Immune Cell-Based vs. Albumin-Based Ratios as Outcome Predictors in Critically Ill COVID-19 Patients

This study aimed to assess the prognostic value of an array of biomarkers regarding the likelihood of a lethal outcome in critically ill COVID-19 patients. We took advantage of the opportunity to classify them into immune... read more

Invasive Mechanical Ventilation Strategies For ICU Patients with COVID-19

Lung protective ventilation and prone positioning were used in many of the Danish ICU patients with COVID-19, but barotrauma, prolonged ventilation and death occurred frequently. A total of 774 patients were invasively... read more

Passport to Successful Outcomes for Patients Admitted to ICU: Meeting Patient Goals of Care

The second edition builds upon the previous content, exploring new and emerging evidence to enhance the structure and content of rehabilitation provided. It considers the additional impact of COVID-19 throughout each chapter.... read more

Passport to Successful Outcomes for Patients Admitted to ICU: Meeting Patient Goals of Care

7-day Fluid Balance Associated with Poor Outcomes

The net fluid balance in patients with sepsis 7 days following ICU administration was significantly related to mortality during hospitalization. Specifically, a 7-day fluid balance > 5,240 mL was associated with poor... read more

Establishment and Validation of a Risk Prediction Model for Sepsis-Associated Liver Injury in ICU Patients

This novel nomogram effectively predicts SALI risk in sepsis patients by integrating readily available clinical parameters. While external validation is needed, the model shows promise as a practical tool for early risk stratification,... read more

Lactic Acidosis with Metformin Accumulation in the ICU

Metformin-associated lactic acidosis (MALA) in ICUs often follow acute dehydration or infection, and these high-risk situations must be signals to prevent this serious ADR. Specific education programs for physicians and... read more

Increased Lactate Dehydrogenase to Albumin Ratio Associated with Short-term Mortality in Septic ICU Patients

Elevated lactate dehydrogenase to albumin ratio (LAR) was found to be significantly associated with an increased risk of all-cause mortality at 28 and 90 days in septic patients. LAR was suggested to be promising biomarker... read more

Procalcitonin Correlation with SEPSIS Severity in ICU Patients

High rates of morbidity and death are linked to sepsis, a potentially fatal illness. Procalcitonin (PCT), a biomarker of bacterial infection, is increasingly used in sepsis management to evaluate disease severity and guide... read more

Fast-Track in Cardiac Anesthesia: Cardiac Surgery in the Era of ERAS

This new book, focused on fast-track approaches in cardiac surgery, covers ERAS cardiac guidelines, explores the application of loco-regional anesthesia in cardiac surgery, and addresses all aspects related to early extubation... read more

Fast-Track in Cardiac Anesthesia: Cardiac Surgery in the Era of ERAS

Bedside Tunneled Dialysis Catheter Program Development and Implementation

The placement of ultrasound guided tunneled dialysis catheters at the bedside following a pre-procedural evaluation of the right jugular, brachiocephalic, and femoral veins is a safe option resulting in expedited patient... read more

Extubation Failure Risk Prediction Model Using Bedside Ultrasound

We have established a risk prediction model for extubation failure in mechanically ventilated ICU patients. This risk model base on bedside ultrasound parameters provides valuable insights for identifying high-risk patients... read more

ECMO vs. Cardiopulmonary Bypass in Lung Transplantation

Extracorporeal membrane oxygenation (ECMO) offers perioperative advantages in lung transplantation, reducing postoperative complications, one-year mortality, and recovery time compared to CPB. However, the longer total ischemic... read more

Successful Treatment of Unilateral Pulmonary Edema as Minimally Invasive Mitral Valve Surgery Complication

We successfully treated this patient using ECMO and independent lung ventilation. Several cases have been described in the literature, but the pathogenesis and risk factors of UPE remain unclear. Management depends on... read more

Plasma Proteome Temporal Changes Associated with Sepsis Mortality

Our proteomics approach revealed significant associations between changes in the plasma proteome within the first days of sepsis and mortality as well as disease severity. We identified and characterised the underlying... read more

Evaluation Effects of Nebulized Hypertonic Saline and Nebulized Corticosteroids in Patients with ARDS

Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute respiratory failure as a result of diffuse lung inflammation and oedema manifested by hypoxemia and stiffness in the lungs. This study... read more

Increased Sound Levels in the Cardiac ICU Associated with Increased Heart Rate, Blood Pressure, and Sedation

Sound levels in the CICU were consistently higher than recommended. An increase in heart rate, blood pressure and sedation utilization may suggest a stress response to persistent and sudden loud sounds. Given known negative... read more

Multidisciplinary Collaborative Bundled Care Improves Outcomes in ICU Patients with Endotracheal Intubation

Multidisciplinary analgesic and sedative bundled care has demonstrated the potential to decrease restraint use in patients undergoing endotracheal intubation and mechanical ventilation, reduce the need for analgesic and sedative... read more

Corticosteroid Therapy and Pulmonary Embolism in Polytrauma Patients

Pulmonary embolism is a frequent complication in polytrauma patients. The aim of our study was to evaluate the effect of low-dose corticosteroid therapy on the incidence of pulmonary embolism (PE) in polytrauma patients.... read more

Corticosteroid Therapy and Pulmonary Embolism in Polytrauma Patients

Long-term Prevalence of PTSD Symptom in Family Members of Severe COVID-19 Patients

The prevalence of PTSD-related symptoms among family members of severely ill COVID-19 patients stayed high up to 18 months after the patients' ICU discharge. Some showed delayed onset of PTSD-related symptoms in the remote... read more

Two Biomarkers Improve CRB-65 Predictability for Death Due to Community-Acquired Pneumonia

Augmenting CRB-65 (confusion, respiratory rate, blood pressure, and age 65 or older) score with troponin T high-sensitive (TnT-hs) and procalcitonin (PCT) help to predict death or intensive care unit (ICU) admission of patients... read more

In COVID-19 Patients Supported with ECMO, ICU Mortality Is Associated with the Blood Transfusion Rate

Three-quarters of patients 3 days in these centers between July 2020 and November 2021 were included in the analysis.... read more

Predicting ICU Admission in COVID-19-Infected Pregnant Women Using Machine Learning

Routinely collected clinical and laboratory data of COVID-19-infected pregnant women may help recognize high-risk groups who are more liable for complications and more severe course or prognosis and require an ICU admission.... read more