Cardiac Damage in Patients Infected with Different COVID-19 Variants of Concern

Coronavirus Disease 2019 causes significant morbidity, and different variants of concern (VOCs) can impact organ systems differently. We conducted a single-center retrospective cohort analysis comparing biomarkers and... read more

Pulmonary Hypertension: Basic Science to Clinical Medicine

Pulmonary Hypertension: Basic Science to Clinical Medicine

This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles... read more

Optimizing ICU Weaning: Globalizing Personalized Weaning Strategies

this study provides compelling evidence supporting the concept of individualized weaning in the ICU. By tailoring spontaneous breathing trial (SBT) methods to match specific patient conditions, it represents an essential... read more

The Beta-Blocker Story: Getting It Right

The Beta-Blocker Story: Getting It Right

The idea of using beta-blockers as a treatment for ventricular fibrillation occurred to James Black over 60 years ago. He developed propranolol and cimetidine, among other pharmacologic agents, work for which he won the Nobel... read more

Effects of Surgery on Hemodynamics and Postoperative Delirium in Stanford Type A Aortic Dissection

The results of this study indicate that surgical intervention has a significant effect on improving patients’ hemodynamic parameters, with postoperative MAAD and LVEDd reduced compared to preoperative levels, while LVEF... read more

Pulmonary Hypertension: Controversial and Emerging Topics

Pulmonary Hypertension: Controversial and Emerging Topics

This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with... read more

COPD: Heterogeneity and Personalized Treatment

COPD: Heterogeneity and Personalized Treatment

This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more

Adult Critical Care Medicine

Adult Critical Care Medicine

This clinical casebook provides a comprehensive yet concise state-of-the-art review of adult critical care medicine. Presented in a case-based format, each case focuses on a scenario commonly encountered with an adult patient... read more

Influenza-Complicated Thromboembolism in the ICU

Influenza-complicated thromboembolism (TE) among patients with severe influenza infection in the intensive care unit (ICU) is associated with increased risk for longer- duration mechanical ventilation, longer ICU stays, and... read more

Veno-Arterial-Venous ECMO in a Patient Undergoing Dialysis and Having Cardiopulmonary Failure Due to COVID-19

COVID-19 can cause cardiomyopathy, a rare cardiovascular disorder that can lead to cardiogenic shock. The cardiac and respiratory symptoms may not occur simultaneously, and it is possible to switch to veno-arterial-venous... read more

Comorbid Burden at ICU Admission in COVID-19 vs. Sepsis and ARDS

The burden of age and comorbidity is more prominent in ICU-admission for sepsis and acute respiratory distress syndrome (ARDS) than for COVID-19. This is likely to be caused by a combination of COVID-19 affecting the relatively... read more

Prevalence and Risk Factors of ICU-acquired Weakness in COVID-19 Patients

The prevalence of ICUAW in patients with COVID-19 was considered relatively high. Older age, pre-existing hypertension, medical intervention of prone position, NMBA use, needed tracheostomy and RRT were likely risk factors.... read more

Cardiac Arrest Following Prone Positioning

The complications that can arise from the prone position are often underestimated. Proceduralists, surgeons, and anesthesiologists need to be thoroughly knowledgeable about the common physiological changes that can occur... read more

Using Diuretic Therapy in the Critically Ill Patient

Using Diuretic Therapy in the Critically Ill Patient

Diuretics are routinely prescribed in critically ill patients but significant variation in practice exists. In this article, we summarize current data relevant to diuretic prescribing. What are the indications for diuretics... read more

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more

Hyperlipidemia in Immune Thrombocytopenia

Hyperlipidemia in Immune Thrombocytopenia

A high proportion of ITP patients suffered from metabolic disorders, especially hyperlipidemia. Patients with hyperlipidemia may have more severe bleeding symptoms and worse responses to ITP treatments. Statin may help... read more

The Hemodynamics of Adrenal Veins with Four-dimensional CT Using Quantitative Time-density Curve

The Hemodynamics of Adrenal Veins with Four-dimensional CT Using Quantitative Time-density Curve

Present study quantitatively analyzed adrenal venous flow using four-dimensional computed tomography (4D CT). We reviewed 4D CT images of 55 patients [mean age, 52 years ± 11 (standard deviation); 23 females] who underwent... read more