Impact of Time to Catheter-Based Therapy on Outcomes in Acute Pulmonary Embolism

Early catheter-based therapie (CBT) was associated with improved clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE). The composite PE shock score may help identify patients who will benefit... read more

Severe Sepsis-associated AKI and Outcomes

These results demonstrate an association between an index episode involving SA-AKI and the composite outcome in a defined population. Identification of this group may allow intensive nephrology follow-up and secondary... read more

High cDPP3 Predicts Mortality and Need for Organ Support in Cardiogenic Shock

The present study confirms that circulating dipeptidyl peptidase 3 (cDPP3) and its kinetics are associated with 30-day mortality and the need for organ support in a large and diverse population of CS. The prognostic value... read more

Predictor of Weaning Outcome Using Sonographic Assessment of Post-intubation Laryngeal Obstruction

The study determined that both cuff leak volume and ultrasound-guided LACWD exhibited excellent sensitivity and specificity in predicting clinically significant upper airway blockage post-extubation, with cuff leak volume... read more

Atypical Presentation of Pulmonary Embolism in Patients with Refractory Hypoxemia and Dyspnea

Pulmonary embolism (PE) should be strongly considered in patients presenting with refractory hypoxemia and dyspnea, even in the absence of clinical signs of deep vein thrombosis (DVT). This study highlights the importance... read more

Transtracheal Ultrasound as a Preventive Tool for Endotracheal Tube Malpositioning in the ICU

Endotracheal tube (ETT) malpositioning can result in a myriad of complications. Daily chest radiographs (CXR) is the gold standard in monitoring these complications. Point-of-care transtracheal ultrasound (TTUS) is an emerging... read more

Should we use AI for writing ICU diaries? Yes!

AI-generated diaries for patients in intensive care units (ICU) may offer smart strategies to convince typical barriers against the use of ICU diaries in practice and have further benefits. However there are different arguments... read more

Implementing Bedside Percutaneous Tracheostomy and PUG Team to Reduce LOS

Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more

Landiolol vs. Esmolol – Efficacy and Safety in Critically Ill Patients

Landiolol provides superior heart rate control in critically ill patients with tachycardia compared to Esmolol, without increasing vasopressor requirements during the first 24 h. Findings from ScvO2 levels and PCO2 gap... read more

Multidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory Status Epilepticus and Nontuberculous Mycobacterial CNS Infections in the ICU

The diagnosis and management of complex neurological conditions such as New-Onset Refractory Status Epilepticus (NORSE) and central nervous system (CNS) infections caused by non-tuberculous mycobacteria (NTM) pose substantial... read more

RSV Infection – Epidemiology and Clinical Risk Factors

Respiratory syncytial virus (RSV) infection is the most frequent reason for hospitalization of infants in developed countries. Premature birth without or, especially, with chronic lung disease of prematurity, congenital heart... read more

Hemodynamic Monitoring Made Easy: Mastering Critical Care Skills for Nurses and Clinicians

This thorough, simple-to-follow book was created especially for critical care nurses, clinicians, and other healthcare workers to help you fully utilize hemodynamic monitoring. With its straightforward, methodical approach... read more

Hemodynamic Monitoring Made Easy: Mastering Critical Care Skills for Nurses and Clinicians

Temporal Trends of RSV-Associated US ICU Admissions

Wide variations in regional and seasonal patterns in hospital and ICU admissions were noted in children with respiratory syncytial virus–associated acute respiratory illness across the United States. Results from our... read more

The ICU Survival Book

The ICU Survival Book is a guide for residents, students, advanced practice providers, and critical care nurses who want to learn the basics of critical care medicine. This reference is designed to follow the systems-based... read more

The ICU Survival Book

IFG vs. CBG in Patients with Multiple Organ Failure Requiring Vasopressor Infusion

Interstitial flash glucose (IFG) does not demonstrate either analytical or clinical accuracy to be considered equivalent to capillary blood glucose (CBG) in patients with multiple organ failure who require vasopressor infusion. This... read more

Prediction of AKI in ICU Patients Based on Interpretable Machine Learning

The machine learning model described in this study is capable of accurately predicting the onset of AKI in ICU patients up to 24 hours in advance. Validated within the MIMIC-IV and MIMIC-III databases, the model demonstrates... read more

Intubate Patients with Sepsis Before Midnight or When the Time Comes?

The ever-recurring decision for every clinician is to act or not to act and when to act. The balance of benefit or harm of an intervention and the optimal timing of treatment is not always clear. Intervening or not and... read more

Does AI Close Gaps in Clinical Pharmacology in the ICU?

Artificial intelligence (AI) has the potential to close significant gaps in clinical pharmacology in the ICU. Its applications range from personalized dosing and predictive analytics to clinical trial optimization and education.... read more

Leveraging the Power of Routinely Collected ICU Data

With the steady advent of electronic health records, the abundance of routinely recorded data related to the treatment and care of intensive care unit (ICU) patients can be nothing short of overwhelming. Over tens of... read more

Fluid Bolus Therapy with 20% Albumin vs. Crystalloid-based Regimen

In this trial involving adult patients undergoing cardiac surgery with cardiopulmonary bypass, 20% albumin fluid bolus therapy (FBT) compared to crystalloid FBT did not decrease the occurrence of acute kidney injury (AKI).... read more

New Insights on CRRT for ARDS

In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more

Single-use vs. Multiple-use Endotracheal Suction Catheters Flushed with Chlorhexidine in Mechanically Ventilated ICU Patients

The aim of this feasibility randomized controlled trial (fRCT) is to assess the practicality and impact of using single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine on the incidence of... read more