Tag: ICU
Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine
In this review, we provide an overview of the role of fatty acid-derived lipid mediators as endogenous regulators of the inflammatory, anti-inflammatory and pro-resolving response and future directions for use of clinical... read more
Genetic Mechanisms of Critical Illness in COVID-19
Host-mediated lung inflammation is present, and drives mortality, in critical illness caused by COVID-19. Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development. Here... read more
Improved Oxygenation After Prone Positioning May Be a Predictor of Survival in Patients With ARDS
We found a significant difference in the Pao2:Fio2 ratio after the first prone positioning between ICU survivors and nonsurvivors. The improvement in oxygenation after the first prone positioning was a significant predictor... read more
Nurses’ knowledge and practices of physical restraints in ICU
The mean scores of nurses' knowledge and practices were 61.5 (SD = 12.1) and 57.4 (SD = 9.7), respectively. More than half of nurses had poor knowledge of PR use and incorrect practice of implementing PR (51.5% and 60.5%,... read more
Clinical characteristics of critically ill patients with COVID-19
In this study of critical patients infected by SARS-CoV-2 in a high-complexity hospital, the majority were comorbid elderly men, a large percentage required invasive mechanical ventilation, and ICU mortality was 25%. Design... read more
ECG Pointers: Cocaine and ST Elevation
This ECG comes from a 21-year-old male with a history of cocaine abuse. When I say ‘history’, I mean that he just snorted some cocaine and now he has chest pain. He looks uncomfortable and sweaty, and keeps... read more
Risk factors and events in the adult ICU associated with pain as self-reported at the end of the intensive care unit stay
The short-term and long-term consequences of the most frequent painful procedures performed in the ICU are unclear. This study aimed to identify the risk factors associated with pain-related discomfort perceived by critically... read more
Will the asthma revolution fostered by biologics also benefit adult ICU patients?
Asthma exacerbations are inflammatory events that rarely result in full hospitalization following an ER visit. Unfortunately, certain patients require prolonged support, including occasional external lung support through... read more
Caring for the Sickest COVID-19 Patients: An ICU Story
In an article for the latest issue of Stanford Medicine magazine, I provide a glimpse into the journey Free and his front-line Stanford Health Care colleagues took -- from Day 1 through the following weeks and months -- to... read more
Fishman’s Pulmonary Diseases and Disorders
Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with... read more
Surgery guidance updated for hospitals struggling with capacity constraints
Four healthcare groups again updated their guidance for hospitals to maintain essential surgeries during the COVID-19 pandemic. The American Hospital Association, American College of Surgeons, American Society of Anesthesiologists... read more
Epidemiology of Invasive Pulmonary Aspergillosis Among COVID-19 Intubated Patients
We found a high incidence of CAPA among critically ill COVID-19 patients and that its occurrence seems to change the natural history of disease. A total of 108 patients were enrolled. Prospective, multicentre study... read more
Increased Dead Space Ventilation and Refractory Hypercapnia in Patients with COVID-19
We speculate that thromboinflammation with pulmonary microvasculature occlusion leads to a sudden increase in dead space and shunt resulting in severe hypercapnia and hypoxemia in coronavirus disease 2019 patients. Early... read more
The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort
This study indicates that portal and hepatic flows may be clinical useful tools to help identify patients at risk for renal injury. It is likely that they are indicative of elevated right atrial pressure causing venous congestion,... read more
Critical Care Beds Are No Use Without Enough Specialist Staff
In 2020 there have been announcements of the expansion of critical care capacity across the NHS, while at the same time headlines have detailed stories of hospitals running out of critical care beds. And this week dire warnings... read more
Practical Guidance for Evidence-Based ICU Family Conferences
Because most critically ill patients lack decision-making capacity, physicians often ask family members to act as surrogates for the patient in discussions about the goals of care. Therefore, clinician-family communication... read more
Balancing Intervention and Inaction During the COVID-19 Pandemic
More than 38 million people worldwide have been infected with the severe acute respiratory syndrome (SARS) coronavirus 2, creating intense pressure on clinicians to offer state-of-the-art, life-saving treatment to patients. The... read more
Factors Associated to ICU Mortality in Critically Ill Patients Infected with COVID-19 in Spain
Older COVID-19 patients with higher APACHE II scores on admission, those who developed AKI grades II or III and/or septic shock during ICU stay had an increased risk-of-death. ICU mortality was 31%. A total of 663 patients... read more
Critical Care Medicine: Principles of Diagnosis and Management in the Adult
Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually... read more
Clinical Communication with Families in the Age of COVID-19
The admission of a critically ill patient to an intensive care unit (ICU) is a distressing event for the patient, their family and friends, which has been amplified by the impact of the covid-19 pandemic. Many hospitals... read more
Effect of Early Activity Combined with Early Nutrition on Acquired Weakness in ICU Patients
This trial has the potential to identify a novel strategy for preventing or managing ICU-AW. The findings may increase the clinical knowledge about nutrition and mobilization interventions for people with ICU-AW, and contribute... read more
Stress Hyperglycemia and Mortality in Subjects With Diabetes and Sepsis
Stress-induced hyperglycemia is a relevant prognostic factor also in the presence of diabetes. Mild-to-moderate stress hyperglycemia is considered a protective reaction to providing fuel for the immune system and brain at... read more
