Tag: infection
Rapid and Accurate Sepsis Identification Using AI
This study demonstrates that by providing streamlined predictions using CBC+DIFF data without requiring extensive clinical parameters, the AI-CDSS can be seamlessly integrated into clinical workflows, enhancing rapid, accurate... read more
Managing Recurrent Septic Shock – Dual Blood Purification with CytoSorb and oXiris
This case report presents a patient with recurrent septic shock who experienced significant clinical improvement after receiving adjunctive treatment with a combination of continuous renal replacement therapy (CRRT) using... read more
Predicting Sepsis Outcomes – Efficacy of Early Warning Scores
In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments... read more
Prognostic Value of Composite Inflammatory Markers in COPD Patients
Elevated systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), pan-immune inflammation value (PIV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are associated... read more
Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection
Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more
Zosyn vs. Efepime: Which One Is Safer?
While both piperacillin-tazobactam and cefepime are commonly used to treat infections caused by Pseudomonas aeruginosa in hospitalized patients, there is a concern that piperacillin-tazobactam may lead to acute kidney injury... read more
Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection
The interplay of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and Clostridioides difficile infection (CDI) poses a critical clinical challenge. The resultant inflammatory milieu and its impact... read more
Multidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory Status Epilepticus and Nontuberculous Mycobacterial CNS Infections in the ICU
The diagnosis and management of complex neurological conditions such as New-Onset Refractory Status Epilepticus (NORSE) and central nervous system (CNS) infections caused by non-tuberculous mycobacteria (NTM) pose substantial... read more
RSV Infection – Epidemiology and Clinical Risk Factors
Respiratory syncytial virus (RSV) infection is the most frequent reason for hospitalization of infants in developed countries. Premature birth without or, especially, with chronic lung disease of prematurity, congenital heart... read more
Temporal Trends of RSV-Associated US ICU Admissions
Wide variations in regional and seasonal patterns in hospital and ICU admissions were noted in children with respiratory syncytial virus–associated acute respiratory illness across the United States. Results from our... read more
RSV Outbreak in a Pediatric ICU
The Royal Liverpool Children's Hospital—Alder Hey pediatric intensive care unit (PICU) usually has a low rate of nosocomial respiratory syncytial virus (RSV) infection. We report and analyze a major outbreak of nosocomial... read more
Respiratory Syncytial Virus: Diagnosis and Treatment
Respiratory syncytial virus (RSV) is a respiratory virus which results in symptoms similar to cold. This virus spreads through the drops coming from the nose and throat of an infected person, while sneezing and coughing.... read more
Immunocompromised People May Not Produce Enough Protective Antibodies Against RSV After Vaccination
This study demonstrated heterogeneous antibody response to respiratory syncytial virus (RSV) vaccines among immunocompromised persons. In contrast to universal seroconversion and preF IgG fold rises greater than 10 in immunocompetent... read more
Clinical Outcomes of Early Phenotype-Desirable Antimicrobial Therapy for Enterobacterales Bacteremia
This is first study to compare clinical outcomes between patients with E coli, K pneumoniae, K oxytoca, and P mirabilis BSIs receiving early PDAT vs delayed PDAT using DOOR analysis. Receiving early phenotype-desirable... read more
Single-use vs. Multiple-use Endotracheal Suction Catheters Flushed with Chlorhexidine in Mechanically Ventilated ICU Patients
The aim of this feasibility randomized controlled trial (fRCT) is to assess the practicality and impact of using single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine on the incidence of... read more
Ventilator-associated Lung Disease: A Complex Reality in the ICU
Mechanical ventilation, by tracheal intubation or tracheostomy, is the common supplementary treatment for several reasons for hospitalization. Since the advent of long-term mechanical ventilation during the polio epidemic. In... read more
Emergence of Ventilator Associated Pneumonia in Critical Care Units
In intensive care unit, the care of critically ill patients is a primary component of modern medicine. Intensive care units create potential for recovery in patients who otherwise may not have survived. They are, however,... read more
Heparin-binding Protein Predicts Bacterial Infection in Severe Polytrauma Patients
In patients with severe polytrauma, heparin-binding protein may predict bacterial infection. Combining heparin-binding protein, PCT, and neutrophils may improve bacterial infection prediction. HBP provides a referenceable... read more
Lactic Acidosis with Metformin Accumulation in the ICU
Metformin-associated lactic acidosis (MALA) in ICUs often follow acute dehydration or infection, and these high-risk situations must be signals to prevent this serious ADR. Specific education programs for physicians and... read more
