Tag: ICU
Mini Bronchoalveolar Lavage vs. Endo-Tracheal Aspirate in Diagnosing Bacterial Pneumonia in ICU
This study supports the use of endotracheal aspirate (ETA) as a cost-effective and efficient alternative to mBAL for the diagnosis of pneumonia in intubated ICU patients, particularly in settings where resources are limited.... read more
Temporary ICU – Preparedness Concept to Increase Capacity
The temporary ICU (TICU) concept demonstrates promising potential in enhancing preparedness and maintaining critical care surge capacity during pandemics or mass casualty incidents. While shortages of medical equipment,... read more
The predictive value of LAR for determining the need for ICU admission among hospitalized patients with community-acquired pneumonia
In this study, lactate-to-albumin ratio (LAR) was found to be a good predictor of ICU admissions in hospitalized patients with CAP and was non-inferior to PSI or CURB-65 scores. LAR was found to be a good predictor of... read more
Misunderstanding Buffering in Critical Illness
It is was disappointing to read the recent review in Intensive Care Medicine on buffering in metabolic acidosis. I consider this a "pre-Copernican" approach to acid–base that does not respect basic physical–chemical principles. The... read more
Prediction of Prolonged Mechanical Ventilation in the ICU via Machine Learning
Early recognition of risk factors for prolonged mechanical ventilation (PMV) could allow for early clinical interventions, prevention of secondary complications such as nosocomial infections, and effective triage of hospital... read more
Optimizing ICU Weaning: Globalizing Personalized Weaning Strategies
this study provides compelling evidence supporting the concept of individualized weaning in the ICU. By tailoring spontaneous breathing trial (SBT) methods to match specific patient conditions, it represents an essential... read more
Effect on Norepinephrine Administration Timing on Prognosis of Septic Shock Patients
Norepinephrine initiation ≤1 h is associated with lower 28-day mortality in patients with septic shock. Early norepinephrine administration is also associated with a shorter time to achieve MAP ≥65 mmHg, lower 24-h intravenous... read more
An Optimal Antibiotic Selection Framework for Sepsis Patients Using AI
In this work we present OptAB, the first completely data-driven online-updateable antibiotic selection model based on Artificial Intelligence (AI) for Sepsis patients accounting for side-effects. OptAB performs an iterative... read more
Personalized Therapies in ARDS
Acute respiratory distress syndrome (ARDS) can result from a variety of clinical conditions, causing lung injury either directly through local inflammation or indirectly because of systemic inflammatory mediators ARDS is... read more
Metabolic Disorders and Critically Ill Patients: From Pathophysiology to Treatment
Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes prevention or treatment of such disorders. This book is a comprehensive tool, allowing... read more
Mechanical Ventilation Timing in Sepsis
A recent study by Dr. Kim and colleagues examined the association between the timing of mechanical ventilation (MV) and clinical outcomes in ICU patients with sepsis. The study included 2440 adult sepsis patients from... read more
AI Interpretation of Chest Radiographs in the ICU. Ready for Prime Time?
Chest radiography (CXR) is the primary tool to visualize thoracic pathologies in the ICU. However, accurate interpretation of CXRs is challenging, even when imaging is performed under optimal conditions. This results... read more
The Infectious Disease Diagnosis: A Case Approach
This text uses cases to illustrate differential diagnoses of various infectious diseases. Unlike any other book on the market, this book is specifically designed for ease of use and can cater to a variety of medical professionals... read more
Outcomes of Older Adults With Sepsis at Admission to an ICU
Our study suggests that treating older adults with therapies recommended by the Surviving Sepsis Campaign may improve outcomes in this age group, although mortality remains high for older adults with sepsis. In addition,... read more
Rethinking Energy and Protein Provision for Critically Ill Patients
In critically ill patients, we suggest that energy and protein be delivered progressively in stable or recovering patients. If a patient deteriorates, regardless of days spent in the ICU, low-dose energy and protein should... read more
Early Tracheostomy in Ventilated COVID-19 Patients Reduces VAP Incidence
Tracheostomy can reduce mechanical ventilation (MV) duration, ICU and hospital length of stay (LOS), and ventilator-associated pneumonia (VAP) risk in critically ill patients. The timing of tracheostomy in COVID-19 patients... read more
Antibiotic prophylaxis reduced broad-spectrum antibiotics and length of stay in ICU patients with alcohol withdrawal induced refractory delirium tremens
Administration of TMP-SMX prophylaxis reduced the use of broad-spectrum antibiotics and ICU LOS in ICU-treated rDT patients. The retrospective study design should be considered when interpreting the results, and prospective... read more
Severe ICU-Acquired Hypernatremia: Prevalence, Risk Factors, Trajectory, Management, and Outcome
Severe hypernatremia occurred in the setting of inability to drink, near-absent measurement of urinary free water losses, diuretic therapy, fever, renal impairment, and near-absent or limited or delayed water administration.... read more
Awake, Walking, and Intubated – The ICU Breakthrough Giving Patients Their Lives Back
If they knew what it's like for patients surviving after the ICU, that sedation isn't sleep, and that they're being so traumatized and damaged by these normal practices, they would change this. Picture this: it's your... read more
Researchers to Study Online Therapy’s Potential to Prevent Cognitive Decline in ICU Survivors
Researchers from Indiana University Indianapolis, Regenstrief Institute and the IU School of Medicine’s Indiana Alzheimer’s Disease Research Center – led by Babar Khan, M.D., M.S., Sophia Wang, M.D., and Jesse Stewart,... read more
Pitfalls in the Management of Mechanical Ventilation: ARDS and Hypermetabolic States
Mechanical ventilation (MV) is a lifesaving intervention for patients with respiratory failure due to acute respiratory distress syndrome (ARDS) and septic shock. ARDS was first recognized in the late 1960s, approximately... read more
Non-Intensive Care Unit Feasibility for Ambulatory VV-ECMO Patients
Our data suggests that ambulatory veno-venous extracorporeal membrane oxygenation (VV-ECMO) patients may tolerate less than ICU level of care and may even progress to outpatient management as ECMO technology continues to... read more





