Tag: hypoxemia
Dyspnea and Dyspnea-Associated Anxiety in ICU Patients
Dyspnea is frequently associated with anxiety, prolonged days on mechanical ventilation, and worse quality of life after discharge. It can also increase the risk of posttraumatic stress disorder post ICU discharge. However,... read more
Heat Shock Protein 27 in COVID-19 and non-COVID ARDS Pathogenesis
Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure in intensive care units that has increased dramatically as a result of the COVID-19 pandemic. In both COVID-19 and non-COVID... read more
Pediatric Sepsis Phenotype with Persistent Hypoxemia, Encephalopathy, and Shock
We derived and validated the persistent hypoxemia, encephalopathy, and shock phenotype, which is highly reproducible, clinically relevant, and associated with HTE to common adjuvant therapies in children with sepsis. We... read more
HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU
Acute hypoxic respiratory failure in coronavirus disease 2019 (COVID-19) pneumonia has been treated with oxygen delivered by oxygen masks and non-invasive ventilation (NIV) with continuous positive airway pressure (CPAP),... read more
Tracheal Intubation of Critically Ill Adults: Video vs. Direct Laryngoscopy
Successful intubation on the first attempt occurred in 600 out of 705 patients (85.1%) in the video-laryngoscope group and 504 out of 712 (70.8%) in the direct-laryngoscope group (ARR, 14.3%; 95% CI, 9.9 to 18.7; p... read more
Verticalization Therapy for ARDS Patients Receiving VV-ECMO
Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more
Iatrogenic Hypoxemia and Atrial Septal Defect Due to Electrical Storm Ablation After Left Ventricular Assist Device
Predominant strategies for the management of electrical storm include antiarrhythmic medical therapy, beta-blockers, and catheter ablation. Some studies have demonstrated refractory electrical storm managed with mechanical... read more
Acute Respiratory Distress Syndrome: Advances in Diagnostic Tools and Disease Management
Divided into thirteen chapters, this book provides a wealth of research-oriented findings and practical guidance, ranging from the definition, epidemiology and pathophysiology, to the diagnosis and management of the disease.... read more
Association Between Oxygen Desaturation Index and Cardiovascular Disease in Non-Sleepy SDB Subtype
In the Chinese community-dwelling population, non-sleepy sleep-disordered breathing (SDB) was highly prevalent. Oxygen desaturation index (ODI), an easily extracted indicator from a type IV sleep monitor, most strongly reflected... read more
Mechanical Ventilation: For Fun and Benefit
Illustrated and explained simply this book is for anyone that works in an intensive care unit - residents, pulmonary/critical care fellows, therapists, or nurses who wants a better understanding of mechanical ventilation. Easy... read more
Bougie vs. Endotracheal Tube with Stylet on Successful Intubation
Among critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful intubation on the first attempt compared with use of an endotracheal tube with stylet. Among... read more
Feed Intolerance Reversal by Prokinetics Improves Survival in Critically Ill Cirrhosis Patients
Feed intolerance (FI) is common in critically-ill cirrhosis patients and non-resolution carries high mortality. Early recognition and treatment with prokinetics is recommended to improve short-term survival. Of the 1,030... read more
Improving Outcomes in Patients with Difficult Airways
Evidence indicates that the airway community has successfully conquered the anatomically difficult airway, as these patients are managed safely with a low incidence of morbidity and mortality. In contrast, the literature... read more
Prone Position in Mechanically Ventilated Patients
The use of prone position (PP) during invasive mechanical ventilation was first reported more than 45 years ago as a mean to improve oxygenation in patients with acute hypoxemic respiratory failure. Improved oxygenation... read more
Lower vs. Higher Oxygenation Targets in ICU Patients with Severe Hypoxemia
Among adult ICU patients with severe hypoxemia, a lower oxygenation target (8 kPa) did not improve survival or HRQoL at 1 year as compared to a higher oxygenation target (12 kPa). We obtained 1‑year vital status for... read more
Arterial Carbon Dioxide and Acute Brain Injury in VA-ECMO
Acute brain injury (ABI) occurs frequently in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). We examined the association between peri-cannulation arterial carbon dioxide tension (PaCO2) and... read more
Critical COVID-19 Pneumonia Determinants
SARS-CoV-2 infection is benign in most individuals but, in approx. 10% of cases, it triggers hypoxemic COVID-19 pneumonia, which becomes critical in ˜3% of cases. The ensuing risk of death (˜1%) doubles every five years... read more
Treating Hypoxia in Discharged COVID-19 Patients
The ICU technique of placing a hypoxic patient in a prone position is being widely used to care for COVID-19 patients in respiratory distress to improve oxygenation and possibly to avoid intubation. The COVID-19 pandemic... read more
Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia
In unresolving COVID-19 pneumonia, the respiratory mechanics and the gas-exchange response to prone positioning and recruitment largely depend on the following two factors: perfusion dysregulation and the amount of consolidated... read more
HIV and COVID-19 Increased Risk of Severe Outcomes
People living with HIV with detectable HIV viraemia, chronic comorbidities, and some subpopulations could be at increased risk of severe outcomes from COVID-19. These groups should be prioritised in clinical management and... read more
ARDS vs. PseudoARDS – Failure of the Berlin Definition
True ARDS might be defined as a histological diagnosis involving diffuse alveolar damage throughout the lungs (characterized by hyaline membrane formation and thickening of the alveolar walls). PseudoARDS refers to patients... read more
