Tag: ICU
IFG vs. CBG in Patients with Multiple Organ Failure Requiring Vasopressor Infusion
Interstitial flash glucose (IFG) does not demonstrate either analytical or clinical accuracy to be considered equivalent to capillary blood glucose (CBG) in patients with multiple organ failure who require vasopressor infusion. This... read more
Prediction of AKI in ICU Patients Based on Interpretable Machine Learning
The machine learning model described in this study is capable of accurately predicting the onset of AKI in ICU patients up to 24 hours in advance. Validated within the MIMIC-IV and MIMIC-III databases, the model demonstrates... read more
Intubate Patients with Sepsis Before Midnight or When the Time Comes?
The ever-recurring decision for every clinician is to act or not to act and when to act. The balance of benefit or harm of an intervention and the optimal timing of treatment is not always clear. Intervening or not and... read more
Does AI Close Gaps in Clinical Pharmacology in the ICU?
Artificial intelligence (AI) has the potential to close significant gaps in clinical pharmacology in the ICU. Its applications range from personalized dosing and predictive analytics to clinical trial optimization and education.... read more
Leveraging the Power of Routinely Collected ICU Data
With the steady advent of electronic health records, the abundance of routinely recorded data related to the treatment and care of intensive care unit (ICU) patients can be nothing short of overwhelming. Over tens of... read more
Fluid Bolus Therapy with 20% Albumin vs. Crystalloid-based Regimen
In this trial involving adult patients undergoing cardiac surgery with cardiopulmonary bypass, 20% albumin fluid bolus therapy (FBT) compared to crystalloid FBT did not decrease the occurrence of acute kidney injury (AKI).... read more
New Insights on CRRT for ARDS
In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more
Single-use vs. Multiple-use Endotracheal Suction Catheters Flushed with Chlorhexidine in Mechanically Ventilated ICU Patients
The aim of this feasibility randomized controlled trial (fRCT) is to assess the practicality and impact of using single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine on the incidence of... read more
Immune Cell-Based vs. Albumin-Based Ratios as Outcome Predictors in Critically Ill COVID-19 Patients
This study aimed to assess the prognostic value of an array of biomarkers regarding the likelihood of a lethal outcome in critically ill COVID-19 patients. We took advantage of the opportunity to classify them into immune... read more
Invasive Mechanical Ventilation Strategies For ICU Patients with COVID-19
Lung protective ventilation and prone positioning were used in many of the Danish ICU patients with COVID-19, but barotrauma, prolonged ventilation and death occurred frequently. A total of 774 patients were invasively... read more
Passport to Successful Outcomes for Patients Admitted to ICU: Meeting Patient Goals of Care
The second edition builds upon the previous content, exploring new and emerging evidence to enhance the structure and content of rehabilitation provided. It considers the additional impact of COVID-19 throughout each chapter.... read more
7-day Fluid Balance Associated with Poor Outcomes
The net fluid balance in patients with sepsis 7 days following ICU administration was significantly related to mortality during hospitalization. Specifically, a 7-day fluid balance > 5,240 mL was associated with poor... read more
Establishment and Validation of a Risk Prediction Model for Sepsis-Associated Liver Injury in ICU Patients
This novel nomogram effectively predicts SALI risk in sepsis patients by integrating readily available clinical parameters. While external validation is needed, the model shows promise as a practical tool for early risk stratification,... read more
Lactic Acidosis with Metformin Accumulation in the ICU
Metformin-associated lactic acidosis (MALA) in ICUs often follow acute dehydration or infection, and these high-risk situations must be signals to prevent this serious ADR. Specific education programs for physicians and... read more
Increased Lactate Dehydrogenase to Albumin Ratio Associated with Short-term Mortality in Septic ICU Patients
Elevated lactate dehydrogenase to albumin ratio (LAR) was found to be significantly associated with an increased risk of all-cause mortality at 28 and 90 days in septic patients. LAR was suggested to be promising biomarker... read more
Procalcitonin Correlation with SEPSIS Severity in ICU Patients
High rates of morbidity and death are linked to sepsis, a potentially fatal illness. Procalcitonin (PCT), a biomarker of bacterial infection, is increasingly used in sepsis management to evaluate disease severity and guide... read more
Fast-Track in Cardiac Anesthesia: Cardiac Surgery in the Era of ERAS
This new book, focused on fast-track approaches in cardiac surgery, covers ERAS cardiac guidelines, explores the application of loco-regional anesthesia in cardiac surgery, and addresses all aspects related to early extubation... read more
Bedside Tunneled Dialysis Catheter Program Development and Implementation
The placement of ultrasound guided tunneled dialysis catheters at the bedside following a pre-procedural evaluation of the right jugular, brachiocephalic, and femoral veins is a safe option resulting in expedited patient... read more
Extubation Failure Risk Prediction Model Using Bedside Ultrasound
We have established a risk prediction model for extubation failure in mechanically ventilated ICU patients. This risk model base on bedside ultrasound parameters provides valuable insights for identifying high-risk patients... read more
ECMO vs. Cardiopulmonary Bypass in Lung Transplantation
Extracorporeal membrane oxygenation (ECMO) offers perioperative advantages in lung transplantation, reducing postoperative complications, one-year mortality, and recovery time compared to CPB. However, the longer total ischemic... read more
Successful Treatment of Unilateral Pulmonary Edema as Minimally Invasive Mitral Valve Surgery Complication
We successfully treated this patient using ECMO and independent lung ventilation. Several cases have been described in the literature, but the pathogenesis and risk factors of UPE remain unclear. Management depends on... read more
Plasma Proteome Temporal Changes Associated with Sepsis Mortality
Our proteomics approach revealed significant associations between changes in the plasma proteome within the first days of sepsis and mortality as well as disease severity. We identified and characterised the underlying... read more
