Tag: hypertension
Oestrogen Inhibition Reverses PAH and Associated Metabolic Defects
Increased oestrogen is a strong epidemiological risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic defects. In addition, oestrogens drive penetrance in mice carrying... read more
Risk of AKI After Intravenous Contrast Media Administration
In the largest well-controlled study of acute kidney injury (AKI) following contrast administration in the ED to date, intravenous contrast was not associated with an increased frequency of acute kidney injury. Rates of acute... read more
Hypertension and Prehypertension Underdiagnosed, Undertreated in U.S. Children
Hypertension and prehypertension in children often go undiagnosed, according to a new study published in Pediatrics. The study focused on children with abnormal blood pressures across the United States.... read more
Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI
Substantial variation was found regarding monitoring and treatment policies in patients with Traumatic Brain Injury (TBI) and intracranial hypertension. The results of this survey indicate a lack of consensus between European... read more
Hyperventilation Therapy for Control of Post-Traumatic Intracranial Hypertension
During traumatic brain injury, intracranial hypertension (ICH) can become a life-threatening condition if it is not managed quickly and adequately. Physicians use therapeutic hyperventilation to reduce elevated intracranial... read more
Protocol-based Invasive Intracranial Pressure Monitoring in Acute Liver Failure
Acute liver failure (ALF) may result in elevated intracranial pressure (ICP). While invasive ICP monitoring (IICPM) may have a role in ALF management, these patients are typically coagulopathic and at risk for intracranial... read more
Focus on Brain Injury – The Staircase Approach
Focus on brain injury, staircase approach for the treatment of intracranial hypertension after TBI. The development of clinical protocols based on both laboratory and clinical data has underpinned the achievements of neurocritical... read more
Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality
Clinical trials have documented that lowering blood pressure reduces cardiovascular disease and premature deaths. However, the optimal target for reduction of systolic blood pressure (SBP) is uncertain. This study suggests... read more
Post Intubation Hypotension: The AH SHITE mnemonic
Here is a crowd sourced approach that will allow most etiologies of post intubation hypotension to be identified: The AH SHITE mnemonic is something that you can quickly run through en route to the patient’s room, or at... read more
Various Factors Linked to Dramatic Drop in Dementia Rates
Dementia rates have dropped dramatically over the last decade or so, according to a report published online November 21 in JAMA Internal Medicine.... read more
One-Third of Hypertension Patients Noncompliant with Therapy
More than 30% of patients with hypertension do not adhere to their antihypertensive drug therapy, according to a new study.... read more
Decompressive craniectomy linked with decreased mortality in TBI
Patients with traumatic brain injury (TBI) and refractory intracranial hypertension following 2 stages of standard therapy who were then randomized to receive decompressive craniectomy had lower rates of mortality and higher... read more
Researchers identify potential new way of treating hypertension
Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years. Researchers at the University of Bristol and Afferent Pharmaceuticals have identified a potential new way of treating high blood... read more
