Tag: hypoxemia
Taming the Physiologically Difficult Airway: Safer Intubation in Critically Ill Adults
Tracheal intubation is a frequent and high-risk procedure in critically ill adults, with a global study of nearly 3,000 patients revealing major peri-intubation adverse events in 45% of cases—primarily cardiovascular collapse... read more
Extracorporeal Life Support for Adults
This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more
Survival Shockwave: VV-ECMO Outperforms VA-ECMO in Respiratory Failure
This meta-analysis comparing venovenous (VV-ECMO) and venoarterial (VA-ECMO) extracorporeal membrane oxygenation for respiratory failure, encompassing 3,598 patients across eleven studies, found a significant survival advantage... read more
The Crystal Ball of the ICU: Machine Learning Predicts Who’s Staying and Who’s Not
The PREMIER Study dove into the data of 996 patients experiencing Acute Hypoxemic Respiratory Failure (AHRF) who had been on mechanical ventilation (MV) for at least two days, aiming to develop a reliable way to predict their... read more
Hemodynamics: The Key to Noninvasive Ventilation (NIV) Success
This large multicenter observational study found that hemodynamic instability—defined as needing vasopressor support within 24 hours of starting NIV—was linked to a significantly higher risk of NIV failure. The crucial... read more
Individualizing PEEP in Acute Brain Injury
The consensus is that Positive End-Expiratory Pressure (PEEP) can be safely used in most patients with Acute Brain Injury (ABI), provided its effects on the brain are closely monitored. PEEP Safety and ICP: While PEEP... read more
Increased Driving Pressure During Assisted Ventilation for Hypoxemic Respiratory Failure Is Associated with Lower ICU Survival
Driving pressure is marker of severity and a possible target for lung protection during controlled ventilation, but its value during assisted ventilation is unknown. Inspiratory holds provide an estimate of driving pressure... read more
Weaning Failure Prediction Using Electrocardiographic Time-frequency Analysis and Respiration Flow Signals
Weaning patients from mechanical ventilation (MV) is a crucial process that requires meticulous assessment of their ability to breathe independently without ventilatory assistance. Spontaneous breathing test (SBT) is... read more
NHF Oxygen During Apnoea on Hypoxemia and Intubation Success in Pediatric Emergency and ICU
The use of nasal high-flow (NHF) during emergency intubation in children did not result in a reduction in hypoxemic events or an increase in the frequency of successful intubation on the first attempt. However, in the... read more
Nebulized Long-Acting Bronchodilators to Treat ARF in an Older Patients
Although long-acting bronchodilators are not approved to treat acute respiratory failure (ARF), the older adult in this case clinically improved after three doses of revefenacin and arformoterol. Additional studies are... read more
Early Weaning From Invasive Mechanical Ventilation via HFNO vs. Conventional Weaning in ARF Patients
In patients with resolving acute hypoxemic respiratory failure (ARF), early extubation with high flow nasal oxygen is feasible and provides a better alternative to conventional weaning from invasive mechanical ventilation,... read more
Atypical Presentation of Pulmonary Embolism in Patients with Refractory Hypoxemia and Dyspnea
Pulmonary embolism (PE) should be strongly considered in patients presenting with refractory hypoxemia and dyspnea, even in the absence of clinical signs of deep vein thrombosis (DVT). This study highlights the importance... read more
The Advanced Ventilator Book
The Advanced Ventilator Book is a companion to the best-selling The Ventilator Book and is written for clinicians who already have a solid foundation in the basics of mechanical ventilation. It goes beyond the ventilator... read more
Textbook of Ventilation, Fluids, Electrolytes and Blood Gases
The Textbook of Ventilation, Fluids, Electrolytes and Blood Gases encompass essential topics for which thorough education and training is a must for any clinician who manages these patients. This book has four sections, each... read more
Establishment and Validation of a Risk Prediction Model for Sepsis-Associated Liver Injury in ICU Patients
This novel nomogram effectively predicts SALI risk in sepsis patients by integrating readily available clinical parameters. While external validation is needed, the model shows promise as a practical tool for early risk stratification,... read more
Toward Precision Medicine in ARF
Acute hypoxemic respiratory failure (AHRF) is one of the leading causes A for admission to the ICU. Acute respiratory failure (ARF) is defined as the inability of the respiratory system to meet the oxygenation and ventilation... read more
Evaluation Effects of Nebulized Hypertonic Saline and Nebulized Corticosteroids in Patients with ARDS
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute respiratory failure as a result of diffuse lung inflammation and oedema manifested by hypoxemia and stiffness in the lungs. This study... read more
Mini Bronchoalveolar Lavage vs. Endo-Tracheal Aspirate in Diagnosing Bacterial Pneumonia in ICU
This study supports the use of endotracheal aspirate (ETA) as a cost-effective and efficient alternative to mBAL for the diagnosis of pneumonia in intubated ICU patients, particularly in settings where resources are limited.... read more
Oxygenation Indices and Early Prediction of Outcome in Hypoxemic Patients with COVID-19 Pneumonia Requiring NIV Respiratory Support in Pulmonary Intermediate Care Unit
Oxygenation indices (OI) showed different effectiveness in predicting NIRT failure within 24 h of treatment in COVID-19 related pneumonia. This may be due to the multi-factorial pathophysiology of hypoxemia. Our study... read more
Impacts of Initial ICU Driving Pressure on Outcomes in Acute Hypoxemic Respiratory Failure
Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory distress syndrome (ARDS) and has a strong association with outcome. However, it is uncertain whether limiting DP can reduce... read more
Risk Factors for Secondary Organizing Pneumonia and Acute Fibrinous and Organizing Pneumonia in Patients with COVID-19 Pneumonia
Based on our findings, we observed that age ≥50 years, diabetes mellitus, and severe hypoxemia on admission (SpO2 ... read more
The Pathophysiology of Happy Hypoxemia in COVID-19
The novel coronavirus disease 2019 (COVID-19) pandemic is a global crisis, challenging healthcare systems worldwide. Many patients present with a remarkable disconnect in rest between profound hypoxemia yet without proportional... read more
