Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More... read more

Biggest AMR dilemma: to give, or not to give antibiotics?

Biggest AMR dilemma: to give, or not to give antibiotics?

Sepsis (a dysregulated reaction of the body to infection with 50 million cases per year) must be treated with antibiotics as soon as it is suspected — ideally, within the first hour. Antibiotics are thus easily administered... read more

Marburg Virus Disease Outbreaks in Equatorial Guinea and Tanzania

Marburg Virus Disease Outbreaks in Equatorial Guinea and Tanzania

The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to inform clinicians and public health departments in the United States about two confirmed outbreaks of Marburg... read more

Antifungal Stewardship in Critically Ill Patients

Antifungal Stewardship in Critically Ill Patients

Antifungal stewardship (AFS) can improve performance measures and decrease antifungal consumption, with no negative impact on outcomes. β-D-glucan (BDG) are helpful to stop unnecessary treatment in patients with IC,... read more

Regular Old Pneumonia Treatment Just Got Better

Regular Old Pneumonia Treatment Just Got Better

In 2020, COVID-19 pneumonia became so common that "old-fashioned" bacterial pneumonia suddenly seemed rare. They look very different on x-ray. See if you can spot the differences. A new study from France tipped the scales... read more

Optimal Bundle of Recommendations for Sepsis

Optimal Bundle of Recommendations for Sepsis

The aim of this retrospective cohort study was to identify among the Surviving Sepsis Campaign (SSC) guidelines the optimal bundle of recommendations that minimize 28-day mortality. The bundle of six recommendations is... read more

Management of Dysregulated Immune Response in the Critically Ill

Management of Dysregulated Immune Response in the Critically Ill

This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic... read more

PLASMIC Score Role in the Management of Thrombotic Thrombocytopenic Purpura

PLASMIC Score Role in the Management of Thrombotic Thrombocytopenic Purpura

At centers that are resource-limited and where ADAMTS-13 testing is not readily available, it is imminent that treatment is started immediately based on the clinical presentation and PLASMIC score. A PLASMIC score can... read more

Advances in Microbiology, Infectious Diseases and Public Health: Volume 15

Advances in Microbiology, Infectious Diseases and Public Health: Volume 15

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues... read more

Emergence of Ventilator Associated Pneumonia in Critical Care Units

Emergence of Ventilator Associated Pneumonia in Critical Care Units

In intensive care unit, the care of critically ill patients is a primary component of modern medicine. Intensive care units create potential for recovery in patients who otherwise may not have survived. They are, however,... read more

Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy

Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy

Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular.... read more

COVID-19 Treatment Guidelines New Version Published

COVID-19 Treatment Guidelines New Version Published

The COVID-19 Treatment Guidelines Panel (the Panel) is pleased to announce the publication of an updated version of the Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. In the United States, the prevalence of... read more

Early Identification of Intra-abdominal Infection and Sepsis

Early Identification of Intra-abdominal Infection and Sepsis

This case report illustrates the ability of the novel biomarker pancreatic stone protein (PSP) concentrations to act as a warning sign, allowing the early identification of intra-abdominal infection and post-operative peritonitis... read more

Extracorporeal Life Support: The ELSO Red Book, 6th Edition

Extracorporeal Life Support: The ELSO Red Book, 6th Edition

Written by over two hundred experts from around the world, this new edition is the definitive reference text on Extracorporeal Life Support, providing both the latest evidence and practical advice on how to clinically manage... read more