Insight into ECMO, mortality and ARDS

Insight into ECMO, mortality and ARDS

ARDS is a severe disease with a high mortality rate despite ECLS therapy. Although endpoints and timing of the evaluations differed from those of the CESAR and EOLIA studies and the Extracorporeal Life Support Organization... read more

EROCA: Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport

EROCA: Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport

Outcomes of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest depend on time to therapy initiation. We hypothesize that it would be feasible to select refractory out-of-hospital cardiac... read more

Timing, Outcome, and Risk Factors of Intracranial Hemorrhage in ARDS Patients During VV-ECMO

Timing, Outcome, and Risk Factors of Intracranial Hemorrhage in ARDS Patients During VV-ECMO

Intracranial hemorrhage occurs early during venovenous extracorporeal membrane oxygenation (VV-ECMO) and is a determinant for 60-day mortality. Appropriate adjustment of identified modifiable risk factors might lower... read more

Tocilizumorelikeit? The latest data on Tocilizumab

Tocilizumorelikeit? The latest data on Tocilizumab

Our hats were then blown away when the REMAP-CAP team and the UK government fired an evidence-based carpet bomb in our direction. We saw a trial press release, a preprint article, an alert letter from the MHRA/DHSC, national... read more

ECMO in the Adult Patient (Core Critical Care)

ECMO in the Adult Patient (Core Critical Care)

Extracorporeal membrane oxygenation (ECMO) is developing rapidly, and is now part of the toolkit for the management of all patients with severe respiratory or cardiac failure. Clinicians of all disciplines are in need of... read more

ECMO for COVID-19 patients in Europe and Israel

ECMO for COVID-19 patients in Europe and Israel

As of October 17th the novel coronavirus (SARS-CoV-2) caused a pandemic disease (coronavirus disease 2019, COVID-19) 40 million people worldwide, with almost one million deaths. Although most patients have an uncomplicated... read more

Trauma ICU Rounds – The rEVOLUTION of ECMO

Trauma ICU Rounds – The rEVOLUTION of ECMO

What are the indications for ECMO beyond ARDS and refractory cardiogenic shock? In which patients should we consider eCPR and is this the new standard of care for patients sustaining out-of-hospital cardiac arrest? Finally,... read more

Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous ECMO

Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous ECMO

Among venovenous extracorporeal membrane oxygenation patients in the Extracorporeal Life Support Organization registry, approximately 5% had acute brain injury. Mortality rates increased two-fold when ischemic or hemorrhagic... read more

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

The clinical utilization of extracorporeal membrane oxygenation (ECMO) has seen remarkable expansion since its inception in the early 1970s, including a period of exponential growth in the United States. Venoarterial... read more

Extracorporeal Membrane Oxygenation for COVID-19

Extracorporeal Membrane Oxygenation for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed... read more

Prediction of Neurological Outcomes in Patients Treated With ECPR

Prediction of Neurological Outcomes in Patients Treated With ECPR

This prognostic study develops and validates a prediction model for neurological outcomes of patients with out-of-hospital cardiac arrest with shockable rhythm treated with extracorporeal cardiopulmonary resuscitation. A... read more

Improved Oxygenation After Prone Positioning May Be a Predictor of Survival in Patients With ARDS

Improved Oxygenation After Prone Positioning May Be a Predictor of Survival in Patients With ARDS

We found a significant difference in the Pao2:Fio2 ratio after the first prone positioning between ICU survivors and nonsurvivors. The improvement in oxygenation after the first prone positioning was a significant predictor... read more

The Feasibility of Studying Metabolites in PICU MODS

The Feasibility of Studying Metabolites in PICU MODS

Metabolites are generated from critical biological functions and metabolism. This pediatric study reviewed plasma metabolites in patients suffering from multi-organ dysfunction syndrome (MODS) in the pediatric intensive care... read more

Will the asthma revolution fostered by biologics also benefit adult ICU patients?

Will the asthma revolution fostered by biologics also benefit adult ICU patients?

Asthma exacerbations are inflammatory events that rarely result in full hospitalization following an ER visit. Unfortunately, certain patients require prolonged support, including occasional external lung support through... read more