Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients

Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients

Compared with surgical cannulation, percutaneous cannulation was independently associated with lower in-hospital mortality and fewer complications. Among 12,592 patients meeting study inclusion, 9,249 (73%) underwent percutaneous... read more

Defining COVID-19 Associated Pulmonary Aspergillosis

Defining COVID-19 Associated Pulmonary Aspergillosis

The reported prevalence of CAPA in ICU patients with COVID-19 varies greatly by study and may be related to surveillance protocols and inconsistent definitions which may inflate the prevalence of this complication. Further... read more

Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis

Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis

Bacterial sepsis patients had early, severe inflammation, profound immune suppression, and life-threatening organ dysfunction that resolved over time; SARS-CoV-2 patients had less severe early inflammation and organ dysfunction... read more

Long-term Cardiovascular Outcomes of COVID-19

Long-term Cardiovascular Outcomes of COVID-19

The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used... read more

Critical COVID-19 Pneumonia Determinants

Critical COVID-19 Pneumonia Determinants

SARS-CoV-2 infection is benign in most individuals but, in approx. 10% of cases, it triggers hypoxemic COVID-19 pneumonia, which becomes critical in ˜3% of cases. The ensuing risk of death (˜1%) doubles every five years... read more

High-Dose Dexamethasone vs. Tocilizumab in COVID-19 Pneumonia

High-Dose Dexamethasone vs. Tocilizumab in COVID-19 Pneumonia

Our study findings discourage the use of high doses of dexamethasone in the management of moderate to severe COVID-19 ARDS. The routine use of such high doses to mitigate the inflammatory cytokine storm in these patients... read more

Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine

Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine

Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine 4E has been fully updated and revised. The clinical diagnostic approach to common infectious disease problems in the CCU is the underlying theme... read more

Long-Term Opioid Prescription Linked to Higher Risk of Hepatitis C

Long-Term Opioid Prescription Linked to Higher Risk of Hepatitis C

Exposure to long-term prescription opioid therapy was linked to a three times higher risk of HCV seroconversion compared to individuals who were prescription opioid-naïve or acute. Prescription opioid use is associated... read more

Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19

Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19

The results of this randomized clinical trial demonstrated that ciclesonide did not achieve the primary efficacy end point of reduced time to alleviation of all COVID-19–related symptoms. A total of 413 participants... read more

1-year Mortality After COVID-19 ICU Admission

1-year Mortality After COVID-19 ICU Admission

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe disease in some patients. Patients can experience severe disabilities after intensive care unit (ICU) admission due to coronavirus disease... read more

Post-acute Neurological Consequences of COVID-19

Post-acute Neurological Consequences of COVID-19

COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity. Our world has witnessed over 275 million confirmed cases of COVID-19... read more

Epidemiology, Outcomes, and Trends of Patients with Sepsis and Opioid-Related Hospitalizations

Epidemiology, Outcomes, and Trends of Patients with Sepsis and Opioid-Related Hospitalizations

Sepsis is an important cause of morbidity and mortality in patients with opioid-related hospitalizations, and opioid-related hospitalizations contribute disproportionately to sepsis-associated deaths among younger patients.... read more

Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection

Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection

A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here, we studied individuals with LC compared to... read more

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

The research will be retrospective, and will include a review of medical history of all patients admitted in the COVID-19 ICU of the University hospital Osijek during 2020 and 2021. Associated comorbidity, hospital admission... read more