Tag: glucose
Intensive vs. Conventional Glucose Control in Critically Ill Patients
n this large, international, randomized trial, we found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did... read more
What constitutes optimal glucose management in Critical Care?
Glycaemic Control in the EU. Following on from the poster we presented at the Intensive Care Society. We asked Sphere Medical's own Dr Gavin Troughton to present at our launch event. In the below video he goes into more... read more
Glycaemic Control Targets After TBI
This meta-analysis of intensive glycaemic control shows no association with reduced mortality in TBI. Intensive glucose control showed a borderline significant reduction in the risk of poor neurological outcome, but markedly... read more
A comparison of two insulin infusion protocols in the ICU by continuous glucose monitoring
The Yale protocol provided better average glycemia, more time spent in normoglycemia, less time in hypoglycemia, and less glycemic variability than the Leuven protocol, but was not independently associated with strict glycemic... read more
Performance of a Modern Glucose Meter in ICU
Performance of a Modern Glucose Meter in ICU and General Hospital Inpatients: 3 Years of Real-World Paired Meter and Central Laboratory Results. Due to accuracy concerns, the Food and Drug Administration issued guidance to... read more
The Association of Early Combined Lactate and Glucose Levels with Subsequent Renal and Liver Dysfunction
Abnormal combined lactate and glucose measurements may provide an early indication of organ dysfunction. In critically ill patients a 'normal' glucose with an elevated lactate should not be considered desirable, as this combination... read more
Hyperglycaemia in Critically Ill Patients
There is an ongoing debate regarding the efficacy of glycaemic control in critically ill patients. Here we briefly highlight the key function of elevated glucose in critically ill patients, namely, to enable elevation of... read more
Airway glucose homeostasis: a new target in the prevention and treatment of pulmonary infection
In health, the glucose concentration of airway surface liquid (ASL) is 0.4mM, around 12 times lower than blood glucose concentration. Airway glucose homeostasis is a set of processes that actively maintain low ASL glucose... read more
The Current State of Glycaemic Control Practice
Study involving intensivists from 90 ICUs in northwest Europe confirms significant variability in glycaemic control practices. The study confirmed that there are still controversies over what constitutes optimal glucose management... read more
Tight Glycemic Control in Critically Ill Children
In multicenter studies, tight glycemic control targeting a normal blood glucose level has not been shown to improve outcomes in critically ill adults or children after cardiac surgery. Studies involving critically ill children... read more
Sleep Duration Correlated with Lower Odds of Hyperglycemia
For hospitalized patients, additional sleep and increased sleep efficiency correlate with lower odds of hyperglycemia and impaired fasting glucose. The researchers found that 34 percent of the participants had diabetes, and... read more
Neuroprotective Effects of the Glucagon-Like Peptide-1 Analog Exenatide After Out-of-Hospital Cardiac Arrest
Acute administration of exenatide to comatose patients in the ICU after OHCA is feasible and safe. Exenatide did not reduce neuron-specific enolase levels and did not significantly improve a composite end point of death and... read more
Hypernatremia (Uggggh!)
Hyponatremia has become a little bit sexy. Not so with sodium that is too high. But I’ve seen a bunch of less than ideal management of hypernatremia, so I figured it is time to put out a podcast about it.... read more
Diabetes monitoring breathalyzer developed
A new hand-held breathalyzer that allows individuals to easily assess their blood glucose levels has been developed. The device informs the user bout diabetes risk and it differs from a medical device we reported on earlier... read more
Low Blood Glucose Levels In Hospitalized Patients Linked To Increased Mortality Risk
Mortality risk was higher in insulin-treated patients with moderate hypoglycemia (40-70 mg/dL), compared to patients without insulin treatment with similar glucose values.... read more
Insulin resistance reversed by removal of protein
By removing the protein galectin-3 (Gal3), a team of investigators led by University of California School of Medicine researchers were able to reverse diabetic insulin resistance and glucose intolerance in mouse models of... read more
Dose of dextrose gel lowers risk of low blood sugar in newborns
A single dose of dextrose gel, rubbed inside a newborn's mouth an hour after birth, can lower their risk of developing neonatal hypoglycaemia.... read more
