scientists’ Technique for Early Sepsis Detection in Burn Patients Submitted to FDA

A new invention developed at the U.S. Army Medical Research and Development Command uses an artificial intelligence machine learning algorithm to identify whether burn patients are at risk of experiencing life-threatening... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Core Concepts in Acute Kidney Injury

This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis... read more

Core Concepts in Acute Kidney Injury

Can Clinicians Identify CAP on Ultralow-dose CT?

This study found that clinicians could assess chest ULD-CTs for community-acquired pneumonia (CAP) with high, but not perfect, diagnostic accuracy using an ED radiologist’s assessments as reference standard. Interrater... read more

Hospitalizations for Multisystem Inflammatory Syndrome in Children (MIS-C) in US

Multisystem inflammatory syndrome in children (MIS-C) is a rare, serious condition characterized by fever and multiorgan involvement that occurs after SARS-CoV-2 infection. US Centers for Disease Control and Prevention... read more

Fluid Accumulation Syndrome in Sepsis and Septic Shock

In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more

The Hidden Value of MRI: Modifying Treatment Decisions in C-spine Injuries

This study provides a critical evaluation of the implications of additional magnetic resonance imaging (MRI) use in the diagnosis of c-spine injuries. We have demonstrated that an adjunctive MRI extends patients' ED stays,... read more

Genetic Testing in Early-onset Atrial Fibrillation

Atrial fibrillation (AF) is a globally prevalent cardiac arrhythmia with significant genetic underpinnings, as highlighted by recent large-scale genetic studies. A prominent clinical and genetic overlap exists between... read more

Prevalence and Survival of Prolonged VV ECMO for ARDS

The understanding of prolonged venovenous extracorporeal membrane oxygenation (VV ECMO) in the setting of acute respiratory distress syndrome (ARDS) is evolving and durations of support once considered extreme are now commonplace.... read more

The Existence of Adrenal Insufficiency in COVID-19 Patients with Pneumonia

Patients with a history of COVID-19 pneumonia who present with clinical symptoms such as shock, nausea, vomiting, and fatigue should have hypocortisolism included in the differential diagnosis. These patients should also... read more

Lung Ultrasound for Diagnosis and Management of ARDS

Lung ultrasonography (LUS) is essential for diagnosing and managing adult respiratory distress syndrome (ARDS) due to its bedside accessibility and availability across different resource settings. It aids in diagnosis and... read more

Lung Ultrasound for Diagnosis and Management of ARDS

Diagnosing Sepsis: Where We’re At And Where We’re Going

Diagnosing sepsis remains problematic. Pathogen identification is frequently lacking and the dysregulated host response is non-specific. Blood cultures often take days to deliver a result and, even then, approximately 90%... read more

Diagnosing Sepsis: Where We’re At And Where We’re Going

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Major traumatic hemorrhage is potentially preventable with rapid hemorrhage control and improved resuscitation techniques. The time from injury to hospital, resuscitation, diagnosis, and definitive bleeding control should... read more

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences