Tag: infection
Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury
During the last decade, experimental and clinical studies have demonstrated that isolated acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential target organs... read more
Short-term and Long-term Rates of Postacute Sequelae of COVID-19 Infection
In this systematic review, we evaluated the temporal progression of clinical abnormalities experienced by patients who recovered from an infection with SARS-CoV-2, starting with a mean of 30 days post–acute illness and... read more
Scripts for Subconjunctival Hemorrhage, Fainting and Syncope, and Viral Illness
Many parts of the ED encounter interfere with patient or family comprehension, not the least of which is the ED's noisy, hurried environment. But other factors affect what they understand and remember about the encounter—their... read more
We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt
Melbourne’s second wave of COVID-19 last year, which led to a lockdown lasting more than 100 days, provided us with many lessons about controlling transmission. Some of these are pertinent as New South Wales endures its... read more
Convalescent Plasma for COVID-19 in Hospitalised Patients
Convalescent plasma (CP) and standard of care (SOC) did not result in a higher proportion of clinical improvement on at day 28 in hospitalised patients with COVID-19 compared to SOC alone. This is an investigator-initiated,... read more
COVID-19 Immune Evasion by the B.1.427/B.1.429 Variant of Concern
As battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of concern because they... read more
COVID-19 Variant Classifications and Definitions
Genetic variants of SARS-CoV-2 have been emerging and circulating around the world throughout the COVID-19 pandemic. Viral mutations and variants in the United States are routinely monitored through sequence-based surveillance,... read more
Fungal Infections Complicating COVID-19
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread globally to pandemic proportions. Although the majority of cases have asymptomatic or mild infections,... read more
Time Course of Risk Factors Associated with COVID-19 Mortality
The present multicentric study describes 1,260 critically ill patients with COVID-19-associated acute respiratory failure consecutively admitted to 24 Italian ICUs during the first pandemic wave. This study specifically... read more
COVID-19 Variants in Patients with Immunosuppression
Patients with immunosuppression are at risk for prolonged infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In several case reports, investigators have indicated that multimutational SARS-CoV-2... read more
Full Vaccination Suppresses COVID-19 Delta Variant Mutation Frequency
This study presents the first evidence that full vaccination against COVID-19 suppresses emergent mutations of SARS-CoV-2 delta variants. An evolution algorithm, Tajima's D test with a threshold value as -2.50, can provide... read more
NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection
A panel of experts convened by the National Institutes of Health has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19. The panel also offers guidance... read more
The Harriet Lane Handbook: Mobile Medicine Series
Written "by residents, for residents" and reviewed by expert faculty at The Johns Hopkins Hospital, Lauren Kahl, MD and Helen K. Hughes, MD, MPH, The Harriet Lane Handbook, 21st Edition, remains your #1 source of pediatric... read more
COVID-19, Online Shaming, and Health-care Professionals
Stigma and shame have been features of past pandemics. The stigma associated with disease can be experienced as shame by those who spread it. In almost all human cultures, there is shame attached to being “contaminated”,... read more
Junior Doctors Write to Young People to Acknowledge Vaccine Concerns
A group of junior doctors from Scotland have written to young people in their age group to try to ease concerns they may have about receiving the covid-19 vaccine. In an open letter sent on Friday 6 August the doctors,... read more
Cystic Fibrosis in the COVID-19 Pandemic
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the development of life-threatening COVID-19 are believed to disproportionately affect certain at-risk populations. However, it is not clear whether... read more
Progressive Increase in Virulence of COVID-19 Variants
The progressive increase in transmissibility and virulence of SARS-CoV-2 VOCs will result in a significantly larger, and more deadly, pandemic than would have occurred in the absence of variants of concern (VOC) emergence. The... read more
Carotid Blowout Syndrome: Modern Trends in Management
Carotid blowout syndrome (CBS) refers to rupture of the carotid artery and is an uncommon complication of head and neck cancer that can be rapidly fatal without prompt diagnosis and intervention. CBS develops when a damaged... read more
Intubation Timing As Determinant Of Outcome in Patients with ARDS By COVID-19 Infection
In COVID-19 patients, late intubation, Pafi ... read more
COVID-19 Restructures the Host Chromatin Architecture
SARS-CoV-2 has made >190-million infections worldwide, thus it is pivotal to understand the viral impacts on host cells. Many viruses can significantly alter host chromatin, but such roles of SARS-CoV-2 are largely unknown.... read more
Neuropsychiatric Disorders and COVID-19
We read with interest the Article by Maxime Taquet and colleagues1 in The Lancet Psychiatry that evaluated a large population (n=236 379) for neurological and psychiatric complications of COVID-19 via analysis of diagnostic... read more
Moderna Vaccine 94.1% Efficacy Preventing Symptomatic COVID-19
The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants... read more
