Association Between Early Ondansetron Use and Sepsis Risk in ICU Patients

In both patients with SOFA 3, early ondansetron use was correlated with a reduced risk of sepsis. Patients with early ondansetron use had lower odds of experiencing sepsis than patients without early ondansetron use, which... read more

Code Sepsis – Early Decompensation and Predictors

Early recognition and management of sepsis within the first hour of a sepsis alert is critical for patient survival, requiring healthcare providers to be trained to identify "red flag" symptoms like rapid breathing (tachypnea)... read more

Predicting Sepsis Outcomes – Efficacy of Early Warning Scores

In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments... read more

Rhabdomyolysis Due to Nutritional Supplements Intake

habdomyolysis is a condition characterized by the destruction of muscle cells and subsequent release of it's intracellular contents. It is typically asymptomatic, with moderate creatine kinase elevation. Severe cases... read more

Single Lumen vs. Double Lumen Endotracheal Tube For Postoperative Swallowing Function in Lung Transplantation Patients

BackgroundThis study was conducted to investigate the effect of endotracheal tube type on post operative dysphagia in patients undergoing lung transplant surgery. Will patients who are intubated with a single lumen endotracheal... read more

Approach to Peripheral Neuropathy

Peripheral neuropathy is frequently encountered in the clinical setting by doctors of various specialties. Neuropathies can be approached based on the temporal profile, spatial pattern and pathology. There is a need for... read more

Using Critical Ultrasound To Predict Early Diagnosis of ICU-acquired Weakness in Septic Patients

This study uncovered pivotal indicators for predicting the occurrence of ICUAW in septic patients. Despite no significant difference in age, gender, BMI, BSA, or SOFA scores between the two groups, the significant differences... read more

Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection

Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more

Zosyn vs. Efepime: Which One Is Safer?

While both piperacillin-tazobactam and cefepime are commonly used to treat infections caused by Pseudomonas aeruginosa in hospitalized patients, there is a concern that piperacillin-tazobactam may lead to acute kidney injury... read more

Pleural Drainage, Clinical Characteristics, and Management Strategies in the Perioperative Fontan Patient

Prolonged pleural drainage and chylothorax are common in postoperative Fontan patients and are associated with increased morbidity and mortality. Multiple medical and interventional treatment strategies exist and vary between... read more

Expert Consensus Statements on Lipids in Parenteral Nutrition

Lipids are integral to parenteral nutrition (PN) in all settings where PN is required, serving as a source of energy and essential fatty acids. In addition, lipids modulate a variety of biological functions, including inflammatory... read more

Developing a Rapid Screening Tool for High-risk ICU Sepsis Patients

This study demonstrates that machine learning-based prediction models for sepsis can enhance clinical outcomes through accurate risk assessment during the critical first 24h of ICU admission. Despite healthcare system... read more

Impact of Time to Catheter-Based Therapy on Outcomes in Acute Pulmonary Embolism

Early catheter-based therapie (CBT) was associated with improved clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE). The composite PE shock score may help identify patients who will benefit... read more

Severe Sepsis-associated AKI and Outcomes

These results demonstrate an association between an index episode involving SA-AKI and the composite outcome in a defined population. Identification of this group may allow intensive nephrology follow-up and secondary... read more

High cDPP3 Predicts Mortality and Need for Organ Support in Cardiogenic Shock

The present study confirms that circulating dipeptidyl peptidase 3 (cDPP3) and its kinetics are associated with 30-day mortality and the need for organ support in a large and diverse population of CS. The prognostic value... read more

Predictor of Weaning Outcome Using Sonographic Assessment of Post-intubation Laryngeal Obstruction

The study determined that both cuff leak volume and ultrasound-guided LACWD exhibited excellent sensitivity and specificity in predicting clinically significant upper airway blockage post-extubation, with cuff leak volume... read more

Atypical Presentation of Pulmonary Embolism in Patients with Refractory Hypoxemia and Dyspnea

Pulmonary embolism (PE) should be strongly considered in patients presenting with refractory hypoxemia and dyspnea, even in the absence of clinical signs of deep vein thrombosis (DVT). This study highlights the importance... read more

Transtracheal Ultrasound as a Preventive Tool for Endotracheal Tube Malpositioning in the ICU

Endotracheal tube (ETT) malpositioning can result in a myriad of complications. Daily chest radiographs (CXR) is the gold standard in monitoring these complications. Point-of-care transtracheal ultrasound (TTUS) is an emerging... read more

Should we use AI for writing ICU diaries? Yes!

AI-generated diaries for patients in intensive care units (ICU) may offer smart strategies to convince typical barriers against the use of ICU diaries in practice and have further benefits. However there are different arguments... read more

Implementing Bedside Percutaneous Tracheostomy and PUG Team to Reduce LOS

Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more

Landiolol vs. Esmolol – Efficacy and Safety in Critically Ill Patients

Landiolol provides superior heart rate control in critically ill patients with tachycardia compared to Esmolol, without increasing vasopressor requirements during the first 24 h. Findings from ScvO2 levels and PCO2 gap... read more

Multidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory Status Epilepticus and Nontuberculous Mycobacterial CNS Infections in the ICU

The diagnosis and management of complex neurological conditions such as New-Onset Refractory Status Epilepticus (NORSE) and central nervous system (CNS) infections caused by non-tuberculous mycobacteria (NTM) pose substantial... read more