Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI)

Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI)

In a comprehensive multinational study, approximately one in five patients develop PO-AKI after major surgery. Increasing severity of PO-AKI is associated with a progressive increase in adverse outcomes. Our findings indicate... read more

Hypercalcemia of Immobility in Critically Ill Patients

Hypercalcemia of Immobility in Critically Ill Patients

Significant hypercalcemia can occur in intensive care unit (ICU) patients. Immobilization hypercalcemia has been infrequently reported after ICU admission. Patients, therefore, usually require extensive workup to rule out... read more

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Right ventricular failure (RVF) is a leading driver of morbidity and mortality after major cardiac surgery for advanced heart failure, including orthotopic heart transplantation and left ventricular assist device implantation.... read more

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

In this prospective study of children who received CPR in intensive care units, a pre-existing diagnosis pulmonary hypertension was present in 16% of children but was not associated with statistically significant differences... read more

Hemodialysis as an Effective Treatment for Combined Amlodipine and Metformin Overdose

Hemodialysis as an Effective Treatment for Combined Amlodipine and Metformin Overdose

Introducing emergency dialysis will lead to significant outcomes in mortality and morbidity in patients with combined toxicity of amlodipine and metformin. Moreover, non-ST elevation myocardial infarction is also expected... read more

Severe Hypertriglyceridemia: A 10-Year Review

Severe Hypertriglyceridemia: A 10-Year Review

This study shows the morbidity profile associated with severe hypertriglyceridemia (SHTG), with a high level of ICU admissions and also a high level of the use of plasmapheresis. In our population, this approach had good... read more

Patients With PAH Face Unique Considerations for Lung Transplantation

Patients With PAH Face Unique Considerations for Lung Transplantation

Insights from a new paper outline the unique considerations and management approaches for patients with pulmonary arterial hypertension (PAH) undergoing lung transplantation. Currently approved treatment options for Group... read more

Coronary Sinus Value During CTPA for Predicting Pulmonary Hypertension in Patients with Acute Pulmonary Embolism

Coronary Sinus Value During CTPA for Predicting Pulmonary Hypertension in Patients with Acute Pulmonary Embolism

The coronary sinus ostium area (CSOA) and coronary sinus ostium diameter (CSOD) demonstrated a good ability to predict PH. However, the CSOA exhibited a better performance for predicting development of PASP >30 mmHg. CSOA... read more

Significant Persistent Pain Symptoms After Critical Care Illness

Significant Persistent Pain Symptoms After Critical Care Illness

Persistent pain could be a common health problem after critical illness care. Our data also suggest that there is a lack of specific follow-up after ICU discharge. Given the major consequences on patient quality of life,... read more

Acute Ischemic Stroke: Recent Advances in Reperfusion Treatment

Acute Ischemic Stroke: Recent Advances in Reperfusion Treatment

Stroke is a major clinical challenge. The authors note that during the last 5–7 years, tremendous progress was achieved in the reperfusion treatment of acute ischemic stroke during its first few hours from symptom onset.... read more

Acute Effects of Ketamine on ICP in Children With Severe TBI

Acute Effects of Ketamine on ICP in Children With Severe TBI

In this retrospective, exploratory study, intracranial pressure (ICP) did not increase following ketamine administration. In the setting of a guidelines-based protocol, ketamine was associated with a reduction in ICP during... read more

Intracranial Pressure: Current Perspectives on Physiology and Monitoring

Intracranial Pressure: Current Perspectives on Physiology and Monitoring

Intracranial pressure (ICP) monitoring is now viewed as integral to the clinical care of many life-threatening brain insults, such as severe traumatic brain injury, subarachnoid hemorrhage, and malignant stroke. It serves... read more

Perioperative Management of Antithrombotic Therapy

Perioperative Management of Antithrombotic Therapy

Substantial new evidence has emerged since the 2012 iteration of these guidelines, especially to inform best practices for the perioperative management of patients who are receiving a VKA and may require heparin bridging,... read more

Intra-Abdominal Hypertension – Core Critical Care

Intra-Abdominal Hypertension – Core Critical Care

The most popular book at ISICEM meeting. Despite increasing interest in intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) as causes of significant morbidity and mortality among the critically ill,... read more

General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke

General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke

The functional outcomes 3 months after endovascular treatment for stroke were similar with general anesthesia and sedation. Our results, therefore, suggest that clinicians can use either approach. Of 351 randomized patients,... read more

Acute Kidney Injury Related to Intoxication From Synthetic Cannabis

Acute Kidney Injury Related to Intoxication From Synthetic Cannabis

Acute kidney injury (AKI) occurs infrequently in young patients and often raises concern for irreversible or deadly etiologies. However, AKI related to synthetic marijuana, colloquially known as K2, is an increasingly common... read more

POCUS and Digital Tomosynthesis Correlation When Used with COVID-19 Pneumonia Patients

POCUS and Digital Tomosynthesis Correlation When Used with COVID-19 Pneumonia Patients

Point-of-care ultrasound (POCUS) in primary care has good sensitivity and specificity when compared to digital tomosynthesis as regards the diagnosis of COVID-19 pneumonia in patients with the clinical suspicion of pulmonary... read more