Most pediatric ICU physicians don’t use current guidelines to diagnose acute kidney injury

A study by University at Buffalo researchers has shown that physicians in pediatric intensive care units are not using the newest guidelines to diagnose acute kidney injury (AKI) in critically ill children, a practice that... read more

Septic shock with no diagnosis at 24 hours: a pragmatic multicenter prospective cohort study

The lack of a patent source of infection after 24 hours of management of shock considered septic is a common and disturbing scenario. A multicenter observational cohort study in ten intensive care units (ICU) in France.... read more

Performance of a Modern Glucose Meter in ICU

Performance of a Modern Glucose Meter in ICU and General Hospital Inpatients: 3 Years of Real-World Paired Meter and Central Laboratory Results. Due to accuracy concerns, the Food and Drug Administration issued guidance to... read more

Restricting volumes of resuscitation fluid in adults with septic shock after initial management

A protocol restricting resuscitation fluid successfully reduced volumes of resuscitation fluid compared with a standard care protocol in adult ICU patients with septic shock.... read more

The Association of Early Combined Lactate and Glucose Levels with Subsequent Renal and Liver Dysfunction

Abnormal combined lactate and glucose measurements may provide an early indication of organ dysfunction. In critically ill patients a 'normal' glucose with an elevated lactate should not be considered desirable, as this combination... read more

Standardize ICU Admission Practices to Cut Costs

Hospitals that admitted patients to ICUs more often were more likely to routinely perform invasive procedures and incur higher costs with no commensurate improvement in mortality.... read more

Hospitals with most heart patients in ICU have worse results: Study

Heart attack or heart failure patients are more likely to get worse or die at hospitals that are more likely to treat them in the ICU, a new study suggests.... read more

Glycemic control, mortality, and hypoglycemia in critically ill patients

Network meta-analysis showed no mortality benefit of tight glycemic control in critically ill patients, but fivefold more hypoglycemia versus mild or very mild control. Thirty-six randomized trials (17,996 patients) were... read more

Preventing Harm in the ICU – Building a Culture of Safety and Engaging Patients and Families

Preventing harm remains a persistent challenge in the ICU despite evidence-based practices known to reduce the prevalence of adverse events. This review seeks to describe the critical role of safety culture and patient and... read more

Clinicians’ Perception and Experience of Organ Donation From Brain-Dead Patients

ICU clinicians are primarily involved in organ donation after brain death of ICU patients. Their perceptions of organ donation may affect outcomes. Our objective was to describe ICU clinician’s perceptions and experience... read more

Early Troponin I in Critical Illness and its Association with Hospital Mortality

TnI is an independent predictor of hospital mortality and correlates most highly with the APS component of APACHE II. It does not improve risk prediction. We would not advocate the adoption of routine troponin analysis on... read more

An Alternative Consent Process for Minimal Risk Research in the ICU

Seeking consent for minimal risk research in the ICU poses challenges, especially when the research is time-sensitive. Our aim was to determine the extent to which ICU patients or surrogates support a deferred consent process... read more

Association Between Survival and Time of Day for RRT Calls

Rapid response team activation is less frequent during the early morning and is followed by a spike in mortality in the 7 AM hour. These findings suggest that failure to rescue deteriorating patients is more common overnight.... read more

Mastering Intensive Care

Is the patient the centre of every action you take in the ICU? Do you exude calm and enthusiastic energy and greet other team members warmly and genuinely? Do you seek pleasure in seeing colleagues grow to become more skilled... read more

Controlled Trial to Improve Resident Sign-out in a Medical ICU

Poor sign-out or handover of care may lead to preventable patient harm. Critically ill patients in intensive care units (ICU) are complex and prone to rapid clinical deterioration. If clinical deterioration occurs, timeliness... read more

Candida Auris a “Perfect Storm” Superbug

How an invasive fungus got health officials' attention. Try as they might, the infection control specialists at Royal Brompton Hospital could not eradicate the invasive fungus that was attacking already gravely ill patients... read more

Increased ICU Costs for Opioid Overdoses

ICU costs for treating opioid overdose patients increased 58% in a seven-year span, and annual deaths almost doubled, according to a study that included 162 academic hospitals. ICU admissions increased 34% over the study... read more

Extended ICU Visitation Model Reduces Delirium

In this medical-surgical ICU, an extended visitation model was associated with reduced occurrence of delirium and shorter length of delirium/coma and ICU stay. Two hundred eighty-six patients were enrolled (141 restricted... read more

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

EBUS-TBNA is a safe procedure. The highest complication rate reported is 1.44%. Additionally, the scope damage could be encountered in 1.33% of cases and occasionally the TBNA needle could malfunction. The complications are... read more

nutritionDay ICU

An worldwide prevalence study to determine the nutrition practice in the ICUs and the associated outcome across the world, a yearly 1 day cross sectional audit was performed from 2007 to 2013. This very large collaborative... read more

Worldwide Survey of the ABCDEF Bundle in the ICU

The current implementation of the ABCDEF bundle varies across individual components and regions. We identified specific targets for quality improvement and adoption of the ABCDEF bundle. Our data reflect a significant but... read more

Safety Hazards During Intrahospital Transport

A prospective observational study. Data from participant observations of the intrahospital transport process were collected over a period of 3 months. Findings suggest that intrahospital transport is a hazardous process for... read more