Prehospital IV Fluid Management in Severely Injured Trauma Patients

Prehospital IV Fluid Management in Severely Injured Trauma Patients

Weak, primarily observational evidence suggests that standard fluid resuscitation has no significant mortality benefit over restricting/withholding IV fluids in the context of severe/hypotensive trauma. This review adds... read more

Clinical Cases in Critical Care

Clinical Cases in Critical Care

In Clinical Cases in Critical Care, the authors explore core clinical topics and basic sciences in a practical and realistic way, and include comprehensive discussions focusing on critically unwell patients with a variety... read more

Improving Intubation Performance with Airway Registries

Improving Intubation Performance with Airway Registries

Airway registries are used as a crucial tool to monitor and improve intubation performance and patient care. ED airway registries inform and document the efficacy of quality improvement initiatives to improve intubation performance... read more

Dexmedetomidine, Almost As Many Uses As There Are Letters

Dexmedetomidine, Almost As Many Uses As There Are Letters

There is literature to support the use of dexmedetomidine in patients with sympathomimetic toxidrome. It may be a reasonable approach to utilize Dex, with or without a bolus, while closely monitoring these patients in an... read more

The CLOVERS Trial: Does Nothing Matter in Sepsis?

The CLOVERS Trial: Does Nothing Matter in Sepsis?

The CLOVERS trials is an open label RCT that did not demonstrate any difference (beneficial or harmful) from using a restrictive fluid strategy over a liberal fluid strategy in sepsis-induced hypotension. Do whatever... read more

The effect of a multi-faceted quality improvement program on paramedic intubation success in the critical care transport environment

The effect of a multi-faceted quality improvement program on paramedic intubation success in the critical care transport environment

A multi-faceted advanced airway management (AAM) quality improvement program (QIP) resulted in statistically significant increase in intubation first pass success rates (FPS) rates and a non-significant improvement in DASH-1A... read more

Improving Outcomes in Patients with Difficult Airways

Improving Outcomes in Patients with Difficult Airways

Evidence indicates that the airway community has successfully conquered the anatomically difficult airway, as these patients are managed safely with a low incidence of morbidity and mortality. In contrast, the literature... read more

Critically Unwell Child Intubation in the ED

Critically Unwell Child Intubation in the ED

Intubation in the pediatric emergency department is scary stuff. For critically ill children who require intubation, it is rarely practiced outside of the critical care unit. With the centralization of services there are... read more

Why Are We Still Talking about ICP and Ketamine?

Why Are We Still Talking about ICP and Ketamine?

A trauma patient required emergent intubation during a recent shift. The altered patient was suspected of having an intracranial bleed. My resident was concerned about rapid onset of hypoxia and other internal injuries causing... read more

Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients

Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients

In patients with arterial hypotension norepinephrine increased end-systolic ventricular elastance and arterial elastance. The effects of norepinephrine on stroke volume depend on baseline ventriculo-arterial coupling. Although... read more

Intraoperative Hypotension and AKI after Noncardiac Surgery in Infants and Children

Intraoperative Hypotension and AKI after Noncardiac Surgery in Infants and Children

In distinct contrast to adults, the authors did not find any association between intraoperative hypotension and postoperative renal injury. Avoiding short periods of hypotension should not be the clinician’s primary concern... read more

Ventilation in Patients with Intra-abdominal Hypertension

Ventilation in Patients with Intra-abdominal Hypertension

The incidence of intra-abdominal hypertension (IAH) is high and still underappreciated by critical care physicians throughout the world. One in four to one in three patients will have IAH on admission, while one out of... read more

The Importance of Accurate Glucose Monitoring in Critically Ill Patients

The Importance of Accurate Glucose Monitoring in Critically Ill Patients

Critically ill patients are not found just in intensive care units, but throughout the hospital: emergency departments, post-anaesthesia care units, operating rooms, and many other environments now care for the critically... read more

Balanced Solution vs. 0.9% Saline Solution Fluid Treatment in Critically Ill Patients

Balanced Solution vs. 0.9% Saline Solution Fluid Treatment in Critically Ill Patients

Among critically ill patients requiring fluid challenges, use of a balanced solution compared with 0.9% saline solution did not significantly reduce 90-day mortality. The findings do not support the use of this balanced... read more

Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension

Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension

In patients having intermediate- to high-risk surgery, computer-assisted individualized hemodynamic management significantly reduces intraoperative hypotension compared to a manually controlled goal-directed approach. All... read more

Cerebral Oxygen Saturation and Autoregulation During Hypotension in Extremely Preterm Infants

Cerebral Oxygen Saturation and Autoregulation During Hypotension in Extremely Preterm Infants

Dopamine had no effect on rScO2 compared to placebo in hypotensive infants. Hypotension and cerebral hypoxia are associated with early intraventricular hemorrhage or death. Prospective cohort study of blinded rScO2 measurements... read more

Cardiorespiratory Compromise in the Perioperative Environment

Cardiorespiratory Compromise in the Perioperative Environment

Perioperative cardiorespiratory compromise is common and goes largely undetected. Predictive cardiorespiratory indices can help in early detection of harmful deviations and guide preemptive treatment. Using continuous... read more