Extracorporeal Life Support for Adults

This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more

Extracorporeal Life Support for Adults

EEG Patterns for Predicting Poor Outcome After Cardiac Arrest

The specificity of the ERC-ESICM-recommended EEG patterns for predicting poor outcome after cardiac arrest exceeds 90% but is lower than in previous studies, suggesting that large-scale implementation may reduce their accuracy.... read more

EEG Patterns for Predicting Poor Outcome After Cardiac Arrest

Dyspnea and Dyspnea-Associated Anxiety in ICU Patients

Dyspnea is frequently associated with anxiety, prolonged days on mechanical ventilation, and worse quality of life after discharge. It can also increase the risk of posttraumatic stress disorder post ICU discharge. However,... read more

Dyspnea and Dyspnea-Associated Anxiety in ICU Patients

Heat Shock Protein 27 in COVID-19 and non-COVID ARDS Pathogenesis

Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure in intensive care units that has increased dramatically as a result of the COVID-19 pandemic. In both COVID-19 and non-COVID... read more

Heat Shock Protein 27 in COVID-19 and non-COVID ARDS Pathogenesis

Pediatric Sepsis Phenotype with Persistent Hypoxemia, Encephalopathy, and Shock

We derived and validated the persistent hypoxemia, encephalopathy, and shock phenotype, which is highly reproducible, clinically relevant, and associated with HTE to common adjuvant therapies in children with sepsis. We... read more

Pediatric Sepsis Phenotype with Persistent Hypoxemia, Encephalopathy, and Shock

HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU

Acute hypoxic respiratory failure in coronavirus disease 2019 (COVID-19) pneumonia has been treated with oxygen delivered by oxygen masks and non-invasive ventilation (NIV) with continuous positive airway pressure (CPAP),... read more

HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU

Tracheal Intubation of Critically Ill Adults: Video vs. Direct Laryngoscopy

Successful intubation on the first attempt occurred in 600 out of 705 patients (85.1%) in the video-laryngoscope group and 504 out of 712 (70.8%) in the direct-laryngoscope group (ARR, 14.3%; 95% CI, 9.9 to 18.7; p... read more

Tracheal Intubation of Critically Ill Adults: Video vs. Direct Laryngoscopy

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Iatrogenic Hypoxemia and Atrial Septal Defect Due to Electrical Storm Ablation After Left Ventricular Assist Device

Predominant strategies for the management of electrical storm include antiarrhythmic medical therapy, beta-blockers, and catheter ablation. Some studies have demonstrated refractory electrical storm managed with mechanical... read more

Iatrogenic Hypoxemia and Atrial Septal Defect Due to Electrical Storm Ablation After Left Ventricular Assist Device

Acute Respiratory Distress Syndrome: Advances in Diagnostic Tools and Disease Management

Divided into thirteen chapters, this book provides a wealth of research-oriented findings and practical guidance, ranging from the definition, epidemiology and pathophysiology, to the diagnosis and management of the disease.... read more

Acute Respiratory Distress Syndrome: Advances in Diagnostic Tools and Disease Management

Association Between Oxygen Desaturation Index and Cardiovascular Disease in Non-Sleepy SDB Subtype

In the Chinese community-dwelling population, non-sleepy sleep-disordered breathing (SDB) was highly prevalent. Oxygen desaturation index (ODI), an easily extracted indicator from a type IV sleep monitor, most strongly reflected... read more

Association Between Oxygen Desaturation Index and Cardiovascular Disease in Non-Sleepy SDB Subtype

Mechanical Ventilation: For Fun and Benefit

Illustrated and explained simply this book is for anyone that works in an intensive care unit - residents, pulmonary/critical care fellows, therapists, or nurses who wants a better understanding of mechanical ventilation. Easy... read more

Mechanical Ventilation: For Fun and Benefit

Bougie vs. Endotracheal Tube with Stylet on Successful Intubation

Among critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful intubation on the first attempt compared with use of an endotracheal tube with stylet. Among... read more

Bougie vs. Endotracheal Tube with Stylet on Successful Intubation

Feed Intolerance Reversal by Prokinetics Improves Survival in Critically Ill Cirrhosis Patients

Feed intolerance (FI) is common in critically-ill cirrhosis patients and non-resolution carries high mortality. Early recognition and treatment with prokinetics is recommended to improve short-term survival. Of the 1,030... read more

Feed Intolerance Reversal by Prokinetics Improves Survival in Critically Ill Cirrhosis Patients

Improving Outcomes in Patients with Difficult Airways

Evidence indicates that the airway community has successfully conquered the anatomically difficult airway, as these patients are managed safely with a low incidence of morbidity and mortality. In contrast, the literature... read more

Improving Outcomes in Patients with Difficult Airways

Prone Position in Mechanically Ventilated Patients

The use of prone position (PP) during invasive mechanical ventilation was first reported more than 45 years ago as a mean to improve oxygenation in patients with acute hypoxemic respiratory failure. Improved oxygenation... read more

Prone Position in Mechanically Ventilated Patients

Lower vs. Higher Oxygenation Targets in ICU Patients with Severe Hypoxemia

Among adult ICU patients with severe hypoxemia, a lower oxygenation target (8 kPa) did not improve survival or HRQoL at 1 year as compared to a higher oxygenation target (12 kPa). We obtained 1‑year vital status for... read more

Lower vs. Higher Oxygenation Targets in ICU Patients with Severe Hypoxemia

Arterial Carbon Dioxide and Acute Brain Injury in VA-ECMO

Acute brain injury (ABI) occurs frequently in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). We examined the association between peri-cannulation arterial carbon dioxide tension (PaCO2) and... read more

Arterial Carbon Dioxide and Acute Brain Injury in VA-ECMO