Tag: ICU
Automated Airway Care: The MICROINHALO Trial on Cuff Pressure and VAP Prevention
The MICROINHALO trial, an international cluster-randomized study across 10 ICUs, investigated whether automated airway management could reduce bacterial tracheal colonization in 250 critically ill intubated patients. The... read more
Blood, Sweat, and the ICU: Conquering Emergencies in Hematological Malignancies
Breakthroughs in cancer therapies and supportive care have dramatically improved life expectancy for patients with hematological malignancies (HM). However, living longer means more patients are surviving long enough to encounter... read more
Navigating the Complexities of ICU Intubation in Obesity
Managing the airway of critically ill patients with obesity in the ICU presents a high-stakes combination of anatomical and physiological hurdles. Increased adipose tissue narrows the upper airway and makes soft tissues highly... read more
Mastering Interprofessional Rehabilitation Across the ICU Continuum
Rehabilitation is a fundamental cornerstone of modern intensive care, crucial for minimizing long-term disability and maximizing a patient's functional recovery. Today's ICU patients are older, have multiple co-existing... read more
Wake-Up Call in Neurocritical Care: Propofol Outperforms Combined Sedation for Brain-Injured Patients
Sedation is vital for managing neurocritical care patients with acute brain injuries, yet finding the optimal strategy remains highly debated. This retrospective observational study analyzed 147 adult patients on invasive... read more
Handbook of Critical Care Medicine
The management of critically ill patients is an important and integral part of internal medicine practice. Often, junior doctors and medical students receive insufficient training in this area of medicine. There are important... read more
Parsing Pneumonia: Dual Definitions of Severe CABP Reveal Overlapping Risks and High Mortality
This study analyzed 67,439 patients diagnosed with severe community-acquired bacterial pneumonia (sCABP)—representing nearly a quarter of all CAPB admissions—to compare two major clinical definitions: ICU-sCABP (51.2%... read more
The Promise and Pitfalls of Bedside Muscle Ultrasound in the ICU
Evaluating muscle wasting and intensive care unit-acquired weakness (ICUAW) is critical, yet traditional methods fall short: computed tomography (CT) scans require risky patient transport, and standard physical exams require... read more
Out of Bed and Breathing Better: Armchair vs. Bed Positioning for Critically Ill Patients
Moving critically ill patients out of bed into an armchair is a common ICU practice, but its direct impact on oxygenation has lacked strong clinical evidence. This single-center randomized controlled trial evaluated 284 spontaneously... read more
Precision at Scale: Automating the SOFA Score for Smarter ICU Care
The Sequential Organ Failure Assessment (SOFA) score is a vital tool for diagnosing sepsis and predicting patient outcomes in the ICU, but its manual calculation is often plagued by human error and scalability issues. To... read more
COVID-19 in the Air: The Hidden Viral Footprint in Hospital Waiting Rooms
New research from the Kirby Institute reveals that COVID-19 genetic material is frequently present in hospital air during community outbreaks, even in facilities with high-quality ventilation. By sampling air and surfaces... read more
Breaking the Silos: How a Federated Europe Could Solve the Sepsis Puzzle
The landscape of critical care research is currently hindered by "data silos"—isolated pockets of patient information that are difficult to share due to privacy concerns and technical incompatibility. This narrative review... read more
Echocardiography for Intensivists
This book contains all the information that readers will require in order to perform echocardiography and to interpret the findings correctly. After an introductory chapter on the essential physics of ultrasonography,... read more
Power to the Patient: Rethinking Pain Control in the ICU
This scoping review of 12 relevant studies suggests that Patient-Controlled Analgesia (PCA) offers a promising path toward faster and more stable pain management for ICU patients. By allowing patients to self-administer small... read more
Balancing the Breath: Navigating the Brain-Lung Connection in Acute Brain Injury
This study explores the delicate tug-of-war between mechanical ventilation (MV) and outcomes for patients with Acute Brain Injury (ABI). The researchers highlight that the way we breathe for a patient can significantly influence... read more
The Great Escape: How ECMO Weaning Shifts Antibiotic Levels
This case study explores the complex pharmacological landscape of treating a 47-year-old patient with severe renal impairment and pneumonia using ceftazidime–avibactam (CAZ-AVI) while on VA-ECMO support. Researchers... read more
Life After the Pump: Quality of Life in Cardiac Surgery Survivors
Researchers have conducted a major study—the largest of its kind for this specific population—investigating the long-term quality of life (QoL) for patients who survived post-cardiotomy cardiogenic shock (PC-CS). By... read more
The Kidney Crisis: Acute Injury as a Predictor of ICU Survival
This extensive population-level study from Ontario, Canada, analyzed over 480,000 adult ICU admissions to clarify the relationship between Acute Kidney Injury (AKI) and patient outcomes. By utilizing outpatient baseline data... read more
Predicting Sepsis-associated Encephalopathy in Septic ICU Patients with AKI
Researchers developed a simple, interpretable nomogram to predict sepsis-associated encephalopathy (SAE) on day 1 in septic ICU patients who also have acute kidney injury (AKI), using data from the large MIMIC-IV database... read more
Metabolic Acidosis Worsens Cardiac Function and Vasopressor Needs in Septic Shock
In a prospective observational study conducted from January to December 2024 at Hospital de Especialidades No. 14, IMSS, in Veracruz, Mexico, researchers examined the cardiovascular effects of acute metabolic acidemia in... read more
Corrected Serum Calcium Levels Predict 28-Day Death Risk in Sepsis
In a large cohort study utilizing data from 7,627 sepsis patients in the eICU Collaborative Research Database, researchers uncovered a clear U-shaped relationship between corrected serum calcium (sCa) levels and 28-day mortality.... read more
Integration Equals Separation for CRRT Filter Lifespan in ECMO Patients (E-CRRT Trial)
The multicenter randomized controlled E-CRRT Trial, conducted from May 2021 to March 2025 at King Chulalongkorn Memorial Hospital (KCMH) and Central Chest Institute of Thailand (CCIT), compared two strategies for combining... read more
