Essentials of Neurosurgical Anesthesia & Critical Care

This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important... read more

Essentials of Neurosurgical Anesthesia & Critical Care

Emergency ECMO Deployment During Liver Transplantation in POPH Patients

Portopulmonary hypertension (POPH) is a challenge in the perioperative setting. Orthotopic liver transplantation (OLT) is a therapeutic option in that setting. ECMO may be necessary for patients with POPH in the perioperative... read more

Primary Management of Polytrauma

This well-illustrated book describes a practical approach to the primary management of patients who have multiple injuries, or polytrauma, with the aim of providing medical and paramedical personnel with the knowledge required... read more

Primary Management of Polytrauma

Ventilator Associated Pneumonia in ICU: Identification, Evaluation and Prevention

This study highlights the significant prevalence of Pseudomonas aeruginosa (PA) as a major bacterial pathogen causing ventilator-associated pneumonia (VAP) in ICU patients, with a high detection rate of 71.7% in tested patients,... read more

Early Weaning From Invasive Mechanical Ventilation via HFNO vs. Conventional Weaning in ARF Patients

In patients with resolving acute hypoxemic respiratory failure (ARF), early extubation with high flow nasal oxygen is feasible and provides a better alternative to conventional weaning from invasive mechanical ventilation,... read more

New Insights: Mortality in Nosocomial Lower Respiratory Tract Infections

This multicenter, multinational study conducted in Europe and Latin America sheds light on the clinical landscape of nLRTI, which continues to be an essential issue in the context of critical care. We provide insights... read more

ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support

This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS). ICU-AW frequently occurred... read more

Rapid and Accurate Sepsis Identification Using AI

This study demonstrates that by providing streamlined predictions using CBC+DIFF data without requiring extensive clinical parameters, the AI-CDSS can be seamlessly integrated into clinical workflows, enhancing rapid, accurate... read more

New Insights: Inhaled Nitric Oxide in Severe COVID-19 Patients

This study provides novel insights into the use of inhaled nitric oxide in severe ARDS COVID-19 patients. Specifically, we demonstrate that the iNO effect of oxygenation improvement is delayed with a prolonged feature that... read more

CAR-T Therapy – Critical Care Considerations of Chimeric Antigen Receptor

Despite significantly improving the treatment of blood cancers, CAR T-cell therapy still faces significant hurdles due to its complex and varied toxicities, which require ongoing research to optimize management; while understanding... read more

Association Between Early Ondansetron Use and Sepsis Risk in ICU Patients

In both patients with SOFA 3, early ondansetron use was correlated with a reduced risk of sepsis. Patients with early ondansetron use had lower odds of experiencing sepsis than patients without early ondansetron use, which... read more

Code Sepsis – Early Decompensation and Predictors

Early recognition and management of sepsis within the first hour of a sepsis alert is critical for patient survival, requiring healthcare providers to be trained to identify "red flag" symptoms like rapid breathing (tachypnea)... read more

Predicting Sepsis Outcomes – Efficacy of Early Warning Scores

In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments... read more

Rhabdomyolysis Due to Nutritional Supplements Intake

habdomyolysis is a condition characterized by the destruction of muscle cells and subsequent release of it's intracellular contents. It is typically asymptomatic, with moderate creatine kinase elevation. Severe cases... read more

Single Lumen vs. Double Lumen Endotracheal Tube For Postoperative Swallowing Function in Lung Transplantation Patients

BackgroundThis study was conducted to investigate the effect of endotracheal tube type on post operative dysphagia in patients undergoing lung transplant surgery. Will patients who are intubated with a single lumen endotracheal... read more

Approach to Peripheral Neuropathy

Peripheral neuropathy is frequently encountered in the clinical setting by doctors of various specialties. Neuropathies can be approached based on the temporal profile, spatial pattern and pathology. There is a need for... read more

Using Critical Ultrasound To Predict Early Diagnosis of ICU-acquired Weakness in Septic Patients

This study uncovered pivotal indicators for predicting the occurrence of ICUAW in septic patients. Despite no significant difference in age, gender, BMI, BSA, or SOFA scores between the two groups, the significant differences... read more

Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection

Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more

Zosyn vs. Efepime: Which One Is Safer?

While both piperacillin-tazobactam and cefepime are commonly used to treat infections caused by Pseudomonas aeruginosa in hospitalized patients, there is a concern that piperacillin-tazobactam may lead to acute kidney injury... read more

Pleural Drainage, Clinical Characteristics, and Management Strategies in the Perioperative Fontan Patient

Prolonged pleural drainage and chylothorax are common in postoperative Fontan patients and are associated with increased morbidity and mortality. Multiple medical and interventional treatment strategies exist and vary between... read more

Expert Consensus Statements on Lipids in Parenteral Nutrition

Lipids are integral to parenteral nutrition (PN) in all settings where PN is required, serving as a source of energy and essential fatty acids. In addition, lipids modulate a variety of biological functions, including inflammatory... read more

Developing a Rapid Screening Tool for High-risk ICU Sepsis Patients

This study demonstrates that machine learning-based prediction models for sepsis can enhance clinical outcomes through accurate risk assessment during the critical first 24h of ICU admission. Despite healthcare system... read more